The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

Total Synthesis of (−)-Xylogranatopyridine B via a Palladium-Catalyzed Oxidative Stannylation of Enones

(2018) Alexander W. Schuppe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spectroscopic Studies of the Chan–Lam Amination: A Mechanism-Inspired Solution to Boronic Ester Reactivity

(2017) Julien C. Vantourout et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances on the Application of Electrocyclic Reactions in Complex Natural Product Synthesis

(2017) Ming Bian et al.   SYNTHESIS-STUTTGART

Highly reactive “RIKEN click” probe for glycoconjugation on lysines

(2017) Regina Sibgatullina et al.   TETRAHEDRON LETTERS

Total Synthesis of the Hamigerans

(2016) Xiaojun Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Evolution of Ageladine A through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation

(2016) Takayuki Iwata et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Straightforward Synthesis of 5-Methylaaptamine from Eugenol, Employing a 6π-Electrocyclization Reaction of a 1-Azatriene

(2016) Daniel A. Heredia et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (−)-Carinatine A and (+)-Lycopladine A

(2016) Lingxing Meng   JOURNAL OF ORGANIC CHEMISTRY

Amide α,β-Dehydrogenation Using Allyl-Palladium Catalysis and a Hindered Monodentate Anilide

(2016) Yifeng Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Luotonin A and Rutaecarpine from an Aldimine via the Designed Cyclization

(2016) Se Hyun Kwon et al.   ORGANIC LETTERS

Synthetic Studies of Bioactive Heterocyclic Natural Products and Fused Heterocyclic Compounds Based on the Thermal Electrocyclic or Azaelectocyclic Reaction of 6π-Electron or Aza-6π-electron Systems

(2016) Satoshi Hibino   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Synthesis ofent-Ketorfanol via a C-H Alkenylation/Torquoselective 6π Electrocyclization Cascade

(2015) Eric M. Phillips et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-Enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT)

(2015) Adrian Ortiz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of nucleophilic substitution of hydrogen in nitroarenes to the chemistry of indoles

(2015) Mieczysław Mąkosza et al.   Chemistry of Heterocyclic Compounds

Designing New Analogs for Streamlining the Structure of Cytotoxic Lamellarin Natural Products

(2015) Kassrin Tangdenpaisal et al.   Chemistry-An Asian Journal

Neocryptolepine: A Promising Indoloisoquinoline Alkaloid with Interesting Biological Activity. Evaluation of the Drug and its Most Relevant Analogs

(2015) Enrique Larghi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Preparation of Pyranose-Based ThioimidateN-Oxides (TINOs)

(2015) Stéphanie Marquès et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of Zwitterionic Indole Alkaloids, Flavocarpine and Dihydrovincarpine, by Extended Method for Substituted Pyridine Synthesis through Azaelectrocyclization

(2015) Toyoharu Kobayashi et al.   HETEROCYCLES

Synthesis of Lamellarin D Trimethyl Ether and Lamellarin H via 6π-Electrocyclization

(2015) Clemes Dialer et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed α,β-Dehydrogenation of Esters and Nitriles

(2015) Yifeng Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anticancer Properties of Lamellarins

(2015) Christian Bailly   Marine Drugs

Highly Torquoselective Electrocyclizations and Competing 1,7-Hydrogen Shifts of 1-Azatrienes with Silyl Substitution at the Allylic Carbon

(2015) Zhi-Xiong Ma et al.   ORGANIC LETTERS

Redox Cycloisomerization Approach to 1,2-Dihydropyridines

(2015) Barry M. Trost et al.   ORGANIC LETTERS

Azaelectrocyclization on cell surface: convenient and general approach to chemical biology research

(2015) Akihiro Ogura et al.   TETRAHEDRON

Simple synthesis 11-substituted norcryptotackieine derivatives

(2015) Michał Nowacki et al.   RSC Advances

Regio- and Stereoselective 1,2-Dihydropyridine Alkylation/Addition Sequence for the Synthesis of Piperidines with Quaternary Centers

(2014) Simon Duttwyler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduced Chemical Mechanism of n-Heptane for Combustion and NOx Emission Prediction Under Diesel Engine

(2014) Ruifeng Gao et al.   ASIAN JOURNAL OF CHEMISTRY

Mild, Stereoselective, and Highly Efficient Synthesis ofN-Acylhydrazones Mediated by CeCl3·7H2O in a Broad Range of Solvents

