Accelerated epigenetic aging in Down syndrome

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

Domains of genome-wide gene expression dysregulation in Down’s syndrome

(2014) Audrey Letourneau et al.   NATURE

Obesity accelerates epigenetic aging of human liver

(2014) S. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

(2013) Meaghan J Jones et al.   BMC Medical Genomics

Atypical aging in down syndrome

(2013) Warren B. Zigman   Developmental Disabilities Research Reviews

DNA methylation, genotype and gene expression: who is driving and who is along for the ride?

(2013) Meaghan J Jones et al.   GENOME BIOLOGY

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging

(2011) David Patterson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Massive-Scale RNA-Seq Analysis of Non Ribosomal Transcriptome in Human Trisomy 21

(2011) Valerio Costa et al.   PLoS One

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Altered DNA Methylation in Leukocytes with Trisomy 21

(2010) Kristi Kerkel et al.   PLoS Genetics

Increased “absence” of telomeres may indicate Alzheimer's disease/dementia status in older individuals with Down syndrome

(2008) Edmund C. Jenkins et al.   NEUROSCIENCE LETTERS