Follicular helper T-cell memory: establishing new frontiers during antibody response

Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection

(2013) Noah J. Tubo et al.   CELL

Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype

(2013) Dirk Baumjohann et al.   IMMUNITY

Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure

(2013) Jing He et al.   IMMUNITY

Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

(2013) J. Scott Hale et al.   IMMUNITY

Bcl6 Expressing Follicular Helper CD4 T Cells Are Fate Committed Early and Have the Capacity To Form Memory

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

T Follicular Helper Cell Dynamics in Germinal Centers

(2013) Z. Shulman et al.   SCIENCE

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

T follicular helper cell diversity and plasticity

(2013) Jennifer L. Cannons et al.   TRENDS IN IMMUNOLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

IgM memory B cells: a mouse/human paradox

(2012) Claude-Agnès Reynaud et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

T-follicular helper cells survive as long-term memory cells

(2012) Jan P. Weber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Bcl6 expression specifies the T follicular helper cell program in vivo

(2012) Xindong Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

(2012) Peter T Sage et al.   NATURE IMMUNOLOGY

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

(2012) Katja Lüthje et al.   NATURE IMMUNOLOGY

SLAM Family Receptors and SAP Adaptors in Immunity

(2011) Jennifer L. Cannons et al.   Annual Review of Immunology

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells

(2011) Marion Pepper et al.   IMMUNITY

Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection

(2011) Heather D. Marshall et al.   IMMUNITY

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone

(2011) Steven M. Kerfoot et al.   IMMUNITY

Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells

(2011) Kristina T. Lu et al.   IMMUNITY

Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

(2011) Masahiro Kitano et al.   IMMUNITY

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

(2011) Laura M. Fahey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Distinct Waves of BCL6 Expression during T Follicular Helper Cell Development

(2011) D. Baumjohann et al.   JOURNAL OF IMMUNOLOGY

CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses

(2011) N. Chevalier et al.   JOURNAL OF IMMUNOLOGY

Memory CD4 T Cells That Express CXCR5 Provide Accelerated Help to B Cells

(2011) M. K. L. MacLeod et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Dendritic Cell-Restricted Antigen Presentation Initiates the Follicular Helper T Cell Program but Cannot Complete Ultimate Effector Differentiation

(2011) R. Goenka et al.   JOURNAL OF IMMUNOLOGY

Origins of CD4+ effector and central memory T cells

(2011) Marion Pepper et al.   NATURE IMMUNOLOGY

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Immune responses to influenza virus infection

(2011) J.H.C.M. Kreijtz et al.   VIRUS RESEARCH

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

(2010) Elissa K. Deenick et al.   IMMUNITY

Memory B and memory plasma cells

(2010) Taketoshi Yoshida et al.   IMMUNOLOGICAL REVIEWS

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

(2010) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism

(2010) Dimitra Zotos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The elusive identity of T follicular helper cells

(2010) Di Yu et al.   TRENDS IN IMMUNOLOGY

Lineage specification and heterogeneity of T follicular helper cells

(2009) Di Yu et al.   CURRENT OPINION IN IMMUNOLOGY

Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity

(2009) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Follicular Helper T Cells: Lineage and Location

(2009) Nicolas Fazilleau et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

(2009) Nicolas Fazilleau et al.   NATURE IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

CD4 memory T cells: What are they and what can they do?

(2009) Megan K.L. MacLeod et al.   SEMINARS IN IMMUNOLOGY

T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

(2008) Cecile King et al.   Annual Review of Immunology

A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

(2008) Alexis Vogelzang et al.   IMMUNITY

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

(2008) Max Löhning et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory CD4 T cells emerge from effector T-cell progenitors

(2008) Laurie E. Harrington et al.   NATURE

SAP-controlled T–B cell interactions underlie germinal centre formation

(2008) Hai Qi et al.   NATURE