Inhibition of the Mitochondrial Enzyme ABAD Restores the Amyloid-β-Mediated Deregulation of Estradiol

Mitochondrial β-amyloid in Alzheimer's disease: Figure 1

(2011) Eva Borger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modes of Aβ toxicity in Alzheimer’s disease

(2011) Jürgen Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease

(2011) Ji-Seon Seo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intraneuronal APP, Not Free A  Peptides in 3xTg-AD Mice: Implications for Tau versus A -Mediated Alzheimer Neurodegeneration

(2011) M. J. Winton et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Amyloid-  (A ) Peptide-Binding Alcohol Dehydrogenase-A  Interaction Reduces A  Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease

(2011) J. Yao et al.   JOURNAL OF NEUROSCIENCE

Signaling of Reactive Oxygen and Nitrogen Species in Diabetes Mellitus

(2011) Igor Afanas'ev   Oxidative Medicine and Cellular Longevity

An update on the toxicity of Aβ in Alzheimer’s disease

(2011) Jurgen Gotz   Neuropsychiatric Disease and Treatment

Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

(2011) Anne Eckert et al.   Alzheimers Research & Therapy

(−)-CHANA, a Fluorogenic Probe for Detecting Amyloid Binding Alcohol Dehydrogenase HSD10 Activity in Living Cells

(2010) Kirsty E. A. Muirhead et al.   ACS Chemical Biology

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

(2010) Katharina Rauschenberger et al.   EMBO Molecular Medicine

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

(2010) Mary-Elizabeth Patti et al.   ENDOCRINE REVIEWS

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Aβ and human amylin share a common toxicity pathwayviamitochondrial dysfunction

(2010) Yun-An Lim et al.   PROTEOMICS

Common features between diabetes mellitus and Alzheimer’s disease

(2009) J. Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

tRNA recognition, processing, and disease: Hypotheses around an unorthodox type of RNase P in human mitochondria

(2009) Johann Holzmann et al.   MITOCHONDRION

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

(2009) V. Rhein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular dynamics simulations of the amyloid-beta binding alcohol dehydrogenase (ABAD) enzyme

(2008) Alexandra T. Marques et al.   BIOORGANIC & MEDICINAL CHEMISTRY

RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

(2008) Johann Holzmann et al.   CELL

Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures

(2008) Yun-An Lim et al.   FEBS LETTERS

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

(2008) Anne Eckert et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

(2008) Anne Eckert et al.   Neurodegenerative Diseases