Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
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Title
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
Authors
Keywords
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Journal
OncoImmunology
Volume -, Issue -, Pages 1-32
Publisher
Informa UK Limited
Online
2018-08-27
DOI
10.1080/2162402x.2018.1503032
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- The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11
- (2016) Constantia Pantelidou et al. Oncotarget
- Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas
- (2016) Shuhei Osaki et al. Scientific Reports
- Mesenchymal stem cells enhance the oncolytic effect of Newcastle disease virus in glioma cells and glioma stem cells via the secretion of TRAIL
- (2016) Gila Kazimirsky et al. Stem Cell Research & Therapy
- Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies
- (2016) Juan J. Rojas et al. Cell Reports
- Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
- (2016) Tianli Xia et al. Cell Reports
- The oncolytic virus ΔPK has multimodal anti-tumor activity
- (2016) Laure Aurelian et al. Pathogens and Disease
- Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma
- (2016) David F. Bauer et al. Journal of Immunology Research
- Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma
- (2016) Mahua Dey et al. Stem Cell Reports
- Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma
- (2016) Daxa M. Patel et al. Human Gene Therapy Clinical Development
- Safety Studies in Tumor and Non-Tumor-Bearing Mice in Support of Clinical Trials Using Oncolytic VSV-IFNβ-NIS
- (2016) Lianwen Zhang et al. Human Gene Therapy Clinical Development
- Fine-tuning the CAR spacer improves T-cell potency
- (2016) Norihiro Watanabe et al. OncoImmunology
- CAR-T cell therapy in gastrointestinal tumors and hepatic carcinoma: From bench to bedside
- (2016) Qi Zhang et al. OncoImmunology
- The association of clinical outcome and peripheral T-cell subsets in metastatic colorectal cancer patients receiving first-line FOLFIRI plus bevacizumab therapy
- (2016) Mario Roselli et al. OncoImmunology
- Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop
- (2016) Roch Houot et al. OncoImmunology
- Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells
- (2016) Carole Achard et al. OncoImmunology
- Antitumor vaccination of prostate cancer patients elicits PD-1/PD-L1 regulated antigen-specific immune responses
- (2016) Brian T. Rekoske et al. OncoImmunology
- Human CD1c+ DCs are critical cellular mediators of immune responses induced by immunogenic cell death
- (2016) Stefania Di Blasio et al. OncoImmunology
- Adaptive T cell responses induced by oncolytic Herpes Simplex Virus-granulocyte macrophage-colony-stimulating factor therapy expanded by dendritic cell and cytokine-induced killer cell adoptive therapy
- (2016) Jun Ren et al. OncoImmunology
- Results of a phase I–II study of adjuvant concurrent carboplatin and accelerated radiotherapy for triple negative breast cancer
- (2016) Silvia C. Formenti et al. OncoImmunology
- Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma
- (2016) Ioannis Karydis et al. OncoImmunology
- Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition
- (2016) Patricia Kleinpeter et al. OncoImmunology
- Syngeneic Syrian hamster tumors feature tumor-infiltrating lymphocytes allowing adoptive cell therapy enhanced by oncolytic adenovirus in a replication permissive setting
- (2016) Mikko Siurala et al. OncoImmunology
- PD-1/PD-L1 inhibitors in multiple myeloma: The present and the future
- (2016) T. Jelinek et al. OncoImmunology
- Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies
- (2016) Laura Evgin et al. Molecular Therapy-Oncolytics
- Evaluation of polymer shielding for adenovirus serotype 6 (Ad6) for systemic virotherapy against human prostate cancers
- (2016) Tien V Nguyen et al. Molecular Therapy-Oncolytics
- Recombinant mumps virus as a cancer therapeutic agent
- (2016) Arun Ammayappan et al. Molecular Therapy-Oncolytics
- Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy
- (2016) Marcin P Komorowski et al. Molecular Therapy-Oncolytics
- Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity
- (2016) Mari Hirvinen et al. Molecular Therapy-Oncolytics
- A novel, polymer-coated oncolytic measles virus overcomes immune suppression and induces robust antitumor activity
- (2016) Kaname Nosaki et al. Molecular Therapy-Oncolytics
- Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy
- (2016) Catherine Dold et al. Molecular Therapy-Oncolytics
- Oncolytic vesicular stomatitis virus expressing interferon-σ has enhanced therapeutic activity
- (2016) Marie-Claude Bourgeois-Daigneault et al. Molecular Therapy-Oncolytics
- Phase I study with ONCOS-102 for the treatment of solid tumors – an evaluation of clinical response and exploratory analyses of immune markers
- (2016) Tuuli Ranki et al. Journal for ImmunoTherapy of Cancer
- Into the clinic: Talimogene laherparepvec (T-VEC), a first-in-class intratumoral oncolytic viral therapy
- (2016) Hasan Rehman et al. Journal for ImmunoTherapy of Cancer
- Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study
- (2016) Howard L. Kaufman et al. Journal for ImmunoTherapy of Cancer
- Human Trial of a Genetically Modified Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of Pancreatic Cancer
- (2016) Kaitlyn J. Kelly et al. EBioMedicine
- Oncolytic Viruses: Therapeutics With an Identity Crisis
- (2016) Caroline J. Breitbach et al. EBioMedicine
- Hormesis, cell death and aging
- (2016) Isabelle Martins et al. Aging-US
- Experimental Adaptation of Rotaviruses to Tumor Cell Lines
- (2016) Carlos A. Guerrero et al. PLoS One
- Combined expression of miR-34a and Smac mediated by oncolytic vaccinia virus synergistically promote anti-tumor effects in Multiple Myeloma
- (2016) Wen Lei et al. Scientific Reports
- Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia
- (2015) W. Shen et al. BLOOD
- Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors
- (2015) Miguel A. Villalona-Calero et al. CANCER
- VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection
- (2015) Rozanne Arulanandam et al. CANCER CELL
- Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents
- (2015) Lorenzo Galluzzi et al. CANCER CELL
- TGF Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response
- (2015) J. Han et al. CANCER RESEARCH
- Systemic Immune Activity Predicts Overall Survival in Treatment-Nai ve Patients with Metastatic Pancreatic Cancer
- (2015) M. R. Farren et al. CLINICAL CANCER RESEARCH
- Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy
- (2015) J. J. Rojas et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Mechanism of Action for Talimogene Laherparepvec, a New Oncolytic Virus Immunotherapy
- (2015) F. J. Kohlhapp et al. CLINICAL CANCER RESEARCH
- The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma
- (2015) N. Martinez-Velez et al. CLINICAL CANCER RESEARCH
- Prostate Cancer Immunotherapy with Sipuleucel-T: Current Standards and Future Directions
- (2015) Xiao X Wei et al. Expert Review of Vaccines
- Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases
- (2015) Yuefeng Yang et al. HUMAN GENE THERAPY
- Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
- (2015) Robert H.I. Andtbacka et al. JOURNAL OF CLINICAL ONCOLOGY
- Retargeting Oncolytic Vesicular Stomatitis Virus to Human T-Cell Lymphotropic Virus Type 1-Associated Adult T-Cell Leukemia
- (2015) Dillon Betancourt et al. JOURNAL OF VIROLOGY
- Targeted Photodynamic Virotherapy Armed with a Genetically Encoded Photosensitizer
- (2015) K. Takehara et al. MOLECULAR CANCER THERAPEUTICS
- Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses
- (2015) Norman Woller et al. MOLECULAR THERAPY
- Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity
- (2015) Carolina S Ilkow et al. NATURE MEDICINE
- Oncolytic viruses: a new class of immunotherapy drugs
- (2015) Howard L. Kaufman et al. NATURE REVIEWS DRUG DISCOVERY
- Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling
- (2015) Julia V. Cockle et al. NEURO-ONCOLOGY
- Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release
- (2015) K A Garant et al. ONCOGENE
- Genome-wide lentiviral shRNA screen identifies serine/arginine-rich splicing factor 2 as a determinant of oncolytic virus activity in breast cancer cells
- (2015) S T Workenhe et al. ONCOGENE
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
- (2015) M. Vetizou et al. SCIENCE