(2014) José Maurício dos Santos Filho   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Neocryptolepine (Cryprotackieine), A Unique Bioactive Natural Product: Isolation, Synthesis, and Profile of Its Biological Activity

(2014) Andrea B. J. Bracca et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The First Total Synthesis of the Antiplasmodial Alkaloid (±)-Cassiarin C Based on a Microwave-Assisted Thermal Azaelectrocyclic Reaction

(2014) Satoshi Hibino et al.   HETEROCYCLES

One-Pot Synthesis of Pyrrole-2-carboxylates and -carboxamides via an Electrocyclization/Oxidation Sequence

(2014) Dennis Imbri et al.   JOURNAL OF ORGANIC CHEMISTRY

General Synthesis of Substituted 1,2-Dihydropyridines

(2014) David Tejedor et al.   JOURNAL OF ORGANIC CHEMISTRY

The Nitrogenous Hamigerans: Unusual Amino Acid-Derivatized Aromatic Diterpenoid Metabolites from the New Zealand Marine Sponge Hamigera tarangaensis

(2014) Jonathan D. Dattelbaum et al.   JOURNAL OF ORGANIC CHEMISTRY

Another Facet to the Anticancer Response to Lamellarin D: Induction of Cellular Senescence through Inhibition of Topoisomerase I and Intracellular Ros Production

(2014) Caroline Ballot et al.   Marine Drugs

Synthetic Approaches to the Lamellarins—A Comprehensive Review

(2014) Dennis Imbri et al.   Marine Drugs

A concise formation of N-substituted 3,4-diarylpyrroles – synthesis and cytotoxic activity

(2014) Maxim Egorov et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Preparative Synthesis of Highly Substituted Tetrahydropyridines via a Rh(I)-Catalyzed C–H Functionalization Sequence

(2014) Tehetena Mesganaw et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Convergent Synthesis of Diverse Tetrahydropyridines via Rh(I)-Catalyzed C–H Functionalization Sequences

(2014) Tehetena Mesganaw et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Bioactive rearranged limonoids from the Chinese mangrove Xylocarpus granatum Koenig

(2014) Zhen-Fang Zhou et al.   TETRAHEDRON

Synthesis of 2,6-diaryl-1,2-dihydropyridines through a 6π-electrocyclization of N-sulfonylazatrienes

(2014) Diana I.S.P. Resende et al.   TETRAHEDRON LETTERS

Total Synthesis of the Biscarbazole Alkaloids Murrafoline A-D by a Domino Sonogashira Coupling/Claisen Rearrangement/Electrocyclization Reaction

(2013) V. Pavan Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Whole-body imaging of tumor cells by azaelectrocyclization: Visualization of metastasis dependence on glycan structure

(2013) Katsunori Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cascade Syntheses Routes to the Centrocountins

(2013) Vincent Eschenbrenner-Lux et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Total Synthesis of 1,3-Disubstituted β-Carboline Alkaloids, (-)-Dichotomine A and (+)-Dichotomide II

(2013) Shinji Tagawa et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-Pot Asymmetric 6π-Azaelectrocyclization as a New Strategy for Alkaloid Synthesis

(2013) Shigeo Katsumura et al.   HETEROCYCLES

Total Synthesis of the Benzo[c]phenanthridine Alkaloids, Terihanine and Isoterihanine, and Their Antitumor Activity

(2013) Tominari Choshi et al.   HETEROCYCLES

Synthesis of Heterocycles via Nucleophilic Substitution of Hydrogen in Nitroarenes

(2013) Mieczysław Mąkosza et al.   HETEROCYCLES

Modular Synthesis of Lamellarins via Regioselective Assembly of 3,4,5-Differentially Arylated Pyrrole-2-carboxylates

(2013) Masashi Komatsubara et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of Lyconadins A–C

(2013) Takuya Nishimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Origins of 1,6-Stereoinduction in Torquoselective 6π Electrocyclizations

(2013) Ashay Patel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unstabilized Azomethine Ylides for the Stereoselective Synthesis of Substituted Piperidines, Tropanes, and Azabicyclo[3.1.0] Systems

(2013) Michael A. Ischay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation

(2013) Katsunori Tanaka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structurally diverse hamigerans from the New Zealand marine sponge Hamigera tarangaensis: NMR-directed isolation, structure elucidation and antifungal activity

(2013) A. Jonathan Singh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Syntheses of 3,4-Benzotropolones by Ring-Closing Metatheses

(2013) Deniz Arican et al.   ORGANIC LETTERS

A New Route to α-Carbolines Based on 6π-Electrocyclization of Indole-3-alkenyl Oximes

