What's new in our understanding of the role of adipokines in rheumatic diseases?

Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytes

(2011) J. Conde et al.   ANNALS OF THE RHEUMATIC DISEASES

The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype

(2011) I. R. Klein-Wieringa et al.   ANNALS OF THE RHEUMATIC DISEASES

Correlation of Plasma and Synovial Fluid Adiponectin with Knee Osteoarthritis Severity

(2011) Sittisak Honsawek et al.   ARCHIVES OF MEDICAL RESEARCH

Adiponectin is a potential catabolic mediator in osteoarthritis cartilage

(2011) Eun Ha Kang et al.   ARTHRITIS RESEARCH & THERAPY

Serum Adiponectin and Vaspin Levels in Rheumatoid Arthritis

(2010) Metin Ozgen et al.   ARCHIVES OF MEDICAL RESEARCH

Adiponectin stimulates prostaglandin E2 production in rheumatoid arthritis synovial fibroblasts

(2010) Natsuko Kusunoki et al.   ARTHRITIS AND RHEUMATISM

Generalized bone loss as a predictor of three-year radiographic damage in African American patients with recent-onset rheumatoid arthritis

(2010) Jie Zhang et al.   ARTHRITIS AND RHEUMATISM

Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis

(2010) Klaus W. Frommer et al.   ARTHRITIS AND RHEUMATISM

The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis

(2010) Rajiv Gandhi et al.   CLINICAL RHEUMATOLOGY

An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness

(2010) Claudio Procaccini et al.   IMMUNITY

Pro-inflammatory high-density lipoproteins and atherosclerosis are induced in lupus-prone mice by a high-fat diet and leptin

(2010) BH Hahn et al.   LUPUS

The yin and yang of regulatory T cells and inflammation in RA

(2010) Clare A. Notley et al.   Nature Reviews Rheumatology

Regulatory T cells in obesity: the leptin connection

(2010) Giuseppe Matarese et al.   TRENDS IN MOLECULAR MEDICINE

Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression

(2010) Marie-Solange Mutabaruka et al.   ARTHRITIS RESEARCH & THERAPY

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

(2010) Stéphane Pallu et al.   ARTHRITIS RESEARCH & THERAPY

Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomised study over 21 months

(2010) Inga-Lill Engvall et al.   ARTHRITIS RESEARCH & THERAPY

Epithelial cells in fetal intestine produce chemerin to recruit macrophages

(2009) Akhil Maheshwari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Vaspin and omentin: new adipokines differentially regulated at the site of inflammation in rheumatoid arthritis

(2009) L. Senolt et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis

(2009) M Filkova et al.   ANNALS OF THE RHEUMATIC DISEASES

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

(2009) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis

(2009) Jon T. Giles et al.   ARTHRITIS AND RHEUMATISM

Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis

(2009) Young Hee Rho et al.   ARTHRITIS AND RHEUMATISM

The infrapatellar fat pad in knee osteoarthritis: An important source of interleukin-6 and its soluble receptor

(2009) Emilie Distel et al.   ARTHRITIS AND RHEUMATISM

Effects of a 6-month infliximab treatment on plasma levels of leptin and adiponectin in patients with rheumatoid arthritis

(2009) Christos S. Derdemezis et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Mouse ChemR23 Is Expressed in Dendritic Cell Subsets and Macrophages, and Mediates an Anti-Inflammatory Activity of Chemerin in a Lung Disease Model

(2009) S. Luangsay et al.   JOURNAL OF IMMUNOLOGY

Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans

(2009) V. Catalán et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Circulating Leptin and Adiponectin Concentrations During Tumor Necrosis Factor Blockade in Patients with Active Rheumatoid Arthritis

(2009) C. POPA et al.   JOURNAL OF RHEUMATOLOGY

Plasma Adiponectin in Patients with Active, Early, and Chronic Rheumatoid Arthritis Who Are Steroid- and Disease-Modifying Antirheumatic Drug-Naive Compared with Patients with Osteoarthritis and Controls

(2009) T. B. LAURBERG et al.   JOURNAL OF RHEUMATOLOGY

Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-InducedPGE2, IL-6, and IL-8 Production

(2009) Katriina Vuolteenaho et al.   MEDIATORS OF INFLAMMATION

Regulation of Serum Amyloid A3 (SAA3) in Mouse Colonic Epithelium and Adipose Tissue by the Intestinal Microbiota

(2009) Christopher S. Reigstad et al.   PLoS One

Interleukin-1ß induces the novel adipokine chemerin in adipocytes in vitro

(2009) Susan Kralisch et al.   REGULATORY PEPTIDES

Adiponectin and leptin serum concentrations in patients with rheumatoid arthritis

(2009) Bożena Targońska-Stępniak et al.   RHEUMATOLOGY INTERNATIONAL

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators

(2009) Hyun-Mi Choi et al.   ARTHRITIS RESEARCH & THERAPY

Dexamethasone-induced expression of the glucocorticoid response gene lipocalin 2 in chondrocytes

(2008) H. C. Owen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Proteomic characterization of mouse cartilage degradation in vitro

(2008) Richard Wilson et al.   ARTHRITIS AND RHEUMATISM

Crucial role of visfatin/pre–B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis

(2008) Marjolaine Gosset et al.   ARTHRITIS AND RHEUMATISM

Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts

(2008) Kanako Kitahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anemia upregulates lipocalin 2 in the liver and serum

(2008) Wenlei Jiang et al.   BLOOD CELLS MOLECULES AND DISEASES

Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-κB/p300 binding in human synovial fibroblasts

(2008) Kwok-Man Tong et al.   CELLULAR SIGNALLING

Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction

(2008) Kosuke Ebina et al.   CLINICAL RHEUMATOLOGY

The adipokine SAA3 is induced by interleukin-1β in mouse adipocytes

(2008) Grit Sommer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Lipocalin-2 is induced by interleukin-1β in murine adipocytes in vitro

(2008) Grit Sommer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes

(2008) R. Lago et al.   OSTEOARTHRITIS AND CARTILAGE

Resistin is elevated following traumatic joint injury and causes matrix degradation and release of inflammatory cytokines from articular cartilage in vitro

(2008) J.H. Lee et al.   OSTEOARTHRITIS AND CARTILAGE

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

(2008) Nathalie Busso et al.   PLoS One

Resistin in serum is associated with higher levels of IL-1Ra in post-menopausal women with rheumatoid arthritis

(2008) H. Forsblad d'Elia et al.   RHEUMATOLOGY