- Tumour necrosis factor-alpha-induced protein 8 (TNFAIP8) expression associated with cell survival and death in cancer cell lines infected with canine distemper virus
- (2015) J. A. Garcia et al. Veterinary and Comparative Oncology
- Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer
- (2015) Manish R. Patel et al. Oncotarget
- Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity
- (2015) Bing-Hua Su et al. Oncotarget
- Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases
- (2015) Valerio Leoni et al. Oncotarget
- The oncolytic virus dl922-947 reduces IL-8/CXCL8 and MCP-1/CCL2 expression and impairs angiogenesis and macrophage infiltration in anaplastic thyroid carcinoma
- (2015) Carmela Passaro et al. Oncotarget
- Oncolytic viruses: perspectives on clinical development
- (2015) James Burke et al. Current Opinion in Virology
- MicroRNAs and oncolytic viruses
- (2015) Autumn J Ruiz et al. Current Opinion in Virology
- The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors
- (2015) Valentina Gatta et al. PLoS Pathogens
- Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment
- (2015) Laetitia Fend et al. OncoImmunology
- Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
- (2015) Kirsten Ridder et al. OncoImmunology
- Oncolytic virotherapy for treatment of breast cancer, including triple-negative breast cancer
- (2015) Simona Bramante et al. OncoImmunology
- Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion
- (2015) Bharat K. R. Chaganty et al. OncoImmunology
- Doubling the blockade for melanoma immunotherapy
- (2015) Lorenzo Galluzzi et al. OncoImmunology
- CXCL11-Armed oncolytic poxvirus elicits potent antitumor immunity and shows enhanced therapeutic efficacy
- (2015) Zuqiang Liu et al. OncoImmunology
- First oncolytic virus approved for melanoma immunotherapy
- (2015) Jonathan Pol et al. OncoImmunology
- Perspectives on sipuleucel-T: Its role in the prostate cancer treatment paradigm
- (2015) James L. Gulley et al. OncoImmunology
- Improved efficacy of mitoxantrone in patients with castration-resistant prostate cancer after vaccination with GM-CSF-transduced allogeneic prostate cancer cells
- (2015) Joyce M. van Dodewaard-de Jong et al. OncoImmunology
- Trial Watch—Immunostimulation with cytokines in cancer therapy
- (2015) Erika Vacchelli et al. OncoImmunology
- Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma
- (2015) Cristian Capasso et al. OncoImmunology
- Gemcitabine enhances antitumor efficacy of recombinant lipoimmunogen-based immunotherapy
- (2015) Li-Sheng Chang et al. OncoImmunology
- Trial Watch—Oncolytic viruses and cancer therapy
- (2015) Jonathan Pol et al. OncoImmunology
- Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses
- (2014) M Takagi-Kimura et al. CANCER GENE THERAPY
- MicroRNA-mediated multi-tissue detargeting of oncolytic measles virus
- (2014) M A Baertsch et al. CANCER GENE THERAPY
- A Vaccinia Virus Armed with Interleukin-10 Is a Promising Therapeutic Agent for Treatment of Murine Pancreatic Cancer
- (2014) L. S. Chard et al. CLINICAL CANCER RESEARCH
- Safety and Efficacy of VCN-01, an Oncolytic Adenovirus Combining Fiber HSG-Binding Domain Replacement with RGD and Hyaluronidase Expression
- (2014) A. Rodriguez-Garcia et al. CLINICAL CANCER RESEARCH
- Oncolytic vaccinia virus demonstrates antiangiogenic effects mediated by targeting of VEGF
- (2014) Weizhou Hou et al. INTERNATIONAL JOURNAL OF CANCER
- Prospective Randomized Phase 2 Trial of Intensity Modulated Radiation Therapy With or Without Oncolytic Adenovirus-Mediated Cytotoxic Gene Therapy in Intermediate-Risk Prostate Cancer
- (2014) Svend O. Freytag et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Oncolytic Activity of Avian Influenza Virus in Human Pancreatic Ductal Adenocarcinoma Cell Lines
- (2014) S. B. Kasloff et al. JOURNAL OF VIROLOGY
- Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers
- (2014) Yuan Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- From Scourge to Cure: Tumour-Selective Viral Pathogenesis as a New Strategy against Cancer
- (2014) Carolina S. Ilkow et al. PLoS Pathogens
- Trial Watch
- (2014) Fernando Aranda et al. OncoImmunology
- Trial Watch
- (2014) Fernando Aranda et al. OncoImmunology
- Two is better than one: Complementing oncolytic virotherapy with gemcitabine to potentiate antitumor immune responses
- (2014) Shashi Gujar et al. OncoImmunology
- Trial Watch:
- (2014) Jonathan Pol et al. OncoImmunology
- Consensus guidelines for the detection of immunogenic cell death
- (2014) Oliver Kepp et al. OncoImmunology
- Trial Watch
- (2014) Erika Vacchelli et al. OncoImmunology
- Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans
- (2013) C. J. Breitbach et al. CANCER RESEARCH
- Oncolytic Virotherapy Trials--Letter
- (2013) A. Hemminki et al. CLINICAL CANCER RESEARCH
- Oncolytic Virotherapy
- (2013) Daniel Y. Sze et al. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- Functional Cloning of Recurrence-specific Antigens Identifies Molecular Targets to Treat Tumor Relapse
- (2013) Nicolas Boisgerault et al. MOLECULAR THERAPY
- Oncolytic Virotherapy and Immunogenic Cancer Cell Death: Sharpening the Sword for Improved Cancer Treatment Strategies
- (2013) Samuel T Workenhe et al. MOLECULAR THERAPY
- Maraba Virus as a Potent Oncolytic Vaccine Vector
- (2013) Jonathan G Pol et al. MOLECULAR THERAPY
- Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy
- (2013) S. T. Workenhe et al. Cancer Immunology Research
- Trial watch
- (2013) Erika Vacchelli et al. OncoImmunology
- Trial watch
- (2013) Erika Vacchelli et al. OncoImmunology
- Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8+T-cell responses to anticancer vaccines
- (2013) Byram W Bridle et al. OncoImmunology
- Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: targeted delivery of the therapeutic payload in an orthotopic brain tumor model
- (2012) B Thaci et al. CANCER GENE THERAPY
- Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer
- (2012) D. M. Rommelfanger et al. CANCER RESEARCH
- Seroprevalence of neutralizing antibodies to human adenovirus type 5 in healthy adults in China
- (2012) Bin Yu et al. JOURNAL OF MEDICAL VIROLOGY
- Attenuation of Semliki Forest Virus Neurovirulence by MicroRNA-Mediated Detargeting
- (2012) E. Ylosmaki et al. JOURNAL OF VIROLOGY
- Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma
- (2012) Jose Pulido et al. NATURE BIOTECHNOLOGY
- Potent and Specific Antitumor Effect for Colorectal Cancer by CEA and Rb Double Regulated Oncolytic Adenovirus Harboring ST13 Gene
- (2012) Xiumei Zhou et al. PLoS One
- Trial Watch: Monoclonal antibodies in cancer therapy
- (2012) Lorenzo Galluzzi et al. OncoImmunology
- Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
- (2011) N. Obermajer et al. BLOOD
- COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells
- (2011) M. Fujita et al. CANCER RESEARCH
- Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ
- (2011) Byung-Jae Lee et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- ICP34.5 Protein of Herpes Simplex Virus Facilitates the Initiation of Protein Translation by Bridging Eukaryotic Initiation Factor 2α (eIF2α) and Protein Phosphatase 1
- (2011) Yapeng Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Oncolytic Specificity of Newcastle Disease Virus Is Mediated by Selectivity for Apoptosis-Resistant Cells
- (2011) M. Mansour et al. JOURNAL OF VIROLOGY
- Targeting Tumor Vasculature With an Oncolytic Virus
- (2011) Caroline J Breitbach et al. MOLECULAR THERAPY
- Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
- (2011) Caroline J. Breitbach et al. NATURE
- Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors
- (2011) Timothy Kottke et al. NATURE MEDICINE
- Potentiating Cancer Immunotherapy Using an Oncolytic Virus
- (2010) Byram W Bridle et al. MOLECULAR THERAPY
- Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus
- (2010) Jan Brun et al. MOLECULAR THERAPY
- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
- (2010) Philip W. Kantoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways
- (2009) Shruthi Naik et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells
- (2009) Moses K. Donkor et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Establishment of biological and pharmacokinetic assays of telomerase-specific replication-selective adenovirus
- (2008) Yuuri Hashimoto et al. CANCER SCIENCE
- Oncolytic viruses: a novel form of immunotherapy
- (2008) Robin J Prestwich et al. Expert Review of Anticancer Therapy
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