Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice

Dual-specificity phosphatases: critical regulators with diverse cellular targets

(2015) Kate I. Patterson et al.   BIOCHEMICAL JOURNAL

Cutting Edge: TGF- -Induced Expression of Foxp3 in T cells Is Mediated through Inactivation of ERK

(2014) X. Luo et al.   JOURNAL OF IMMUNOLOGY

ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis

(2013) Houpu Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of the transcriptional activity of nuclear receptors by the MEK/ERK1/2 pathway

(2012) Fabien Zassadowski et al.   CELLULAR SIGNALLING

Polar Opposites: Erk Direction of CD4 T Cell Subsets

(2012) C.-F. Chang et al.   JOURNAL OF IMMUNOLOGY

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

(2012) Guangjin Li et al.   NATURE MEDICINE

Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease

(2011) Wei Cao et al.   IMMUNITY

Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia

(2010) Olga Bermudez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice

(2010) José M. González-Navajas et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic Inhibition of MEK–ERK Signaling Enhances Th17 Differentiation

(2010) Andy Hee-Meng Tan et al.   JOURNAL OF IMMUNOLOGY

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

(2008) Stephen D. Barrett et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility

(2008) Marjorie Maillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-translational regulation of the ERK phosphatase DUSP6/MKP3 by the mTOR pathway

(2008) O Bermudez et al.   ONCOGENE