Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

Loss of Naive T Cells and Repertoire Constriction Predict Poor Response to Vaccination in Old Primates

(2010) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

(2010) S. Khurana et al.   Science Translational Medicine

Homeostatic proliferation and survival of naïve and memory T cells

(2009) Onur Boyman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Strength of T Cell Receptor Signaling Strikes Again

(2009) Leslie J. Berg   IMMUNITY

Evidence of premature immune aging in patients thymectomized during early childhood

(2009) Delphine Sauce et al.   JOURNAL OF CLINICAL INVESTIGATION

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

(2009) Gabriela Molina et al.   Nature Chemical Biology

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects

(2009) H. Tsukamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD28− T cells: their role in the age-associated decline of immune function

(2009) Nan-ping Weng et al.   TRENDS IN IMMUNOLOGY

T cell subset-specific susceptibility to aging

(2008) Marta Czesnikiewicz-Guzik et al.   CLINICAL IMMUNOLOGY

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

(2008) Eric J. Yager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Age-Dependent Signature of Metallothionein Expression in Primary CD4 T Cell Responses Is Due to Sustained Zinc Signaling

(2008) Won-Woo Lee et al.   REJUVENATION RESEARCH