Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

Oscillatory Dynamics and Place Field Maps Reflect Hippocampal Ensemble Processing of Sequence and Place Memory under NMDA Receptor Control

(2014) Henrique O. Cabral et al.   NEURON

Dentate gyrus mediates cognitive function in the Ts65Dn/DnJ mouse model of down syndrome

(2013) Genevieve K. Smith et al.   HIPPOCAMPUS

Rigid firing sequences undermine spatial memory codes in a neurodegenerative mouse model

(2013) Jingheng Cheng et al.   eLife

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn

(2011) Laura G. Reinholdt et al.   MAMMALIAN GENOME

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

(2011) Arnaud Duchon et al.   MAMMALIAN GENOME

Updating hippocampal representations: CA2 joins the circuit

(2011) Matthew W. Jones et al.   TRENDS IN NEUROSCIENCES

Donepezil for treatment of cognitive dysfunction in children with Down syndrome aged 10-17

(2010) Priya S. Kishnani et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A computational theory of episodic memory formation in the hippocampus

(2010) Edmund T. Rolls   BEHAVIOURAL BRAIN RESEARCH

Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy

(2010) Jesse E Hanson et al.   BMC NEUROSCIENCE

Coordination of size and number of excitatory and inhibitory synapses results in a balanced structural plasticity along mature hippocampal CA1 dendrites during LTP

(2010) Jennifer N. Bourne et al.   HIPPOCAMPUS

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

(2010) Tao Yu et al.   HUMAN MOLECULAR GENETICS

Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of down syndrome

(2010) Victor I. Popov et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Development and validation of the Arizona Cognitive Test Battery for Down syndrome

(2010) Jamie O. Edgin et al.   Journal of Neurodevelopmental Disorders

Communication breaks-Down: From neurodevelopment defects to cognitive disabilities in Down syndrome

(2010) Andrea Contestabile et al.   PROGRESS IN NEUROBIOLOGY

Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein

(2010) Jonathan Witton et al.   Molecular Brain

Function and regulation of Dyrk1A: towards understanding Down syndrome

(2009) Joongkyu Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

(2009) Patricia Lopes Pereira et al.   HUMAN MOLECULAR GENETICS

The "Down Syndrome Critical Region" Is Sufficient in the Mouse Model to Confer Behavioral, Neurophysiological, and Synaptic Phenotypes Characteristic of Down Syndrome

(2009) N. P. Belichenko et al.   JOURNAL OF NEUROSCIENCE

Molecular basis of pharmacotherapies for cognition in Down syndrome

(2009) Katheleen J. Gardiner   TRENDS IN PHARMACOLOGICAL SCIENCES

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome

(2008) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Target-Cell Specificity of Kainate Autoreceptor and Ca2+-Store-Dependent Short-Term Plasticity at Hippocampal Mossy Fiber Synapses

(2008) R. Scott et al.   JOURNAL OF NEUROSCIENCE

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

(2008) E. Morice et al.   LEARNING & MEMORY