Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-08-24
DOI
10.1038/s41467-018-05877-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biosynthesis of the 15-Membered Ring Depsipeptide Neoantimycin
- (2018) Will Skyrud et al. ACS Chemical Biology
- Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin
- (2018) Yuan Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Piecing together nonribosomal peptide synthesis
- (2018) Janice M Reimer et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- De novo design and engineering of non-ribosomal peptide synthetases
- (2017) Kenan A. J. Bozhüyük et al. Nature Chemistry
- ClusterCAD: a computational platform for type I modular polyketide synthase design
- (2017) Clara H Eng et al. NUCLEIC ACIDS RESEARCH
- Diversity oriented biosynthesis via accelerated evolution of modular gene clusters
- (2017) Aleksandra Wlodek et al. Nature Communications
- Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering
- (2016) Irina Koryakina et al. ACS Chemical Biology
- On-line enzymatic tailoring of polyketides and peptides in thiotemplate systems
- (2016) Srividhya Sundaram et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Calyculin: Nature's way of making the sponge-derived cytotoxin
- (2016) Toshiyuki Wakimoto et al. NATURAL PRODUCT REPORTS
- Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities
- (2016) Joyce Liu et al. NATURAL PRODUCT REPORTS
- Recent advances in the biosynthesis of unusual polyketide synthase substrates
- (2016) Lauren Ray et al. NATURAL PRODUCT REPORTS
- Structural elements of an NRPS cyclization domain and its intermodule docking domain
- (2016) Daniel P. Dowling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production
- (2016) Satoshi Yuzawa et al. ACS Synthetic Biology
- Screening and Engineering the Synthetic Potential of Carboxylating Reductases from Central Metabolism and Polyketide Biosynthesis
- (2015) Dominik M. Peter et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Freedom and Constraint in Engineered Noncolinear Polyketide Assembly Lines
- (2015) Yuki Sugimoto et al. CHEMISTRY & BIOLOGY
- The structural biology of biosynthetic megaenzymes
- (2015) Kira J Weissman Nature Chemical Biology
- Rational Design of Modular Polyketide Synthases: Morphing the Aureothin Pathway into a Luteoreticulin Assembly Line
- (2014) Yuki Sugimoto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structure of a modular polyketide synthase
- (2014) Somnath Dutta et al. NATURE
- De novo biosynthesis of terminal alkyne-labeled natural products
- (2014) Xuejun Zhu et al. Nature Chemical Biology
- Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont
- (2014) Toshiyuki Wakimoto et al. Nature Chemical Biology
- A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis
- (2014) Marnix H. Medema et al. PLoS Computational Biology
- Multiplexing of Combinatorial Chemistry in Antimycin Biosynthesis: Expansion of Molecular Diversity and Utility
- (2013) Yan Yan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical variation from the neoantimycin depsipeptide assembly line
- (2013) Xiang Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Engineering polyketide synthases and nonribosomal peptide synthetases
- (2013) Gavin J Williams CURRENT OPINION IN STRUCTURAL BIOLOGY
- Chemical and biosynthetic evolution of the antimycin-type depsipeptides
- (2013) Stephanie A. Vanner et al. Molecular BioSystems
- Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites
- (2013) Mamoru Komatsu et al. ACS Synthetic Biology
- Enzymatic Synthesis of Dilactone Scaffold of Antimycins
- (2012) Moriah Sandy et al. ACS Chemical Biology
- Enzyme-Directed Mutasynthesis: A Combined Experimental and Theoretical Approach to Substrate Recognition of a Polyketide Synthase
- (2012) Uschi Sundermann et al. ACS Chemical Biology
- Bcl-2 Inhibitors: Emerging Drugs in Cancer Therapy
- (2012) C. Bodur et al. CURRENT MEDICINAL CHEMISTRY
- Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production
- (2012) Yan Yan et al. ORGANIC LETTERS
- Beyond ethylmalonyl-CoA: The functional role of crotonyl-CoAcarboxylase/reductase homologs in expanding polyketide diversity
- (2011) Micheal C. Wilson et al. NATURAL PRODUCT REPORTS
- Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase
- (2010) S. Kapur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
- (2010) M. Komatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways
- (2008) Elizabeth S. Sattely et al. NATURAL PRODUCT REPORTS
- Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection
- (2008) TuAnh Nguyen et al. NATURE BIOTECHNOLOGY
- Evolution of polyketide synthases in bacteria
- (2008) C. P. Ridley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now