The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features

Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

(2017) Michael A. DeJesus et al.   mBio

The function of the DegP (HtrA) protein: Protease versus chaperone

(2016) Zengyi Chang   IUBMB LIFE

Homogeneity and heterogeneity in amylase production by Bacillus subtilis under different growth conditions

(2016) Tina N. Ploss et al.   Microbial Cell Factories

Distinct 3D Architecture and Dynamics of the Human HtrA2(Omi) Protease and Its Mutated Variants

(2016) Artur Gieldon et al.   PLoS One

Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States

(2015) Alexander Schubert et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli

(2015) Tomasz Koper et al.   PLoS One

A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

(2015) Anna K. de Regt et al.   STRUCTURE

Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains

(2015) Przemyslaw Glaza et al.   PLoS One

Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress

(2014) S. Kim et al.   GENES & DEVELOPMENT

A Structural Portrait of the PDZ Domain Family

(2014) Andreas Ernst et al.   JOURNAL OF MOLECULAR BIOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities

(2014) Harmeet Singh et al.   PLoS One

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Emerging Roles of HTRA1 in Musculoskeletal Disease

(2013) André Nicki Tiaden et al.   AMERICAN JOURNAL OF PATHOLOGY

Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

(2013) Fei Ye et al.   BIOCHEMICAL JOURNAL

HtrA Protease Family as Therapeutic Targets

(2013) Joanna Skorko-Glonek et al.   CURRENT PHARMACEUTICAL DESIGN

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

(2013) Teresa Cortes et al.   Cell Reports

Use of knowledge-based restraints inphenix.refineto improve macromolecular refinement at low resolution

(2012) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The family of Deg/HtrA proteases in plants

(2012) Holger Schuhmann et al.   BMC PLANT BIOLOGY

Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response

(2012) Guido Hansen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Plasticity of PDZ domains in ligand recognition and signaling

(2012) Ylva Ivarsson   FEBS LETTERS

Crystal Structure ofArabidopsisDeg2 Protein Reveals an Internal PDZ Ligand Locking the Hexameric Resting State

(2012) Renhua Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

(2012) Hélène Malet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HtrA3 as an Early Marker for Preeclampsia: Specific Monoclonal Antibodies and Sensitive High-Throughput Assays for Serum Screening

(2012) Kemperly Dynon et al.   PLoS One

Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Functional Analysis of HtrA1 and Its Subdomains

(2012) Charles Eigenbrot et al.   STRUCTURE

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

HtrA is a major virulence determinant of Bacillus anthracis

(2011) Theodor Chitlaru et al.   MOLECULAR MICROBIOLOGY

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HtrA-Like Serine Protease PepD Interacts with and Modulates the Mycobacterium tuberculosis 35-kDa Antigen Outer Envelope Protein

(2011) Mark J. White et al.   PLoS One

Characterization of the Structure and Function of Escherichia coli DegQ as a Representative of the DegQ-like Proteases of Bacterial HtrA Family Proteins

(2011) Xiao-chen Bai et al.   STRUCTURE

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PDZ domains and their binding partners: structure, specificity, and modification

(2010) Ho-Jin Lee et al.   Cell Communication and Signaling

PepD Participates in the Mycobacterial Stress Response Mediated through MprAB and SigE

(2010) M. J. White et al.   JOURNAL OF BACTERIOLOGY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism

(2009) Jungsan Sohn et al.   STRUCTURE

Structure and Function of the Virulence-Associated High-Temperature Requirement A ofMycobacterium tuberculosis†‡

(2008) Nilofar N. MohamedMohaideen et al.   BIOCHEMISTRY