Overlapped Metabolic and Therapeutic Links between Alzheimer and Diabetes
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Overlapped Metabolic and Therapeutic Links between Alzheimer and Diabetes
Authors
Keywords
Alzheimers disease, Diabetes, Pathophysiology, Impaired metabolism, Therapies, <em class=EmphasisTypeItalic >C. elegans</em>
Journal
MOLECULAR NEUROBIOLOGY
Volume 47, Issue 1, Pages 399-424
Publisher
Springer Nature
Online
2012-09-26
DOI
10.1007/s12035-012-8352-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Model Caenorhabditis elegans in Diabetes Mellitus and Alzheimer's Disease
- (2017) Michael Morcos et al. JOURNAL OF ALZHEIMERS DISEASE
- RAGE and Alzheimer's Disease: A Progression Factor for Amyloid-β-Induced Cellular Perturbation?
- (2017) Shi Du Yan et al. JOURNAL OF ALZHEIMERS DISEASE
- An Integrative View of the Role of Oxidative Stress, Mitochondria and Insulin in Alzheimer's Disease
- (2017) Paula I. Moreira et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid-β as a Modulator of Synaptic Plasticity
- (2017) Mordhwaj S. Parihar et al. JOURNAL OF ALZHEIMERS DISEASE
- Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment
- (2017) Mark A. Smith et al. JOURNAL OF ALZHEIMERS DISEASE
- Role of By-Products of Lipid Oxidation in Alzheimer's Disease Brain: A Focus on Acrolein
- (2017) Manjeet Singh et al. JOURNAL OF ALZHEIMERS DISEASE
- Respiratory complications of obesity
- (2013) S. Mandal et al. CLINICAL MEDICINE
- Tissue cholesterol content alterations in streptozotocin-induced diabetic rats
- (2012) Xin-ting Wang et al. ACTA PHARMACOLOGICA SINICA
- Cognitive decline in STZ-3V rats is largely due to dysfunctional insulin signalling through the dentate gyrus
- (2012) Akiko Sheala Shingo et al. BEHAVIOURAL BRAIN RESEARCH
- Cell oxidant stress delivery and cell dysfunction onset in type 2 diabetes
- (2012) Asma Kassab et al. BIOCHIMIE
- Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation
- (2012) Sónia C. Correia et al. BRAIN RESEARCH
- Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease
- (2012) Rajesh Chaudhary et al. Cardiovascular Diabetology
- Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE−/− mice
- (2012) Gillian Douglas et al. CARDIOVASCULAR RESEARCH
- Mechanisms for Insulin Resistance: Common Threads and Missing Links
- (2012) Varman T. Samuel et al. CELL
- Minireview: Epigenetics of Obesity and Diabetes in Humans
- (2012) Howard Slomko et al. ENDOCRINOLOGY
- Signaling Mechanisms in the Regulation of Renal Matrix Metabolism in Diabetes
- (2012) Meenalakshmi M. Mariappan Experimental Diabetes Research
- Activation of ERK1/2-CREB pathway during potentiating synaptic transmission of ( − )clausenamide in rat dentate gyrus
- (2012) Jin-Feng Hu et al. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
- Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways
- (2012) Wen Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
- (2012) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Nucleobindin 1 Caps Human Islet Amyloid Polypeptide Protofibrils to Prevent Amyloid Fibril Formation
- (2012) Ruchi Gupta et al. JOURNAL OF MOLECULAR BIOLOGY
- Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
- (2012) Scott A Yuzwa et al. Nature Chemical Biology
- Nitric Oxide-Mediated Oxidative Damage and the Progressive Demise of Motor Neurons in ALS
- (2012) Derek A. Drechsel et al. NEUROTOXICITY RESEARCH
- Non-coding RNAs—Novel targets in neurotoxicity
- (2012) Tamara L. Tal et al. NEUROTOXICOLOGY
- Can Alzheimer Disease Be a Form of Type 3 Diabetes?
- (2012) Giulia Accardi et al. REJUVENATION RESEARCH
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Changes in cognitive function in patients with diabetes mellitus
- (2012) Barbara Szémán et al. ORVOSI HETILAP
- Potential Role of Acrolein in Neurodegeneration and in Alzheimers Disease
- (2012) Dang Thanh Nam et al. Current Molecular Pharmacology
- Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?
