DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease

Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries

(2014) Anuj Srivastava et al.   BMC GENOMICS

Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-  accumulation modifier

(2014) T. Morihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A commentary on studies presenting projections of the future prevalence of dementia

(2013) Sam Norton et al.   BMC PUBLIC HEALTH

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

(2013) Gareth R Howell et al.   Journal of Neuroinflammation

2012: A watershed year for Alzheimer’s disease research

(2013) M. Grundman et al.   Journal of Nutrition Health & Aging

Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma

(2013) Pete A. Williams et al.   PLoS One

Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease

(2013) Keith A. Vossel et al.   JAMA Neurology

Quantitative trait locus on distal chromosome 1 regulates the occurrence of spontaneous spike-wave discharges in DBA/2 mice

(2012) Thomas Bessaïh et al.   EPILEPSIA

Aberrant sodium channel activity in the complex seizure disorder ofCelf4mutant mice

(2012) Wenzhi Sun et al.   JOURNAL OF PHYSIOLOGY-LONDON

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

(2012) Reisa Sperling et al.   LANCET NEUROLOGY

The Age-related Gliosis and Accompanying Deficit in Spatial Learning are Unaffected by Dimebon

(2012) Thelma R. Cowley et al.   NEUROCHEMICAL RESEARCH

Accelerating Discovery for Complex Neurological and Behavioral Disorders Through Systems Genetics and Integrative Genomics in the Laboratory Mouse

(2012) Jason A. Bubier et al.   Neurotherapeutics

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation

(2012) Demian Obregon et al.   Nature Communications

“Untangling” Alzheimer's Disease and Epilepsy

(2012) Helen E. Scharfman   Epilepsy Currents

What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us

(2011) Nina F. Schor   ANNALS OF NEUROLOGY

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Genetic Regulatory Network Analysis forAppBased on Genetical Genomics Approach

(2010) Xusheng Wang et al.   EXPERIMENTAL AGING RESEARCH

Alzheimer's failure raises questions about disease-modifying strategies

(2010) Andy Extance   NATURE REVIEWS DRUG DISCOVERY

Seizures in Alzheimer Disease

(2009) Nikolaos Scarmeas et al.   ARCHIVES OF NEUROLOGY

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain

(2009) D.L. Vogt et al.   NEUROBIOLOGY OF AGING

An Overview of APP Processing Enzymes and Products

(2009) Vivian W. Chow et al.   NEUROMOLECULAR MEDICINE

Genetics of complex neurological disease: challenges and opportunities for modeling epilepsy in mice and rats

(2009) Wayne N. Frankel   TRENDS IN GENETICS

Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease

(2007) Davis Ryman et al.   NEUROBIOLOGY OF AGING