Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont

An environmental bacterial taxon with a large and distinct metabolic repertoire

(2014) Micheal C. Wilson et al.   NATURE

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

(2013) Robin Teufel et al.   NATURE

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis

(2013) Anthony S Haines et al.   Nature Chemical Biology

Baeyer–Villiger Oxidation of Acyl Carrier Protein-Tethered Thioester to Acyl Carrier Protein-Linked Thiocarbonate Catalyzed by a Monooxygenase Domain in FR901464 Biosynthesis

(2013) Man-Cheng Tang et al.   ACS Catalysis

Calyxamides A and B, Cytotoxic Cyclic Peptides from the Marine Sponge Discodermia calyx

(2012) Miki Kimura et al.   JOURNAL OF NATURAL PRODUCTS

Porphyrins from a metagenomic library of the marine sponge Discodermia calyx

(2012) Rui He et al.   Molecular BioSystems

Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis

(2012) U. Kaasalainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome

(2011) Tushar Shakya et al.   CHEMISTRY & BIOLOGY

Mutagenesis of a Modular Polyketide Synthase Enoylreductase Domain Reveals Insights into Catalysis and Stereospecificity

(2010) David H. Kwan et al.   ACS Chemical Biology

The Final Steps of Bacillaene Biosynthesis in Bacillus amyloliquefaciens FZB42: Direct Evidence for β,γ Dehydration by a trans-Acyltransferase Polyketide Synthase

(2010) Jana Moldenhauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding of diarrheic shellfish poisoning toxins to okadaic acid binding proteins purified from the sponge Halichondria okadai

(2010) Keiichi Konoki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

TagCleaner: Identification and removal of tag sequences from genomic and metagenomic datasets

(2010) Robert Schmieder et al.   BMC BIOINFORMATICS

Calyculins and Related Marine Natural Products as Serine- Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C

(2010) Annika Fagerholm et al.   Marine Drugs

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

Functionally Distinct Modules Operate Two Consecutive α,β→β,γ Double-Bond Shifts in the Rhizoxin Polyketide Assembly Line

(2009) Björn Kusebauch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ABySS: A parallel assembler for short read sequence data

(2009) J. T. Simpson et al.   GENOME RESEARCH

Activated Chemical Defense in Marine Sponges—a Case Study on Aplysinella rhax

(2008) Carsten Thoms et al.   JOURNAL OF CHEMICAL ECOLOGY

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY