Evidence that cytokines play a role in rheumatoid arthritis

Interleukin 27 attenuates collagen-induced arthritis

(2008) W Niedbala et al.   ANNALS OF THE RHEUMATIC DISEASES

Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthritis

(2008) F Brentano et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial

(2008)   ARTHRITIS AND RHEUMATISM

Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

(2008) Stanley B. Cohen et al.   ARTHRITIS AND RHEUMATISM

Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

(2008) Kiran Nistala et al.   ARTHRITIS AND RHEUMATISM

Lymphocyte-derived cytokines in inflammatory arthritis

(2008) Nicole Horwood   AUTOIMMUNITY

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

(2008) Josef S Smolen et al.   LANCET

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

(2008) Shumpei Yokota et al.   LANCET

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutralizing IL-21 and IL-15 Inhibits Pro-inflammatory Cytokine Production in Rheumatoid Arthritis

(2008) A. K. Andersson et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE