- Home
- Publications
- Publication Search
- Publication Details
Title
Dissecting Alzheimer disease in Down syndrome using mouse models
Authors
Keywords
-
Journal
Frontiers in Behavioral Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-10-14
DOI
10.3389/fnbeh.2015.00268
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hippocampal Network Alterations in Alzheimer's Disease and Down Syndrome: From Structure to Therapy
- (2018) Martha Millan Sanchez et al. JOURNAL OF ALZHEIMERS DISEASE
- A Noradrenergic Lesion Exacerbates Neurodegeneration in a Down Syndrome Mouse Model
- (2018) Jason Lockrow et al. JOURNAL OF ALZHEIMERS DISEASE
- Oxidative Stress and Memory Decline in Adults with Down Syndrome: Longitudinal Study
- (2018) Panagiotis Zis et al. JOURNAL OF ALZHEIMERS DISEASE
- Early Endosomal Abnormalities and Cholinergic Neuron Degeneration in Amyloid-β Protein Precursor Transgenic Mice
- (2018) Jennifer H.K. Choi et al. JOURNAL OF ALZHEIMERS DISEASE
- Synaptophysin and Synaptojanin-1 in Down Syndrome are Differentially Affected by Alzheimer's Disease
- (2018) Sarah B. Martin et al. JOURNAL OF ALZHEIMERS DISEASE
- Serum MHPG Strongly Predicts Conversion to Alzheimer's Disease in Behaviorally Characterized Subjects with Down Syndrome
- (2018) Alain D. Dekker et al. JOURNAL OF ALZHEIMERS DISEASE
- Alzheimer's Disease and Down Syndrome Rodent Models Exhibit Audiogenic Seizures
- (2017) Cara J. Westmark et al. JOURNAL OF ALZHEIMERS DISEASE
- Astrocytes in physiological aging and Alzheimer’s disease
- (2016) J.J. Rodríguez-Arellano et al. NEUROSCIENCE
- Accelerated epigenetic aging in Down syndrome
- (2015) Steve Horvath et al. AGING CELL
- Down syndrome and Alzheimer's disease: Common pathways, common goals
- (2015) Dean Hartley et al. Alzheimers & Dementia
- Florbetapir PET, FDG PET, and MRI in Down syndrome individuals with and without Alzheimer's dementia
- (2015) Marwan N. Sabbagh et al. Alzheimers & Dementia
- Increased CSF A during the very early phase of cerebral A deposition in mouse models
- (2015) L. F. Maia et al. EMBO Molecular Medicine
- A novel DYRK1A (Dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologiesin vitro
- (2015) Séverine Coutadeur et al. JOURNAL OF NEUROCHEMISTRY
- Designer Receptors Enhance Memory in a Mouse Model of Down Syndrome
- (2015) A. M. Fortress et al. JOURNAL OF NEUROSCIENCE
- Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome
- (2015) Jonathan Witton et al. NATURE NEUROSCIENCE
- A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
- (2015) Frances K. Wiseman et al. NATURE REVIEWS NEUROSCIENCE
- The storm before the quiet: neuronal hyperactivity and Aβ in the presymptomatic stages of Alzheimer's disease
- (2015) Anita Stargardt et al. NEUROBIOLOGY OF AGING
- Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome
- (2015) Nicole Schupf et al. NEUROBIOLOGY OF AGING
- Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain
- (2015) Pritika J. Narayan et al. NEUROBIOLOGY OF DISEASE
- Seizures in Alzheimer’s disease
- (2015) H.A. Born NEUROSCIENCE
- Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration
- (2015) Aoife Murray et al. STEM CELLS
- Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System
- (2015) Joshua G. Hunsberger et al. STEM CELLS AND DEVELOPMENT
- N-butylidenephthalide Attenuates Alzheimer's Disease-Like Cytopathy in Down Syndrome Induced Pluripotent Stem Cell-Derived Neurons
- (2015) Chia-Yu Chang et al. Scientific Reports
- APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons
- (2015) Steven Moore et al. Cell Reports
- Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Hspa13-App Region
- (2015) Véronique Brault et al. PLoS Genetics
- Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease
- (2015) Georg M Kerbler et al. NeuroImage-Clinical
- DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease
- (2015) Harriet M. Jackson et al. PLoS One
- The complexities of the pathology–pathogenesis relationship in Alzheimer disease
- (2014) Rudy J. Castellani et al. BIOCHEMICAL PHARMACOLOGY
- Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease
- (2014) Fabio Di Domenico et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dementia diagnostic criteria in Down syndrome
- (2014) Rory Sheehan et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Decreased γ-aminobutyric acid levels in the parietal region of patients with Alzheimer's disease
- (2014) Xue Bai et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity
- (2014) Yuichi Hashimoto et al. JOURNAL OF NEUROCHEMISTRY
- Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease
- (2014) H. A. Born et al. JOURNAL OF NEUROSCIENCE
- Screening of human chromosome 21 genes in the dorsolateral prefrontal cortex of individuals with Down syndrome
- (2014) XIANG-DONG KONG et al. Molecular Medicine Reports
- Domains of genome-wide gene expression dysregulation in Down’s syndrome
- (2014) Audrey Letourneau et al. NATURE
- REST and stress resistance in ageing and Alzheimer’s disease
- (2014) Tao Lu et al. NATURE
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- Polymorphisms in BACE2 may affect the age of onset Alzheimer's dementia in Down syndrome
- (2014) Kin Y. Mok et al. NEUROBIOLOGY OF AGING
- Frontal white matter integrity in adults with Down syndrome with and without dementia
- (2014) David Powell et al. NEUROBIOLOGY OF AGING
- Altered Distribution of Hippocampal Interneurons in the Murine Down Syndrome Model Ts65Dn
- (2014) Samuel Hernández-González et al. NEUROCHEMICAL RESEARCH
- Exploring Alzheimer Molecular Pathology in Down's Syndrome Cerebrospinal Fluid
- (2014) Erik Portelius et al. Neurodegenerative Diseases
- Altered Cerebrospinal Fluid Levels of Amyloid β and Amyloid Precursor-Like Protein 1 Peptides in Down’s Syndrome
- (2014) Erik Portelius et al. NEUROMOLECULAR MEDICINE
- Treating enhanced GABAergic inhibition in Down syndrome: Use of GABA α5-selective inverse agonists
- (2014) Carmen Martínez-Cué et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Epigenetics: The neglected key to minimize learning and memory deficits in Down syndrome
- (2014) Alain D. Dekker et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Early Onset Alzheimer’s Disease and Oxidative Stress
- (2014) Marco Antonio Meraz-Ríos et al. Oxidative Medicine and Cellular Longevity
- RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
- (2014) Xiulian Sun et al. PLoS One
- Age-Related Changes of Adaptive and Neuropsychological Features in Persons with Down Syndrome
- (2014) Alessandro Ghezzo et al. PLoS One
- Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease
- (2014) Linda Lee et al. Scientific Reports
- Managing the care of adults with Down's syndrome
- (2014) K. M. Jensen et al. BMJ-British Medical Journal
- Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity
- (2014) Xin Wang et al. Cell Reports
- Plasma DYRK1A as a novel risk factor for Alzheimer’s disease
- (2014) N Janel et al. Translational Psychiatry
- Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
- (2014) Scott J. Webster et al. Frontiers in Genetics
- Aging and intellectual disability: Insights from mouse models of down syndrome
- (2013) Aarti Ruparelia et al. Developmental Disabilities Research Reviews
- Atypical aging in down syndrome
- (2013) Warren B. Zigman Developmental Disabilities Research Reviews
- The population prevalence of Down’s syndrome in England and Wales in 2011
- (2013) Jianhua Wu et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice
- (2013) Chunhong Liu et al. HUMAN GENETICS
- Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome
- (2013) Xin Wang et al. NATURE MEDICINE
- Overexpression of Down syndrome cell adhesion molecule impairs precise synaptic targeting
- (2013) Vedrana Cvetkovska et al. NATURE NEUROSCIENCE
- Effects of levetiracetam, an antiepileptic drug, on memory impairments associated with aging and Alzheimer’s disease in mice
- (2013) Latha Devi et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Epigenetics of Alzheimer’s Disease and Frontotemporal Dementia
- (2013) Chendhore S. Veerappan et al. Neurotherapeutics
- Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
- (2013) Grietje Krabbe et al. PLoS One
- Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome
- (2013) Susan M. Gribble et al. PLoS One
- Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome
- (2013) Matilda A. Haas et al. PLoS One
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- The Genetics of Alzheimer Disease
- (2013) R. E. Tanzi Cold Spring Harbor Perspectives in Medicine
- The Neuropsychological Profile of Alzheimer Disease
- (2013) S. Weintraub et al. Cold Spring Harbor Perspectives in Medicine
- Clinical, Biological, and Imaging Features of Monogenic Alzheimer’s Disease
- (2013) Andrea Pilotto et al. Biomed Research International
- Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease
- (2013) Keith A. Vossel et al. JAMA Neurology
- Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
- (2012) Laure Verret et al. CELL
- Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screening
- (2012) Maria Loane et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease
- (2012) Juan Beauquis et al. EXPERIMENTAL NEUROLOGY
- OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors
- (2012) Jie Lu et al. HUMAN MOLECULAR GENETICS
- Trisomy for Synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes
- (2012) Jack-Christophe Cossec et al. HUMAN MOLECULAR GENETICS
- Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
- (2012) Katherine R. Martin et al. HUMAN MOLECULAR GENETICS
- Down's syndrome and Alzheimer's disease: towards secondary prevention
- (2012) Seth Ness et al. NATURE REVIEWS DRUG DISCOVERY
- The early events of Alzheimer's disease pathology: from mitochondrial dysfunction to BDNF axonal transport deficits
- (2012) Xuan Ye et al. NEUROBIOLOGY OF AGING
- Role of common and rare APP DNA sequence variants in Alzheimer disease
- (2012) B. V. Hooli et al. NEUROLOGY
- Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease
- (2012) Beverly M Francis et al. NEUROPSYCHOPHARMACOLOGY
- Synaptic changes in Alzheimer’s disease and its models
- (2012) J. Pozueta et al. NEUROSCIENCE
- Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
- (2012) P. E. Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted proteomics for quantification of histone acetylation in Alzheimer's disease
- (2012) Kangling Zhang et al. PROTEOMICS
- A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome
- (2012) Y. Shi et al. Science Translational Medicine
- Genetic analysis of Down syndrome facilitated by mouse chromosome engineering
- (2012) Li Zhang et al. Bioengineered
- Microglial pathology in Down syndrome
- (2011) Qing-Shan Xue et al. ACTA NEUROPATHOLOGICA
- The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Marilyn S. Albert et al. Alzheimers & Dementia
- Using Positron Emission Tomography and Carbon 11–Labeled Pittsburgh Compound B to Image Brain Fibrillar β-Amyloid in Adults With Down Syndrome
- (2011) Jennifer Landt ARCHIVES OF NEUROLOGY
- Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes
- (2011) Mireia Vilardell et al. BMC GENOMICS
- Mouse models of Alzheimer's disease
- (2011) Alicia M. Hall et al. BRAIN RESEARCH BULLETIN
- Mouse Models for Down Syndrome-Associated Developmental Cognitive Disabilities
- (2011) Chunhong Liu et al. DEVELOPMENTAL NEUROSCIENCE
- The use of mouse models to understand and improve cognitive deficits in Down syndrome
- (2011) I. Das et al. Disease Models & Mechanisms
- α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome
- (2011) Mototada Shichiri et al. FREE RADICAL BIOLOGY AND MEDICINE
- Trisomic and Allelic Differences Influence Phenotypic Variability During Development of Down Syndrome Mice
- (2011) Samantha L. Deitz et al. GENETICS
- Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation
- (2011) Xiulian Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recent rodent models for Alzheimer’s disease: clinical implications and basic research
- (2011) Nady Braidy et al. JOURNAL OF NEURAL TRANSMISSION
- Neuroinflammation in Alzheimer's disease wanes with age
- (2011) Jeroen JM Hoozemans et al. Journal of Neuroinflammation
- Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease
- (2011) C. Perez-Cruz et al. JOURNAL OF NEUROSCIENCE
- Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
- (2011) Laura G. Reinholdt et al. MAMMALIAN GENOME
- Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome
- (2011) Arnaud Duchon et al. MAMMALIAN GENOME
- Altered regulation of tau phosphorylation in a mouse model of down syndrome aging
- (2011) Olivia Sheppard et al. NEUROBIOLOGY OF AGING
- Intersectin 1 contributes to phenotypes in vivo
- (2011) Michael P. Hunter et al. NEUROREPORT
- S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors
- (2011) Jie Lu et al. PLoS One
- Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB
- (2011) Véronique Brault et al. PLoS One
- Trisomy 21 and early brain development
- (2011) Tarik F. Haydar et al. TRENDS IN NEUROSCIENCES
- In vivo effects of APP are not exacerbated by BACE2 co-overexpression: behavioural characterization of a double transgenic mouse model
- (2010) Garikoitz Azkona et al. AMINO ACIDS
- Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome
- (2010) Jason Lockrow et al. BEHAVIOURAL BRAIN RESEARCH
- Correlating familial Alzheimer’s disease gene mutations with clinical phenotype
- (2010) Natalie S Ryan et al. Biomarkers in Medicine
- Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006
- (2010) Samantha E. Parker et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice
- (2010) Tao Yu et al. BRAIN RESEARCH
- Neural Stem Cells Reduce Hippocampal Tau and Reelin Accumulation in Aged Ts65Dn down Syndrome Mice
- (2010) D. S. Kern et al. CELL TRANSPLANTATION
- Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer’s disease
- (2010) Eduardo Cumbo et al. EPILEPSY & BEHAVIOR
- A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions
- (2010) Tao Yu et al. HUMAN MOLECULAR GENETICS
- Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer’s disease
- (2010) Young Shin Ryu et al. JOURNAL OF NEUROCHEMISTRY
- Link Between DYRK1A Overexpression and Several-Fold Enhancement of Neurofibrillary Degeneration With 3-Repeat Tau Protein in Down Syndrome
- (2010) Jerzy Wegiel et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo
- (2010) Anne Eckert et al. MOLECULAR NEUROBIOLOGY
- Transgenic Mouse Models of Alzheimer's Disease
- (2010) Gregory A. Elder et al. MOUNT SINAI JOURNAL OF MEDICINE
- APP Transgenic Mice: Their Use and Limitations
- (2010) Claudia Balducci et al. NEUROMOLECULAR MEDICINE
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Communication breaks-Down: From neurodevelopment defects to cognitive disabilities in Down syndrome
- (2010) Andrea Contestabile et al. PROGRESS IN NEUROBIOLOGY
- Senile myoclonic epilepsy: Delineation of a common condition associated with Alzheimer's disease in Down syndrome
- (2010) Roberto De Simone et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease
- (2009) Wolfgang J. Streit et al. ACTA NEUROPATHOLOGICA
- Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions
- (2009) Tyler A. Kokjohn et al. Alzheimers & Dementia
- Epilepsy and Cognitive Impairments in Alzheimer Disease
- (2009) Jorge J. Palop ARCHIVES OF NEUROLOGY
- Does the learning deficit observed under an incremental repeated acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age?
- (2009) Nichole C. Sanders et al. BEHAVIOURAL BRAIN RESEARCH
- Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6brd1
- (2009) Alberto C.S. Costa et al. BEHAVIOURAL BRAIN RESEARCH
- Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease
- (2009) Nathan R. Rustay et al. BRAIN RESEARCH
- APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis
- (2009) Leslie Crews et al. Brain Structure & Function
- The role of the hippocampus in mnemonic integration and retrieval: complementary evidence from lesion and inactivation studies
- (2009) M. D. Iordanova et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2
- (2009) G. Azkona et al. GENES BRAIN AND BEHAVIOR
- Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease
- (2009) Takashi Mori et al. GLIA
- Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome
- (2009) M. Galante et al. HUMAN MOLECULAR GENETICS
- A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome
- (2009) Patricia Lopes Pereira et al. HUMAN MOLECULAR GENETICS
- Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model
- (2009) Jennifer H. K. Choi et al. JOURNAL OF NEUROCHEMISTRY
- Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease
- (2009) K Kasuga et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease
- (2009) S. Peng et al. JOURNAL OF NEUROSCIENCE
- Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1
- (2009) Pamela F Parkinson et al. Lipids in Health and Disease
- Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice
- (2009) Patricia Szot et al. NEUROSCIENCE LETTERS
- Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease
- (2009) R. Sims et al. NEUROSCIENCE LETTERS
- Aneuploidy: From a Physiological Mechanism of Variance to Down Syndrome
- (2009) Mara Dierssen et al. PHYSIOLOGICAL REVIEWS
- Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition
- (2009) Y. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Upregulation of three Drosophila homologs of human chromosome 21 genes alters synaptic function: Implications for Down syndrome
- (2009) K. T. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies
- (2009) J. O. Korbel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome
- (2008) Jerzy Wegiel et al. ACTA NEUROPATHOLOGICA
- DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome
- (2008) Claudia Canzonetta et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Cerebral amyloid angiopathy-related hemorrhage in a middle-aged patient with Down's syndrome
- (2008) Ko-Suke Naito et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Clinical and Neuropathological Features of the Arctic APP Gene Mutation Causing Early-Onset Alzheimer Disease
- (2008) Hans Basun et al. ARCHIVES OF NEUROLOGY
- Effects of the genetic background on cognitive performances of TG2576 mice
- (2008) Jean Michel Lassalle et al. BEHAVIOURAL BRAIN RESEARCH
- Sumoylation of amyloid precursor protein negatively regulates Aβ aggregate levels
- (2008) Yu-Qian Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model
- (2008) Jason Lockrow et al. EXPERIMENTAL NEUROLOGY
- Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
- (2008) Fei Liu et al. FASEB JOURNAL
- Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome
- (2008) Jianhua Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells
- (2008) Giuseppe Esposito et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo
- (2008) Braydon L. Burgess et al. JOURNAL OF LIPID RESEARCH
- Survival in Elderly Persons with Down Syndrome
- (2008) Antonia M. W. Coppus et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- INTRAFAMILIAL DIVERSITY OF PHENOTYPE ASSOCIATED WITH APP DUPLICATION
- (2008) I. Guyant-Marechal et al. NEUROLOGY
- Abnormal expression of synaptic proteins and neurotrophin-3 in the down syndrome mouse model Ts65Dn
- (2008) G. Pollonini et al. NEUROSCIENCE
- Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome
- (2008) S. V. Voronov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's disease and Down's syndrome: an in vivo MRI study
- (2008) F. Beacher et al. PSYCHOLOGICAL MEDICINE
- Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer’s disease
- (2007) Soo-Ryoon Ryoo et al. JOURNAL OF NEUROCHEMISTRY
- Translational gene mapping of cognitive decline
- (2006) Beth Wilmot et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More