- (2011) Sónia C. Correia et al. AGEING RESEARCH REVIEWS
- Risk factors of dementia in North India: a case–control study
- (2011) Manjari Tripathi et al. AGING & MENTAL HEALTH
- Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy
- (2011) Juha J. Hulmi et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications
- (2011) Ravichandran Ramasamy et al. Annals of the New York Academy of Sciences
- Redox Proteomics in Selected Neurodegenerative Disorders: From Its Infancy to Future Applications
- (2011) D. Allan Butterfield et al. ANTIOXIDANTS & REDOX SIGNALING
- The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update
- (2011) Hanrui Zhang et al. BASIC RESEARCH IN CARDIOLOGY
- Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells
- (2011) João Agostinho Machado-Neto et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Circulating biomarkers of protein oxidation for Alzheimer disease: Expectations within limits
- (2011) Fabio Di Domenico et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Lipid Metabolism and Glial Lipoproteins in the Central Nervous System
- (2011) Hideki Hayashi BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions
- (2011) Julijana Milojevic et al. BIOPHYSICAL JOURNAL
- Mitochondrial membrane potential probes and the proton gradient: a practical usage guide
- (2011) Seth W. Perry et al. BIOTECHNIQUES
- Insulin Receptors and Downstream Substrates Associate with Membrane Microdomains after Treatment with Insulin or Chromium(III) Picolinate
- (2011) Abeer Al-Qatati et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways
- (2011) Jose R. Bayascas CELL CYCLE
- Insulin Resistance, Hyperglycemia, and Atherosclerosis
- (2011) Karin E. Bornfeldt et al. Cell Metabolism
- Misfolded proteins in Alzheimer's disease and type II diabetes
- (2011) Alaina S. DeToma et al. CHEMICAL SOCIETY REVIEWS
- Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease
- (2011) Anton Rahmadi et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Age- and gender-related alteration in plasma advanced oxidation protein products (AOPP) and glycosaminoglycan (GAG) concentrations in physiological ageing
- (2011) Katarzyna Komosinska-Vassev et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Role of Advanced Glycation End Products (AGEs) in Osteoporosis in Diabetes
- (2011) Sho-ichi Yamagishi CURRENT DRUG TARGETS
- Antioxidant Pathways in Alzheimers Disease: Possibilities of Intervention
- (2011) J. Vina et al. CURRENT PHARMACEUTICAL DESIGN
- Type 2 Diabetes and Late-Onset Alzheimer’s Disease
- (2011) D. Cheng et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Beyond the Hormone: Insulin as an Autoimmune Target in Type 1 Diabetes
- (2011) Vedran Brezar et al. ENDOCRINE REVIEWS
- Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells
- (2011) Li-min Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Aβ proteotoxicity in Caenorhabditis elegans
- (2011) Kopal Saharia et al. EXPERIMENTAL GERONTOLOGY
- Impaired Mitochondrial Respiratory Functions and Oxidative Stress in Streptozotocin-Induced Diabetic Rats
- (2011) Haider Raza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Receptor for Advanced Glycation End Products (RAGE) Prevents Endothelial Cell Membrane Resealing and Regulates F-actin Remodeling in a β-Catenin-dependent Manner
- (2011) Fei Xiong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes
- (2011) Shi-Xiong Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis
- (2011) Domenico Bosco et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Neurovascular function in Alzheimer's disease patients and experimental models
- (2011) Nektaria Nicolakakis et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A Common Pathogenic Mechanism Linking Type-2 Diabetes and Alzheimer's Disease: Evidence from Animal Models
- (2011) Sun Ah Park Journal of Clinical Neurology
- Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
- (2011) Ying Liu et al. JOURNAL OF PATHOLOGY
- Diabetes-Induced Central Cholinergic Neuronal Loss and Cognitive Deficit Are Attenuated by Tacrine and a Chinese Herbal Prescription, Kangen-Karyu: Elucidation in Type 2 Diabetes db/db Mice
- (2011) Qi Zhao et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Cell signaling and receptors in toxicity of advanced glycation end products (AGEs): α-dicarbonyls, radicals, oxidative stress and antioxidants
- (2011) Peter Kovacic et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Insulin Resistance: the Link Between Obesity and Cardiovascular Disease
- (2011) Gerald M. Reaven MEDICAL CLINICS OF NORTH AMERICA
- Dietary lipids and their oxidized products in Alzheimer's disease
- (2011) Laura Corsinovi et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Effects of amyloid-β peptides on voltage-gated L-type CaV1.2 and CaV1.3 Ca2+ channels
- (2011) Sunoh Kim et al. MOLECULES AND CELLS
- Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport
- (2011) Kazuaki Ohtsubo et al. NATURE MEDICINE
- Linking lipids to Alzheimer's disease: cholesterol and beyond
- (2011) Gilbert Di Paolo et al. NATURE REVIEWS NEUROSCIENCE
- Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer’s disease
- (2011) Rupinder K. Sodhi et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer’s-like changes
- (2011) Amit Gupta et al. NEUROPHARMACOLOGY
- Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
- (2011) K. J. Anstey et al. Obesity Reviews
- Caloric restriction and chronic inflammatory diseases
- (2011) OA González et al. ORAL DISEASES
- Hydroxyl Radical and Its Scavengers in Health and Disease
- (2011) Boguslaw Lipinski Oxidative Medicine and Cellular Longevity
- Involvement of 5-Lipoxygenase in the Corticosteroid-Dependent Amyloid Beta Formation: In Vitro and In Vivo Evidence
- (2011) Simone Puccio et al. PLoS One
- Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle
- (2011) Silvie Timmers et al. PLoS One
- Hydrogen Peroxide Probes Directed to Different Cellular Compartments
- (2011) Mikalai Malinouski et al. PLoS One
- Inhibition of the Mitochondrial Enzyme ABAD Restores the Amyloid-β-Mediated Deregulation of Estradiol
- (2011) Yun-An Lim et al. PLoS One
- Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt
- (2011) J.-i. Sakamaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The potential role of epigenetic responses to diet in ageing
- (2011) Dianne Ford et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- The future of Alzheimer's disease: The next 10 years
- (2011) Harald Hampel et al. PROGRESS IN NEUROBIOLOGY
- Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction
- (2011) Shreaya Chakroborty et al. Science China-Life Sciences
- Advances in metal-induced oxidative stress and human disease
- (2011) Klaudia Jomova et al. TOXICOLOGY
- Reactive Oxygen Species Production by Forward and Reverse Electron Fluxes in the Mitochondrial Respiratory Chain
- (2011) Vitaly A. Selivanov et al. PLoS Computational Biology
- Promiscuous affairs of PKB/AKT isoforms in metabolism
- (2011) Simon M. Schultze et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies
- (2011) Miguel Medina et al. Frontiers in Molecular Neuroscience
- GSK-3: Functional Insights from Cell Biology and Animal Models
- (2011) Oksana Kaidanovich-Beilin et al. Frontiers in Molecular Neuroscience
- Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes
- (2010) Laura D. Baker et al. ARCHIVES OF NEUROLOGY
- Links between ApoE, brain cholesterol metabolism, tau and amyloid β-peptide in patients with cognitive impairment
- (2010) Valerio Leoni et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- ACAT inhibition and amyloid beta reduction
- (2010) Raja Bhattacharyya et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration
- (2010) Radosveta Koldamova et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Membrane rafts in Alzheimer's disease beta-amyloid production
- (2010) Kulandaivelu S. Vetrivel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease☆
- (2010) D. Allan Butterfield et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Modeling human diseases in Caenorhabditis elegans
- (2010) Maria Markaki et al. Biotechnology Journal
- Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?
- (2010) Kawser Akter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Maillard reaction of ribose 5-phosphate generates superoxide and glycation products for bovine heart cytochrome c reduction
- (2010) Rebecca A. Gersten et al. CARBOHYDRATE RESEARCH
- Oxidative Stress and Diabetic Complications
- (2010) Ferdinando Giacco et al. CIRCULATION RESEARCH
- The sites and topology of mitochondrial superoxide production
- (2010) Martin D. Brand EXPERIMENTAL GERONTOLOGY
- Oxysterols: A world to explore
- (2010) A. Otaegui-Arrazola et al. FOOD AND CHEMICAL TOXICOLOGY
- Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease
- (2010) M.A. Bradley et al. FREE RADICAL BIOLOGY AND MEDICINE
- Identification of the oxidative stress proteome in the brain
- (2010) Rukhsana Sultana et al. FREE RADICAL BIOLOGY AND MEDICINE
- Advances in methods for the determination of biologically relevant lipid peroxidation products
- (2010) Corinne M. Spickett et al. FREE RADICAL RESEARCH
- How does diabetes accelerate Alzheimer disease pathology?
- (2010) Catrina Sims-Robinson et al. Nature Reviews Neurology
- Inability of Plasma and Urine F2A-Isoprostane Levels to Differentiate Mild Cognitive Impairment from Alzheimer’s Disease
- (2010) Elliott J. Mufson et al. Neurodegenerative Diseases
- Oxidative stress in Alzheimer disease: A possibility for prevention
- (2010) David J. Bonda et al. NEUROPHARMACOLOGY
- Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation
- (2010) Franco Folli et al. PLoS One
- Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
- (2010) Brian Onken et al. PLoS One
- Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease
- (2010) Martín Gómez Ravetti et al. PLoS One
- Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
- (2010) E. Kickstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A deposition in an Alzheimer mouse model with diabetes
- (2010) S. Takeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic regulation in the pathophysiology of Alzheimer's disease
- (2010) Leonidas Chouliaras et al. PROGRESS IN NEUROBIOLOGY
- Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters
- (2010) Susana Cardoso et al. SYNAPSE
- Retinoid X receptors: common heterodimerization partners with distinct functions
- (2010) Philippe Lefebvre et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Insulin signaling meets mitochondria in metabolism
- (2010) Zhiyong Cheng et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- PTEN in liver diseases and cancer
- (2010) Marion Peyrou WORLD JOURNAL OF GASTROENTEROLOGY
- The role of insulin signaling in the development of β-cell dysfunction and diabetes
- (2010) Qinghua Wang et al. Islets
- Assaying β-amyloid Toxicity using a Transgenic C. elegans Model
- (2010) Vishantie Dostal et al. Jove-Journal of Visualized Experiments
- RNA oxidation in Alzheimer disease and related neurodegenerative disorders
- (2009) Akihiko Nunomura et al. ACTA NEUROPATHOLOGICA
- Dysregulation of Insulin Signaling, Glucose Transporters, O -GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain
- (2009) Yanqiu Deng et al. AMERICAN JOURNAL OF PATHOLOGY
- Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
- (2009) Richard Killick et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ternary Complexes of Iron, Amyloid-β, and Nitrilotriacetic Acid: Binding Affinities, Redox Properties, and Relevance to Iron-Induced Oxidative Stress in Alzheimer’s Disease
- (2009) Dianlu Jiang et al. BIOCHEMISTRY
- The essential role of lipids in Alzheimer's disease
- (2009) Sabrina Florent-Béchard et al. BIOCHIMIE
- Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
- (2009) F. Liu et al. BRAIN
- Abnormal calcium homeostasis in peripheral neuropathies
- (2009) Paul Fernyhough et al. CELL CALCIUM
- Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease
- (2009) Sarah Aldred et al. CLINICAL BIOCHEMISTRY
- Effects of Caloric Restriction on Cardiovascular Aging in Non-human Primates and Humans
- (2009) Christina Cruzen et al. CLINICS IN GERIATRIC MEDICINE
- Cholesterol Oxidation Products and Disease: An Emerging Topic of Interest in Medicinal Chemistry
- (2009) Barbara Sottero et al. CURRENT MEDICINAL CHEMISTRY
- Reactive species and diabetes: counteracting oxidative stress to improve health
- (2009) Patricia Pérez-Matute et al. CURRENT OPINION IN PHARMACOLOGY
- Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes
- (2009) Charlotte Ling et al. DIABETES
- Depression and Advanced Complications of Diabetes: A prospective cohort study
- (2009) E. H.B. Lin et al. DIABETES CARE
- Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
- (2009) S. Zraika et al. DIABETOLOGIA
- Metabolic links between diabetes and Alzheimer’s disease
- (2009) Pamela A Maher et al. Expert Review of Neurotherapeutics
- Neuronal IGF-1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer’s disease
- (2009) Susanna Freude et al. FASEB JOURNAL
- Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells
- (2009) Shankar Munusamy et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
- (2009) H. Chen et al. HUMAN MOLECULAR GENETICS
- Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study
- (2009) J M Jakicic et al. INTERNATIONAL JOURNAL OF OBESITY
- Transglutaminases and neurodegeneration
- (2009) Thomas M. Jeitner et al. JOURNAL OF NEUROCHEMISTRY
- Brain glucose transporters,O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease
- (2009) Ying Liu et al. JOURNAL OF NEUROCHEMISTRY
- PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS
- (2009) Haruo Hanyu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Paraoxonase activity and dementia
- (2009) Hanna Wehr et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Endurance exercise causes mitochondrial and oxidative stress in rat liver: Effects of a combination of mitochondrial targeting nutrients
- (2009) Lijuan Sun et al. LIFE SCIENCES
- Targeting protein kinases in central nervous system disorders
- (2009) Laura K. Chico et al. NATURE REVIEWS DRUG DISCOVERY
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
- (2009) Velandai Srikanth et al. NEUROBIOLOGY OF AGING
- Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
- (2009) Tomohiko Sato et al. NEUROBIOLOGY OF AGING
- Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
- (2009) Lenka Munoz et al. NEUROPHARMACOLOGY
- RAGE-mediated signaling contributes to intraneuronal transport of amyloid- and neuronal dysfunction
- (2009) K. Takuma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
- (2009) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
- (2009) R. J. Colman et al. SCIENCE
- Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway
- (2008) Yasuki Higaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Prevention and promotion effects of apolipoprotein E4 on amylin aggregation
- (2008) Peng Lei et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
- (2008) Wei-Qin Zhao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic β-cell
- (2008) A WIEDERKEHR et al. CELL CALCIUM
- Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes
- (2008) A VERKHRATSKY et al. CELL CALCIUM
- Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats: A Role for Glycogen Synthase Kinase-3
- (2008) M. Collino et al. DIABETES
- mTOR Inhibition by Rapamycin Prevents -Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes
- (2008) M. Fraenkel et al. DIABETES
- Islet Amyloid in Type 2 Diabetes, and the Toxic Oligomer Hypothesis
- (2008) Leena Haataja et al. ENDOCRINE REVIEWS
- Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease
- (2008) José Alejandro Luchsinger EUROPEAN JOURNAL OF PHARMACOLOGY
- Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
- (2008) Ying Liu et al. FEBS LETTERS
- Nucleic acid oxidation in Alzheimer disease
- (2008) Paula I. Moreira et al. FREE RADICAL BIOLOGY AND MEDICINE
- FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice
- (2008) Jon Valla et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation
- (2008) Claus Schneider et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Advanced Glycation End Products in Progression and Complications of Diabetes
- (2008) Su-Yen Goh et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Insulin-like Growth Factor System Regulates Oligodendroglial Cell Behavior: Therapeutic Potential in CNS
- (2008) Daniel Chesik et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits
- (2008) H. Belinson et al. JOURNAL OF NEUROSCIENCE
- Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin
- (2008) C.G. Jolivalt et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
- (2008) Rene O Sanchez-Mejia et al. NATURE NEUROSCIENCE
- ApoE Promotes the Proteolytic Degradation of Aβ
- (2008) Qingguang Jiang et al. NEURON
- Mitochondria in Neuroplasticity and Neurological Disorders
- (2008) Mark P. Mattson et al. NEURON
- Regulation of brain polyunsaturated fatty acid uptake and turnover
- (2008) Chuck T. Chen et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- 5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer’s disease
- (2007) Omidreza Firuzi et al. FASEB JOURNAL
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
- Oxidatively modified RNA in mild cognitive impairment
- (2007) Mark A. Lovell et al. NEUROBIOLOGY OF DISEASE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More