Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

Efficacy of Systemically Administered Oncolytic Vaccinia Virotherapy for Malignant Gliomas Is Enhanced by Combination Therapy with Rapamycin or Cyclophosphamide

(2009) X. Q. Lun et al.   CLINICAL CANCER RESEARCH

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Enhancement of Oncolytic Properties of Recombinant Newcastle Disease Virus Through Antagonism of Cellular Innate Immune Responses

(2009) Dmitriy Zamarin et al.   MOLECULAR THERAPY

Ras Signaling Influences Permissiveness of Malignant Peripheral Nerve Sheath Tumor Cells to Oncolytic Herpes

(2008) Faris Farassati et al.   AMERICAN JOURNAL OF PATHOLOGY

Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells

(2008) J Altomonte et al.   CANCER GENE THERAPY

Oncolytic Vesicular Stomatitis Viruses Are Potent Agents for Intravesical Treatment of High-Risk Bladder Cancer

(2008) B. A. Hadaschik et al.   CANCER RESEARCH

Autophagy and viral neurovirulence

(2008) Anthony Orvedahl et al.   CELLULAR MICROBIOLOGY

MDA5/RIG-I and virus recognition

(2008) Osamu Takeuchi et al.   CURRENT OPINION IN IMMUNOLOGY

Gene therapy progress and prospects cancer: oncolytic viruses

(2008) T-C Liu et al.   GENE THERAPY

rVSV(MΔ51)-M3 Is an Effective and Safe Oncolytic Virus for Cancer Therapy

(2008) Lan Wu et al.   HUMAN GENE THERAPY

Inhibition of interferon induction and signaling by paramyxoviruses

(2008) Judith M. Fontana et al.   IMMUNOLOGICAL REVIEWS

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Adenoviruses: update on structure and function

(2008) W. C. Russell   JOURNAL OF GENERAL VIROLOGY

Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial

(2008) Byeong-Ho Park et al.   LANCET ONCOLOGY

Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses

(2008) Kiyohiro Takahasi et al.   MOLECULAR CELL

Inhibition of the IFN-β Response in Hepatocellular Carcinoma by Alternative Spliced Isoform of IFN Regulatory Factor-3

(2008) Sabrina Marozin et al.   MOLECULAR THERAPY

MicroRNAs and the Regulation of Vector Tropism

(2008) Elizabeth J Kelly et al.   MOLECULAR THERAPY

Phase Ib Trial of Mutant Herpes Simplex Virus G207 Inoculated Pre-and Post-tumor Resection for Recurrent GBM

(2008) James M Markert et al.   MOLECULAR THERAPY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Engineering microRNA responsiveness to decrease virus pathogenicity

(2008) Elizabeth J Kelly et al.   NATURE MEDICINE

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

(2008) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of interferon signaling by the C and V proteins from attenuated and wild-type strains of measles virus

(2008) Judith M. Fontana et al.   VIROLOGY

Inhibition of IFN-α/β signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2

(2008) Grégory Caignard et al.   VIROLOGY

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY

Exponential Enhancement of Oncolytic Vesicular Stomatitis Virus Potency by Vector-mediated Suppression of Inflammatory Responses In Vivo

(2007) Jennifer Altomonte et al.   MOLECULAR THERAPY