The interplay between inflammation and metabolism in rheumatoid arthritis

cFLIP is critical for oligodendrocyte protection from inflammation

(2015) D C Tanner et al.   CELL DEATH AND DIFFERENTIATION

The synergistic interaction between the calcineurin B subunit and IFN-γ enhances macrophage antitumor activity

(2015) Z Su et al.   Cell Death & Disease

FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients

(2015) M T Cencioni et al.   Cell Death & Disease

Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes

(2015) M G Sanders et al.   Cell Death & Disease

TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression

(2015) Y-W Yin et al.   Cell Death & Disease

NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair

(2015) J D Proto et al.   Cell Death & Disease

Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice

(2015) T H-P Chen et al.   Cell Death & Disease

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

Interaction of differentiated human adipocytes with macrophages leads to trogocytosis and selective IL-6 secretion

(2015) A K Sárvári et al.   Cell Death & Disease

Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation

(2015) A C Reis et al.   Cell Death & Disease

Roles of tumor suppressors in regulating tumor-associated inflammation

(2014) L Yang et al.   CELL DEATH AND DIFFERENTIATION

TAK1 control of cell death

(2014) S R Mihaly et al.   CELL DEATH AND DIFFERENTIATION

Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

(2014) J Xu et al.   CELL DEATH AND DIFFERENTIATION

RIP kinases: key decision makers in cell death and innate immunity

(2014) F Humphries et al.   CELL DEATH AND DIFFERENTIATION

A unique role for p53 in the regulation of M2 macrophage polarization

(2014) L Li et al.   CELL DEATH AND DIFFERENTIATION

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Restoration of peripheral blood natural killer and B cell levels in patients affected by rheumatoid and psoriatic arthritis during etanercept treatment

(2014) P. Conigliaro et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Correlation of oxidant status with oxidative tissue damage in patients with rheumatoid arthritis

(2014) Suhana Datta et al.   CLINICAL RHEUMATOLOGY

Insulin Resistance is Associated with Increased Concentrations of NT-proBNP in Rheumatoid Arthritis: IL-6 as a Potential Mediator

(2014) William S. Bradham et al.   INFLAMMATION

Do statins reduce the cardiovascular risk in patients with rheumatoid arthritis?

(2014) Kathrin Danninger et al.   International Journal of Rheumatic Diseases

Waist circumference based abdominal obesity may be helpful as a marker for unmet needs in patients with RA

(2014) T Uutela et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The interaction between mesenchymal stem cells and steroids during inflammation

(2014) X Chen et al.   Cell Death & Disease

Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice

(2014) F Ewald et al.   Cell Death & Disease

Zinc depletion regulates the processing and secretion of IL-1β

(2014) H Summersgill et al.   Cell Death & Disease

Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people

(2014) O Fabre et al.   Cell Death & Disease

HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype

(2014) Y Qin et al.   Cell Death & Disease

Complement C5a exacerbates acute lung injury induced through autophagy-mediated alveolar macrophage apoptosis

(2014) R Hu et al.   Cell Death & Disease

Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

(2014) P G Través et al.   Cell Death & Disease

NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation

(2014) S R Kim et al.   Cell Death & Disease

Extracellular ATP drives systemic inflammation, tissue damage and mortality

(2014) A Cauwels et al.   Cell Death & Disease

Macrophages commit postnatal endothelium-derived progenitors to angiogenesis and restrict endothelial to mesenchymal transition during muscle regeneration

(2014) P Zordan et al.   Cell Death & Disease

Systems biology of death receptor networks: live and let die

(2014) I N Lavrik   Cell Death & Disease

Bone Erosion Is Associated With Reduction of Circulating Endothelial Progenitor Cells and Endothelial Dysfunction in Rheumatoid Arthritis

(2014) Yune-Jung Park et al.   Arthritis & Rheumatology

Metabolic Profiling Predicts Response to Anti-Tumor Necrosis Factor α Therapy in Patients With Rheumatoid Arthritis

(2013) Sabrina R. Kapoor et al.   ARTHRITIS AND RHEUMATISM

Metabolomics in rheumatic diseases: The potential of an emerging methodology for improved patient diagnosis, prognosis, and treatment efficacy

(2013) Roberta Priori et al.   AUTOIMMUNITY REVIEWS

Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab

(2013) Maria Sole Chimenti et al.   CELL CYCLE

Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice

(2013) P R Hiebert et al.   CELL DEATH AND DIFFERENTIATION

Proline oxidase–adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation

(2013) D Lettieri Barbato et al.   CELL DEATH AND DIFFERENTIATION

p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene

(2013) Z He et al.   CELL DEATH AND DIFFERENTIATION

Potent and multiple regulatory actions of microglial glucocorticoid receptors during CNS inflammation

(2013) M Á Carrillo-de Sauvage et al.   CELL DEATH AND DIFFERENTIATION

Molecular Hydrogen: New Antioxidant and Anti-inflammatory Therapy for Rheumatoid Arthritis and Related Diseases

(2013) Toru Ishibashi   CURRENT PHARMACEUTICAL DESIGN

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function

(2013) Hu Zeng et al.   NATURE

Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance

(2013) T Dimitroulas et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Role of Adipokines Signaling in the Modulation of T Cells Function

(2013) Claudio Procaccini et al.   Frontiers in Immunology

Endothelial dysfunction in rheumatic autoimmune diseases

(2012) Giuseppe Murdaca et al.   ATHEROSCLEROSIS

Immunomodulation in psoriatic arthritis: Focus on cellular and molecular pathways

(2012) Maria Sole Chimenti et al.   AUTOIMMUNITY REVIEWS

Mesenchymal stem cells: a double-edged sword in regulating immune responses

(2012) W Li et al.   CELL DEATH AND DIFFERENTIATION

Risk factors for cardiovascular disease in rheumatoid arthritis

(2012) Sherine E. Gabriel et al.   CURRENT OPINION IN RHEUMATOLOGY

A novel role for RIP1 kinase in mediating TNFα production

(2012) D E Christofferson et al.   Cell Death & Disease

Remission is the goal for cardiovascular risk management in patients with rheumatoid arthritis: a cross-sectional comparative study

(2011) S. A. Provan et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-TNFα discontinuation in rheumatoid and psoriatic arthritis: Is it possible after disease remission?

(2011) Maria Sole Chimenti et al.   AUTOIMMUNITY REVIEWS

Role of the complement system in rheumatoid arthritis and psoriatic arthritis: Relationship with anti-TNF inhibitors

(2011) Eleonora Ballanti et al.   AUTOIMMUNITY REVIEWS

Extra-articular manifestations of rheumatoid arthritis: An update

(2011) Marcella Prete et al.   AUTOIMMUNITY REVIEWS

The metabolic syndrome: The crossroads between rheumatoid arthritis and cardiovascular risk

(2011) Elisa Gremese et al.   AUTOIMMUNITY REVIEWS

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

A novel signaling pathway in TNFα-induced neutrophil apoptosis

(2011) Barbara Geering et al.   CELL CYCLE

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

(2011) R Alonso et al.   CELL DEATH AND DIFFERENTIATION

Glucocorticoid-induced TNF receptor-triggered T cells are key modulators for survival/death of neural stem/progenitor cells induced by ischemic stroke

(2011) M Takata et al.   CELL DEATH AND DIFFERENTIATION

Metabolomics and Cardiovascular Biomarker Discovery

(2011) E. P. Rhee et al.   CLINICAL CHEMISTRY

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

What's new in our understanding of the role of adipokines in rheumatic diseases?

(2011) Rodolfo Gómez et al.   Nature Reviews Rheumatology

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistin is linked to inflammation, and leptin to metabolic syndrome, in women with inflammatory arthritis

(2011) P Kontunen et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Diagnostic properties of metabolic perturbations in rheumatoid arthritis

(2011) Rasmus K Madsen et al.   ARTHRITIS RESEARCH & THERAPY

Insulin resistance in rheumatoid arthritis: the impact of the anti-TNF-α therapy

(2010) Miguel A. Gonzalez-Gay et al.   Annals of the New York Academy of Sciences

Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis

(2010) Klaus W. Frommer et al.   ARTHRITIS AND RHEUMATISM

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC–MAPKs–AP-1 pathway

(2010) Y-T Wu et al.   CELL DEATH AND DIFFERENTIATION

Recent advances in the genetics of rheumatoid arthritis

(2010) Soumya Raychaudhuri   CURRENT OPINION IN RHEUMATOLOGY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Increased Prevalence of Metabolic Syndrome Associated with Rheumatoid Arthritis in Patients without Clinical Cardiovascular Disease

(2010) C. S. CROWSON et al.   JOURNAL OF RHEUMATOLOGY

Effects of Inhibition of Interleukin-6 Signalling on Insulin Sensitivity and Lipoprotein (A) Levels in Human Subjects with Rheumatoid Diseases

(2010) Olaf Schultz et al.   PLoS One

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation

(2009) Yu-Hee Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Risk of cardiovascular mortality in patients with rheumatoid arthritis: A meta-analysis of observational studies

(2008) J. Antonio Aviña-Zubieta et al.   ARTHRITIS AND RHEUMATISM

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION