Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
Published 2012 View Full Article
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Title
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
Authors
Keywords
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Journal
Nature Chemical Biology
Volume 8, Issue 4, Pages 393-399
Publisher
Springer Nature
Online
2012-02-27
DOI
10.1038/nchembio.797
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- The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability
- (2009) S. R. Hanson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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