Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages

(2011) Seokhee Kim et al.   CELL

Role of the Periplasmic Chaperones Skp, SurA, and DegQ in Outer Membrane Protein Biogenesis in Neisseria meningitidis

(2011) E. B. Volokhina et al.   JOURNAL OF BACTERIOLOGY

Molecular Adaptation of the DegQ Protease to Exert Protein Quality Control in the Bacterial Cell Envelope

(2011) Justyna Sawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Substrate-induced remodeling of the active site regulates human HTRA1 activity

(2011) Linda Truebestein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies

(2011) R. Wrase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

(2010) Melisa Merdanovic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues

(2010) Tobias Krojer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin

(2010) Inés G Muñoz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HtrA Serine Proteases as Potential Therapeutic Targets in Cancer

(2009) Jeremy Chien et al.   CURRENT CANCER DRUG TARGETS

Chaperonin complex with a newly folded protein encapsulated in the folding chamber

(2009) D. K. Clare et al.   NATURE

Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control

(2009) Q.-T. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteases in bacterial pathogenesis

(2009) Hanne Ingmer et al.   RESEARCH IN MICROBIOLOGY

Structural basis for the regulated protease and chaperone function of DegP

(2008) Tobias Krojer et al.   NATURE

Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins

(2008) J. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Structure Fitting and Refinement Guided by Cryo-EM Density

(2008) Maya Topf et al.   STRUCTURE