Another Facet to the Anticancer Response to Lamellarin D: Induction of Cellular Senescence through Inhibition of Topoisomerase I and Intracellular Ros Production

Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells

(2013) HONGMEI LUO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Recent Advances in the Discovery and Development of Marine Microbial Natural Products

(2013) Zhi-Qiang Xiong et al.   Marine Drugs

Inactivation of the HIF-1 /PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants

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Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

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DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

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Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II

(2011) Caroline Ballot et al.   APOPTOSIS

Clinical and pharmacokinetic evaluation of trabectedin for the treatment of soft-tissue sarcoma

(2011) Angela Cioffi et al.   Expert Opinion on Drug Metabolism & Toxicology

Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species

(2011) Santhi Achuthan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D

(2010) Caroline Ballot et al.   APOPTOSIS

Therapy-Induced Senescence in Cancer

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The Use of Positron Emission Tomography in Soft Tissue Sarcoma Patients under Therapy with Trabectedin

(2009) Bernd Kasper et al.   Marine Drugs

Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D

(2009) C. Ballot et al.   MOLECULAR CANCER THERAPEUTICS

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Accelerated senescence: An emerging role in tumor cell response to chemotherapy and radiation

(2008) David A. Gewirtz et al.   BIOCHEMICAL PHARMACOLOGY

Apoptosis-related mitochondrial dysfunction defines human monocyte-derived dendritic cells with impaired immuno-stimulatory capacities

(2008) Laurent Castera et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

(2008) Dianne Baunbæk et al.   Marine Drugs

NOX enzymes as novel targets for drug development

(2008) J. David Lambeth et al.   Seminars in Immunopathology