(2013) Sophie J. Markey et al.   ORGANIC LETTERS

Pyridone Annulation via Tandem Curtius Rearrangement/6π-Electrocyclization: Total Synthesis of (−)-Lyconadin C

(2013) Xiayun Cheng et al.   ORGANIC LETTERS

Total Synthesis of (−)-Hippodamine by Stereocontrolled Construction of Azaphenalene Skeleton Based on Extended One-Pot Asymmetric Azaelectrocyclization

(2013) Shintaro Fujita et al.   ORGANIC LETTERS

Synthesis of Isoquinuclidines from Highly Substituted Dihydropyridines via the Diels–Alder Reaction

(2013) Rhia M. Martin et al.   ORGANIC LETTERS

Proton Donor Acidity Controls Selectivity in Nonaromatic Nitrogen Heterocycle Synthesis

(2013) S. Duttwyler et al.   SCIENCE

Simple and General Procedure for the Synthesis of α,β-Alkynyl Ketones from Nitriles Using Alkynyldimethylaluminum Reagents

(2013) Sang-Hyeup Lee et al.   SYNLETT

Developments in the Synthesis of 1,2-Dihydropyridines

(2013) Artur Silva et al.   SYNTHESIS-STUTTGART

Recent Advances in the Design, Synthesis, and Biological Evaluation of Selective DYRK1A Inhibitors: A New Avenue for a Disease Modifying Treatment of Alzheimer’s?

(2012) Breland Smith et al.   ACS Chemical Neuroscience

Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition to N-Activated Pyridines

(2012) James A. Bull et al.   CHEMICAL REVIEWS

Bio-imaging and cancer targeting with glycoproteins and N-glycans

(2012) Koichi Fukase et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Organocuprate-Initiated Domino Michael-Intramolecular Aldol Reaction - Application to the Formation of Ring B of the Aglycon of Landomycins

(2012) Xavier Bugaut et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

First Total Syntheses of 1,3-Disubstituted β-Carboline Alkaloids, Dichotomide I and Marinacarbolines A-D

(2012) Satoshi Hibino et al.   HETEROCYCLES

Application of the Multi-standard Methodology for Calculating 1H NMR Chemical Shifts

(2012) Ariel M. Sarotti et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereocontrolled Synthesis of Substituted Chiral Piperidines viaOne-Pot Asymmetric 6π-Azaelectrocyclization: Asymmetric Syntheses of(−)-Dendroprimine, (+)-7-Epidendroprimine, (+)-5-Epidendroprimine, and (+)-5,7-Epidendroprimine

(2012) Toyoharu Kobayashi et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Diastereoselective Synthesis of Tetrahydropyridines by a C–H Activation–Cyclization–Reduction Cascade

(2012) Simon Duttwyler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of the unique angular tricyclic chromone structure proposed for aspergillitine, and its relationship with alkaloid TMC-120B

(2012) Sebastián O. Simonetti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Divergent Stereocontrol of Acid Catalyzed Intramolecular Aldol Reactions of 2,3,7-Triketoesters: Synthesis of Highly Functionalized Cyclopentanones

(2012) Phong Truong et al.   ORGANIC LETTERS

Palladium-Catalyzed Asymmetric 6-Endo Cyclization of Dienamides with Substituent-Driven Activation

(2012) Hiroshi Tsuchikawa et al.   ORGANIC LETTERS

Electrocyclization of Oxatrienes in the Construction of Structurally Complex Pyranopyridones

(2012) Anna D. Fotiadou et al.   ORGANIC LETTERS

A Torquoselective 6π Electrocyclization Approach to Reserpine Alkaloids

(2012) Gregg A. Barcan et al.   ORGANIC LETTERS

TBAHS-Catalyzed Synthesis of 2-Dihydroquinazolin-2-ylquinoline: An Efficient and Practical Synthesis of Naturally Occurring Alkaloids Luotonin A, B, and E

(2012) Lingaiah Nagarapu et al.   SYNLETT

A novel total synthesis of isocryptolepine based on a microwave-assisted tandem Curtius rearrangement and aza-electrocyclic reaction

(2012) Kaori Hayashi et al.   TETRAHEDRON

Recent advances in new multicomponent synthesis of structurally diversified 1,4-dihydropyridines

(2012) Jie-Ping Wan et al.   RSC Advances

Cell surface biotinylation by azaelectrocyclization: Easy-handling and versatile approach for living cell labeling

(2011) Katsunori Tanaka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Asymmetric electrocyclic reactions

(2011) Sam Thompson et al.   CHEMICAL SOCIETY REVIEWS

Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages

(2011) Thomas. G. Rand et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies

(2011) Douglas C. Behenna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lewis Base Catalyzed [4+2] Annulation of Electron-Deficient Chromone-Derived Heterodienes and Acetylenes

(2011) Heiko Dückert et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthetic Studies on Nitrogen-Containing Fused-Heterocyclic Compounds Based on Thermal Electrocyclic Reactions of 6π-Electron and Aza 6π-Electron Systems

(2011) Satoshi Hibino et al.   HETEROCYCLES

Improved Synthesis of the New Furo[3,2-h]isoquinoline Alkaloids TMC-120B and TMC-120A, and Their Inhibitory Activities against IFN-γ and IL-4 Production

(2011) Satoshi Hibino et al.   HETEROCYCLES

A One-Pot Synthesis and Biological Activity of Ageladine A and Analogues

(2011) Sudhir R. Shengule et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimalarial β-Carboline and Indolactam Alkaloids from Marinactinospora thermotolerans, a Deep Sea Isolate

(2011) Hongbo Huang et al.   JOURNAL OF NATURAL PRODUCTS

Substituent Effects on the Iodine-Catalyzed Thermal Cyclization of 3,4-Diphenylbuta-1,3-dienyl Isocyanates: Mechanistic Studies

(2011) Ta-Hsien Chuang et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Absolute Stereochemical Assignment of Kibdelone C

(2011) David L. Sloman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Studies on Luotonins

(2011) Jing Lu Liang et al.   MOLECULES

Natural product–inspired cascade synthesis yields modulators of centrosome integrity

(2011) Heiko Dückert et al.   Nature Chemical Biology

Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams

(2011) Douglas C. Behenna et al.   Nature Chemistry

Target-selective fluorescent “switch-on” protein labeling by 6π-azaelectrocyclization

(2011) Katsunori Tanaka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

[1,5]-H Shift of Aldehyde Hydrogen in Dienal Compounds to Produce Ketenes

(2011) Taku Sakaguchi et al.   ORGANIC LETTERS

One-Pot Synthesis of Luotonin A and Its Analogues

(2011) Ming-Chung Tseng et al.   ORGANIC LETTERS

Discovery and application of 6π-azaelectrocyclization to natural product synthesis and synthetic biology

(2011) Katsunori Tanaka et al.   Science China-Chemistry

Exploring a Unique Reactivity of 6π-Azaelectrocyclization to Enzyme Inhibition, Natural Products Synthesis, and Molecular Imaging: An Approach to Chemical Biology by Synthetic Chemists

(2011) Katsunori Tanaka et al.   SYNLETT

Synthesis and cyclizations of 1-azapolyene derivatives

(2011) Zoltán Vincze et al.   TETRAHEDRON

Palladium-catalyzed asymmetric alkylation in the synthesis of cyclopentanoid and cycloheptanoid core structures bearing all-carbon quaternary stereocenters

(2011) Allen Y. Hong et al.   TETRAHEDRON

An efficient new route towards biologically active isocryptolepine and γ-carboline derivatives using an intramolecular thermal electrocyclization strategy

(2011) Dattatray G. Hingane et al.   TETRAHEDRON LETTERS

Toward new camptothecins. Part 7: Synthesis of thioluotonin and its 5-methoxycarbonyl derivative

(2011) Thomas Boisse et al.   TETRAHEDRON LETTERS

New type of azacyclization: thermal preparation of 4,6-disubstituted 2-piperidinone from N-sulfonyldienamide and its substituent effect

(2011) Yuya Maekawa et al.   TETRAHEDRON LETTERS

Progress on lamellarins

(2011) Daniel Pla et al.   MedChemComm

Solvent-free reductive amination of aromatic aldehydes catalyzed by CeCl3·7H2O

(2011) Rohit Lokhande et al.   Green Chemistry Letters and Reviews

Total Synthesis of Jadomycin A and a Carbasugar Analogue of Jadomycin B

(2010) Mingde Shan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D

(2010) Caroline Ballot et al.   APOPTOSIS

Synthesis and Biological Properties of Luotonin A Derivatives

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Enantioselective 6 π Electrocyclizations: Pushing the Limits in Organocatalytic Pericyclic Reactions

(2010) Jose L. Vicario et al.   ChemCatChem

A novel chiral oxazolidine organocatalyst for the synthesis of an oseltamivir intermediate using a highly enantioselective Diels–Alder reaction of 1,2-dihydropyridine

(2010) Hiroto Nakano et al.   CHEMICAL COMMUNICATIONS

New strategy in synthetic biology: from enzyme inhibition and natural products synthesis to PET imaging by 6π-azaelectrocyclization

(2010) Katsunori Tanaka et al.   CHEMICAL RECORD

Electrocyclization-Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking

(2010) Katsunori Tanaka et al.   ChemMedChem

Activation, regulation, and inhibition of DYRK1A

(2010) Walter Becker et al.   FEBS Journal

The role of DYRK1A in neurodegenerative diseases

(2010) Jerzy Wegiel et al.   FEBS Journal

Total Synthesis of Bioactive Indolo[3,2-j]phenanthridine Alkaloid, Calothrixin B

(2010) Satoshi Hibino et al.   HETEROCYCLES

Limonoids from the Seeds of a Hainan Mangrove,Xylocarpus granatum

(2010) Jian-Yu Pan et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of (+)-Fastigiatine

(2010) Brian B. Liau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of the Lycopodium Alkaloid (+)-Lycoflexine

(2010) Jürgen Ramharter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Situ Generated Bulky Palladium Hydride Complexes as Catalysts for the Efficient Isomerization of Olefins. Selective Transformation of Terminal Alkenes to 2-Alkenes

(2010) Delphine Gauthier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry of the cortistatins–a novel class of anti-angiogenic agents

(2010) David Yu-Kai Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Total synthesis of (−)-20-epiuleinevia stereocontrolled one-pot asymmetric azaelectrocyclization followed by novel 1,4-addition reaction

(2010) Taku Sakaguchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis

(2010) Krista M. Cottreau et al.   ORGANIC LETTERS

Copper-Promoted Carbon-Heteroatom Bond Cross-Coupling with Boronic Acids and Derivatives

(2010) Jennifer Qiao et al.   SYNTHESIS-STUTTGART

An efficient synthesis of chiral isoquinuclidines by Diels–Alder reaction using Lewis acid catalyst

(2010) Masafumi Hirama et al.   TETRAHEDRON

Total synthesis of benzo[c]phenanthridine alkaloids based on a microwave-assisted electrocyclic reaction of the aza 6π-electron system and structural revision of broussonpapyrine

(2010) Yuhsuke Ishihara et al.   TETRAHEDRON

Lyconadins C and F, new Lycopodium alkaloids from Lycopodium complanatum

(2010) Kan’ichiro Ishiuchi et al.   TETRAHEDRON LETTERS

Synthesis and structure–activity relationships of cassiarin A as potential antimalarials with vasorelaxant activity

(2009) Hiroshi Morita et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors

(2009) Anh P. Truong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Efficient synthesis of 2,4,5-trisubstituted 2,5-chiral tetrahydropyridines using a one-pot asymmetric azaelectrocyclization protocol

(2009) Toyoharu Kobayashi et al.   CHEMICAL COMMUNICATIONS

Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment

(2009) J.D. Miller et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Library-directed Solution- and Solid-phase Synthesis of 2,4-Disubstituted Pyridines: One-pot Approach through 6 π-Azaelectrocyclization

(2009) Taku Sakaguchi et al.   Chemistry-An Asian Journal

Electrocyclization-Mediated Approach to 2-Methyltriclisine, an Unnatural Analog of the Azafluoranthene Alkaloid Triclisine

(2009) Claudio C. Silveira et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Antiplasmodial Activity of Aminoalkylamino-Substituted Neocryptolepine Derivatives

(2009) Ibrahim El Sayed et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cassiarins C−E, Antiplasmodial Alkaloids from the Flowers ofCassia siamea

(2009) Shiori Oshimi et al.   JOURNAL OF NATURAL PRODUCTS

Cyclocondensation of α-Aminonitriles and Enones: A Short Access to 3,4-Dihydro-2H-pyrrole 2-carbonitriles and 2,3,5-Trisubstituted Pyrroles

(2009) Ines Bergner et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-Promoted Syntheses of Quinazolines and Dihydroquinazolines from 2-AminoarylalkanoneO-Phenyl Oximes

(2009) Fernando Portela-Cubillo et al.   JOURNAL OF ORGANIC CHEMISTRY

Operationally Simple Copper-Promoted Coupling of Terminal Alkynes with Benzyl Halides

(2009) Katherine A. Davies et al.   JOURNAL OF ORGANIC CHEMISTRY

Concise Total Syntheses of theLycopodiumAlkaloids (±)-Nankakurines A and B via Luciduline

(2009) Xiayun Cheng et al.   ORGANIC LETTERS

Aaptamine and related products. Their isolation, chemical syntheses, and biological activity

(2009) Enrique L. Larghi et al.   TETRAHEDRON

Synthesis of indole alkaloid (−)-corynantheidol and formal synthesis of (−)-corynantheidine via one-pot asymmetric azaelectrocyclization

(2009) Yanwu Li et al.   TETRAHEDRON LETTERS

Synthesis of 3,4-Dihydroisoquinolines by a C(sp3)H Activation/Electrocyclization Strategy: Total Synthesis of Coralydine

(2008) Manon Chaumontet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Aminoallylation of Aldehydes: A Catalytic Enantioselective Aza-Cope Rearrangement

(2008) Magnus Rueping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Natural Product Inspired Tricyclic Benzopyrones by an Organocatalyzed Annulation Reaction

(2008) Herbert Waldmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Enantioselective Total Synthesis of a β-Carboline Alkaloid, (S)-(−)-Dichotomine C

(2008) Kana Omura et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis of Indolobenzazepinones by Application of an Isocyanide-Based Multicomponent Reaction

(2008) Stéphane Beaumont et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Biomimetic Total Syntheses of Cassiarins A and B

(2008) Yuan-Shan Yao et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Formal Synthesis of (+)-Dihydrocorynantheine and (−)-Dihydrocorynantheol†

(2008) Mercedes Amat et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Claisen Rearrangements with a Hydrogen-Bond Donor Catalyst

(2008) Christopher Uyeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formal Synthesis of (−)-Kendomycin Featuring a Prins-Cyclization To Construct the Macrocycle

(2008) Kevin B. Bahnck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Synthesis of Lycopodine

(2008) Hua Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Simple, Modular Synthesis of Substituted Pyridines

(2008) Songbai Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Benzocyclobutenes by Palladium-Catalyzed C−H Activation of Methyl Groups: Method and Mechanistic Study

(2008) Manon Chaumontet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Eugenol and its synthetic analogues inhibit cell growth of human cancer cells (Part I)

(2008) H. Carrasco A. et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Structure elucidation of an unprecedented alkaloid and a new limonoid fromXylocarpus granatum

(2008) Jianxin Cui et al.   MAGNETIC RESONANCE IN CHEMISTRY

Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

(2008) Dianne Baunbæk et al.   Marine Drugs

Recent Advances in Positron Emission Tomography (PET) Imaging of Biomolecules: From Chemical Labeling to Cancer Diagnostics

(2008) Katsunori Tanaka et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Biomimetic synthesis of the IDO inhibitors exiguamine A and B

(2008) Matthew Volgraf et al.   Nature Chemical Biology

PET (positron emission tomography) imaging of biomolecules using metal–DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics

(2008) Katsunori Tanaka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A formal total synthesis of the marine alkaloid aaptamine

(2008) Enrique L. Larghi et al.   TETRAHEDRON

Novel synthesis of the 2-azaanthraquinone alkaloid, scorpinone, based on two microwave-assisted pericyclic reactions

(2008) Tominari Choshi et al.   TETRAHEDRON LETTERS

An efficient method for construction of tetrahydroisoquinoline skeleton via double cyclization process using ortho-vinylbenzaldehydes and amino alcohols: application to the synthesis of (S)-cryptostyline II

(2008) Kazuteru Umetsu et al.   TETRAHEDRON LETTERS

A novel strategy for the synthesis of 2-arylpyridines using one-pot 6π-azaelectrocyclization

(2008) Toyoharu Kobayashi et al.   TETRAHEDRON LETTERS

A new synthesis of the benzo[c]phenanthridines nornitidine, noravicine, and isodecarine, based on a microwave-assisted electrocyclic reaction of the aza 6π-electron system

(2008) Kakujiro Kohno et al.   TETRAHEDRON LETTERS

A Submicrogram-Scale Protocol for Biomolecule-Based PET Imaging by Rapid 6π-Azaelectrocyclization: Visualization of Sialic Acid Dependent Circulatory Residence of Glycoproteins

(2007) Katsunori Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms

(2007) Hui Fan et al.   CHEMICAL REVIEWS

Xylogranatins F–R: Antifeedants from the Chinese Mangrove,Xylocarpus granatum, A New Biogenetic Pathway to Tetranortriterpenoids

(2007) Jun Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL