Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
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Title
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
Authors
Keywords
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Journal
MEDICINAL RESEARCH REVIEWS
Volume 34, Issue 2, Pages 340-437
Publisher
Wiley
Online
2013-06-06
DOI
10.1002/med.21290
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- A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation
- (2011) Gianpaolo Chiriano et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation
- (2011) Daniela Karlsson et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands
- (2011) Tim Kottke et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The antidepressant-like effect of Hedyosmum brasiliense and its sesquiterpene lactone, podoandin in mice: Evidence for the involvement of adrenergic, dopaminergic and serotonergic systems
- (2011) Ana Elisa Gonçalves et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pharmacokinetic evaluation of losartan
- (2011) Michel Burnier et al. Expert Opinion on Drug Metabolism & Toxicology
- Synthesis and antibacterial and antifungal studies of novel nitrogen containing heterocycles from 5-Ethylpyridin-2-ethanol
- (2011) NB Patel et al. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Synthesis, Crystal Structure, Spectroscopic, Magnetic, Theoretical, and Microbiological Studies of a Nickel(II) Complex ofl-Tyrosine and Imidazole, [Ni(Im)2(l-tyr)2]·4H2O
- (2011) Agnieszka Wojciechowska et al. INORGANIC CHEMISTRY
- En Route to Osmium Analogues of KP1019: Synthesis, Structure, Spectroscopic Properties and Antiproliferative Activity oftrans-[OsIVCl4(Hazole)2]
- (2011) Gabriel E. Büchel et al. INORGANIC CHEMISTRY
- In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species
- (2011) Manuel Sánchez-Moreno et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Synthesis, Characterization and Bioactivity Research of a Derivative of Secnidazole: 1-(2-Chloropropyl)-2-methyl-5-nitro-1H-imidazole
- (2011) Xi-Shou Huang et al. JOURNAL OF CHEMICAL CRYSTALLOGRAPHY
- Synthesis, antimicrobial and antimycobacterial evaluation of [2-(substituted phenyl)-imidazol-1-yl]-pyridin-3-yl-methanones
- (2011) Balasubramanian Narasimhan et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Design and Synthesis of Novel Arylpiperazine Derivatives Containing the Imidazole Core Targeting 5-HT2AReceptor and 5-HT Transporter
- (2011) Hee Jeong Seo et al. JOURNAL OF MEDICINAL CHEMISTRY
- Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141)
- (2011) Carl R. Illig et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Aromatase Inhibitors Selective over 17-α-Hydroxylase/C17−20 Lyase
- (2011) Angela Stefanachi et al. JOURNAL OF MEDICINAL CHEMISTRY
- In VivoTrypanosomicidal Activity of Imidazole- or Pyrazole-Based Benzo[g]phthalazine Derivatives against Acute and Chronic Phases of Chagas Disease
- (2011) Manuel Sánchez-Moreno et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates
- (2011) Mohamed S. Gomaa et al. JOURNAL OF MEDICINAL CHEMISTRY
- Triazole Ligands Reveal Distinct Molecular Features That Induce Histamine H4Receptor Affinity and Subtly Govern H4/H3Subtype Selectivity
- (2011) Maikel Wijtmans et al. JOURNAL OF MEDICINAL CHEMISTRY
- Irreversible Nek2 Kinase Inhibitors with Cellular Activity
- (2011) Jeffrey C. Henise et al. JOURNAL OF MEDICINAL CHEMISTRY
- Asymmetric Chemoenzymatic Synthesis of Miconazole and Econazole Enantiomers. The Importance of Chirality in Their Biological Evaluation
- (2011) Juan Mangas-Sánchez et al. JOURNAL OF ORGANIC CHEMISTRY
- Synthesis, Characterization of Some New Five Membered Heterocycles Based on Imidazole Moiety and their Applications on Therapeutics
- (2011) V. S.V. Satyanarayana et al. Letters in Drug Design & Discovery
- Synthesis and Antimycobacterial Evaluation of N-(E)-heteroaromaticpyrazine-2-carbohydrazide Derivatives
- (2011) C. H. S. Lima et al. Medicinal Chemistry
- An efficient and straight forward synthesis of (5S)-1-benzyl-5- (1H-imidazol-1-ylmethyl)-2-pyrrolidinone (MM1): a novel antihypertensive agent
- (2011) Jagdish Prasad et al. MEDICINAL CHEMISTRY RESEARCH
- Advances in metal–carbene complexes as potent anti-cancer agents
- (2011) Arnaud Gautier et al. Metallomics
- Group 11 Metal Compounds with Tripodal Bis(imidazole) Thioether Ligands. Applications as Catalysts in the Oxidation of Alkenes and as Antimicrobial Agents
- (2011) Fangwei Liu et al. MOLECULES
- Muscarine, imidazole, oxazole, and thiazole alkaloids
- (2011) Zhong Jin NATURAL PRODUCT REPORTS
- Rethinking amide bond synthesis
- (2011) Vijaya R. Pattabiraman et al. NATURE
- Imidazole-bearing tetraphenylethylene: fluorescent probe for metal ions based on AIE feature
- (2011) Ning Bian et al. NEW JOURNAL OF CHEMISTRY
- Inhibition of peroxynitrite- and peroxidase-mediated protein tyrosine nitration by imidazole-based thiourea and selenourea derivatives
- (2011) Krishna P. Bhabak et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Imidazole derivatives: A comprehensive survey of their recognition properties
- (2011) Pedro Molina et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Unique X-ray Sheet Structure of 1,8-Bis(imidazolium) Anthracene and Its Application as a Fluorescent Probe for DNA and DNase
- (2011) Ha Na Kim et al. ORGANIC LETTERS
- A Simple but Effective Dual Redox and Fluorescent Ion Pair Receptor Based on a Ferrocene−Imidazopyrene Dyad
- (2011) María Alfonso et al. ORGANIC LETTERS
- Polymeric materials with antimicrobial activity
- (2011) Alexandra Muñoz-Bonilla et al. PROGRESS IN POLYMER SCIENCE
- Synthesis and characterization of imidazolium telechelic poly(butylene terephthalate) for antimicrobial applications
- (2011) Martino Colonna et al. REACTIVE & FUNCTIONAL POLYMERS
- Synthesis, spectral and thermal studies of some transition metal mixed ligand complexes: Modeling of equilibrium composition and biological activity
- (2011) M.A. Neelakantan et al. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
- Fluorescence sensing of H2PO4- by a imidazolium-based cholestane receptor
- (2011) Jyoti Ramesh Jadhav et al. TETRAHEDRON LETTERS
- Novel DNA fluorescence probes based on 2-thioxo-tetrahydro-4H-imidazol-4-ones: synthetic and biological studies
- (2011) Alexander G. Majouga et al. TETRAHEDRON LETTERS
- Luminescent cyclometalated platinum(ii) complexes containing N-heterocyclic carbene ligands with potent in vitro and in vivo anti-cancer properties accumulate in cytoplasmic structures of cancer cells
- (2011) Raymond Wai-Yin Sun et al. Chemical Science
- Synthesis and biological evaluation of a new class of anti-brucella compounds targeting histidinol dehydrogenase: α-O-arylketones and α-S-arylketones derived from histidine
- (2011) François Turtaut et al. MedChemComm
- Design, synthesis and antiproliferative activity of urocanic-chalcone hybrid derivatives
- (2011) Alexander Ciupa et al. MedChemComm
- Supramolecular Ferric Porphyrins as Cyanide Receptors in Aqueous Solution
- (2011) Kenji Watanabe et al. ACS Medicinal Chemistry Letters
- Discovery of S-Nitrosoglutathione Reductase Inhibitors: Potential Agents for the Treatment of Asthma and Other Inflammatory Diseases
- (2011) Xicheng Sun et al. ACS Medicinal Chemistry Letters
- Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties
- (2010) Travis T. Wager et al. ACS Chemical Neuroscience
- Synthesis and anthelmintic activity of some novel 2-substituted-4,5-diphenyl imidazoles
- (2010) Satyajit Dutta ACTA PHARMACEUTICA
- Zinc–imidazole negative staining of chromosomal-sized DNA molecules in agarose minigels
- (2010) Karen León et al. ANALYTICAL BIOCHEMISTRY
- Thin-Film Formation of Imidazolium-Based Conjugated Polydiacetylenes and Their Application for Sensing Anionic Surfactants
- (2010) Xiaoqiang Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells
- (2010) Daniel V. LaBarbera et al. ANTI-CANCER DRUGS
- Anticancer activities of alkylating pyrrole–imidazole polyamides with specific sequence recognition
- (2010) Ken-Ichi Shinohara et al. ANTI-CANCER DRUGS
- Synthesis, cytotoxicity and antibacterial studies of symmetrically and non-symmetrically benzyl- or p-cyanobenzyl-substituted N-Heterocyclic carbene-silver complexes
- (2010) Siddappa Patil et al. APPLIED ORGANOMETALLIC CHEMISTRY
- N-methyl amine-substituted fluoxetine derivatives: New dopamine transporter inhibitors
- (2010) Young Sil Yoon et al. ARCHIVES OF PHARMACAL RESEARCH
- Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives
- (2010) Arzu Karakurt et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides
- (2010) Ahmed S. Aboraia et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Targeting the ICB2 site of the topoisomerase IIα promoter with a formamido-pyrrole–imidazole–pyrrole H-pin polyamide
- (2010) Andrew Franks et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of 4(5)-(6-methylpyridin-2-yl)imidazoles and -pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
- (2010) Dae-Kee Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and structure–activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor
- (2010) Makoto Ishikawa et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode
- (2010) Maris A. Cinelli et al. BIOORGANIC & MEDICINAL CHEMISTRY
- ‘Click chemistry’ synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase
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- Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds
- (2010) Dan Niculescu-Duvaz et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The evaluation of quinonoid compounds against Trypanosoma cruzi: Synthesis of imidazolic anthraquinones, nor-β-lapachone derivatives and β-lapachone-based 1,2,3-triazoles
- (2010) Eufrânio N. da Silva Júnior et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis of new antifungal peptides selective against Cryptococcus neoformans
- (2010) Manuela Grimaldi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents
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- Synthesis and SAR study of new phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phosphodiesterase 10A inhibitors
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- Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17α-hydroxylase/17,20-lyase (P45017α) derived from rat testicular microsomes
- (2010) Caroline P. Owen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials
- (2010) Xianming Deng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists
- (2010) Shuwen He et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity
- (2010) Jian Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells
- (2010) Haiyan Che et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of 2-pyridyl-substituted pyrazoles and imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors
- (2010) Purushottam M. Dewang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists
- (2010) Marie Grimstrup et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists
- (2010) János Galambos et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers
- (2010) Sriram Tyagarajan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1
- (2010) Tom Y.H. Wu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Tri- and tetrasubstituted imidazoles as p38α mitogen-activated protein kinase inhibitors
- (2010) Stefan Laufer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, crystal and antibacterial studies of diversely functionalized tetrahydropyridin-4-ol
- (2010) Gopalakrishnan Aridoss et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell lines
- (2010) Junghun Lee et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 1,4-Dihydropyrazolo[4,3-d]imidazole phenyl derivatives: A novel type II Raf kinase inhibitors
- (2010) Hana Yu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution
- (2010) Andrew Potter et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Benzimidazole and imidazole inhibitors of histone deacetylases: Synthesis and biological activity
- (2010) Jerome C. Bressi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: Azoles: Effective metal chelators
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- Synthesis, antibacterial and antifungal activities of some carbazole derivatives
- (2010) Fei-Fei Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists
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- A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit
- (2010) Timothy D. Cushing et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Compounds containing 2-substituted imidazole ring for treatment against human African trypanosomiasis
- (2010) Bhupesh S. Samant et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure–activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain
- (2010) Shu-Wei Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and preliminary evaluation of curcumin analogues as cytotoxic agents
- (2010) Qin Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diamide amino-imidazoles: A novel series of γ-secretase inhibitors for the treatment of Alzheimer’s disease
- (2010) Michael A. Brodney et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling
- (2010) Rudy Ciayadi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Substituted imidazole derivatives as novel cardiovascular agents
- (2010) Vineet Malhotra et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception
- (2010) Lalit Kumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand
- (2010) Shuo-Bin Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- An inhibitor-like binding mode of a carbonic anhydrase activator within the active site of isoform II
- (2010) Khyati Dave et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014
- (2010) Michael A. Brodney et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents
- (2010) Yuan Shi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Syntheses of ruthenium(II)-4,4′-biimidazole complexes and their potential anti-tumour activity
- (2010) David C. Kennedy et al. CANADIAN JOURNAL OF CHEMISTRY
- Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors
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- Polycyclic N-Heterocyclic Compounds. Part 64: Synthesis of 5-Amino-1,2,6,7-tetrahydrobenzo[f]furo[2,3-c]isoquinolines and Related Compounds. Evaluation of Their Bronchodilator Activity and Effects on Lipoprotein Lipase mRNA Expression
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- Antibacterial Activity of 5-Dialkylaminomethylhydantoins and Related Compounds
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- Electropolymerization of intercalator-grafted conducting polymer for direct and amplified DNA detection
- (2010) Natalia C. Tansil et al. CHEMICAL COMMUNICATIONS
- Fluoro- and Chromogenic Chemodosimeters for Heavy Metal Ion Detection in Solution and Biospecimens
- (2010) Duong Tuan Quang et al. CHEMICAL REVIEWS
- Revisit to imidazolium receptors for the recognition of anions: highlighted research during 2006–2009
- (2010) Zhaochao Xu et al. CHEMICAL SOCIETY REVIEWS
- Rational Design of Fluorescent Bioimaging Probes by Controlling the Aggregation Behavior of Squaraines: A Special Effect of Ionic Liquid Pendants
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- The Role of Fluorine Substitution in Biphenyl Methylene Imidazole-Type CYP17 Inhibitors for the Treatment of Prostate Carcinoma
- (2010) Qingzhong Hu et al. ChemMedChem
- Heme Oxygenase Inhibition by 1-Aryl-2-(1H-imidazol-1-yl/1H-1,2,4-triazol-1-yl)ethanones and Their Derivatives
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- Synthesis and Biological Testing of N-Aminoimidazole-Based p38α MAP Kinase Inhibitors
- (2010) Claudia Bracht et al. ChemMedChem
- Polyethylene glycol (PEG-400): An efficient and recyclable reaction medium for the synthesis of novel 1; 5-benzodiazepines and their antimicrobial activity
- (2010) Shankaraiah G. Konda et al. CHINESE CHEMICAL LETTERS
- Synthesis and Preliminary Screening of Novel Tryptamines as 5-HT4 Receptor Ligands
- (2010) A. Hanna-Elias et al. CURRENT MEDICINAL CHEMISTRY
- Thromboxane Synthase Inhibitors and Thromboxane A2 Receptor Antagonists: A Quantitative Structure Activity Relationships (QSARs) Analysis
- (2010) C. Kontogiorgis et al. CURRENT MEDICINAL CHEMISTRY
- Imidazolium Cations in Organic Chemistry: From Chemzymes to Supramolecular Building Blocs
- (2010) Nadim Noujeim et al. CURRENT ORGANIC CHEMISTRY
- Synthesis and bioassay of pyrrolyl oxazolines and thiazolines
- (2010) V. Padmavathi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of carbohydrate-conjugate heterobimetallic CuII–Sn2IV and ZnII–Sn2IV complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity
- (2010) Sartaj Tabassum et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis
- (2010) Mohammad A. Khanfar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Cytotoxicity and Topo I targeting activity of substituted 10--nitrogenous heterocyclic aromatic group derivatives of SN-38
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- Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents
- (2010) Bo Fang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl)phenyl]acetamide derivatives and evaluation of their anticancer activity
- (2010) Yusuf Özkay et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities
- (2010) Xian-Long Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles
- (2010) André P. Liesen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a novel nitroimidazolyl–oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation
- (2010) Ali Khalaj et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, Cytotoxicity and Antibacterial Studies of Novel Symmetrically and Nonsymmetrically 4-(Methoxycarbonyl)benzyl-Substituted N-Heterocyclic Carbene-Silver Acetate Complexes
- (2010) Siddappa Patil et al. HELVETICA CHIMICA ACTA
- Synthesis of Two Estradiol-Imidazole C-Ribonucleoside Hybrid Compounds Exhibiting Inhibitory Effects against Type 1 17β-Hydroxysteroid Dehydrogenase
- (2010) Shinya Harusawa et al. HETEROCYCLES
- Synthesis, spectroscopic characterization and radiosensitizing properties of acetato-bridged copper(II) complexes with 5-nitroimidazole drugs
- (2010) Ana Cecilia Valderrama-Negrón et al. INORGANICA CHIMICA ACTA
- A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro
- (2010) Linda A. Dunn et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents
- (2010) Wen-Tai Li et al. INVESTIGATIONAL NEW DRUGS
- Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities
- (2010) Lin Du et al. JOURNAL OF ANTIBIOTICS
- An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies
- (2010) George Agelis et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Synthesis, characterization, thermal and redox behavior, and biological activity of Ni(II), Cu(II), and Zn(II) complexes containing pyridoxine and imidazole moieties
- (2010) M.A. Neelakantan et al. JOURNAL OF COORDINATION CHEMISTRY
- Synthesis, characterization, antimicrobial, and nuclease activity studies of some metal Schiff-base complexes
- (2010) D. Arish et al. JOURNAL OF COORDINATION CHEMISTRY
- Synthesis and biological evaluation of novel 2-(4-O-β-D-glucosidoxyphenyl)-4,5-disubstituted imidazoles
- (2010) V. S. Taile et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands
- (2010) Mauro Ravera et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Rigid Analogues of the α2-Adrenergic Blocker Atipamezole: Small Changes, Big Consequences
- (2010) Bernard Vacher et al. JOURNAL OF MEDICINAL CHEMISTRY
- In Vitro and in Vivo Trypanocidal Evaluation of Nickel Complexes with an Azapurine Derivative againstTrypanosoma cruzi
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- Structure-Based Design, Synthesis, and Biological Studies of New Anticancer Norindenoisoquinoline Topoisomerase I Inhibitors
- (2010) Yunlong Song et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Evaluation of Dibenzo[c,h][1,6]naphthyridines as Topoisomerase I Inhibitors and Potential Anticancer Agents
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- Novel Highly Potent and Selective Nonsteroidal Aromatase Inhibitors: Synthesis, Biological Evaluation and Structure−Activity Relationships Investigation
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- Role of Hydrophobic Substituents on the Terminal Nitrogen of Histamine in Receptor Binding and Agonist Activity: Development of an Orally Active Histamine Type 3 Receptor Agonist and Evaluation of Its Antistress Activity in Mice
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- Structure-Based Design and Synthesis of Potent, Ethylenediamine-Based, Mammalian Farnesyltransferase Inhibitors as Anticancer Agents
- (2010) Steven Fletcher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents
- (2010) Jianjun Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB1Receptor Antagonism
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- Unexpected Reaction of 2-Alkylsulfanylimidazoles to Imidazol-2-ones: Pyridinylimidazol-2-ones as Novel Potent p38α Mitogen-Activated Protein Kinase Inhibitors
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- Synthesis and Biological Activities of 2-Amino-1-arylidenamino Imidazoles as Orally Active Anticancer Agents
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- Design, Synthesis and In Vitro Anticancer Activity of a New Class of Bifunctional DNA Intercalators
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- Synthesis of 5-Amino-3-methylimidazolidine-2,4-dione and 1,3,5-Triazine Derivatives as Analogues of the Alkaloids Naamidine A and G
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- Synthesis and biological evaluation of novel imidazole-containing macrocycles
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- Pseudoceratinazole A: a novel bromotyrosine alkaloid from the Australian sponge Pseudoceratina sp.
- (2010) Yunjiang Feng et al. TETRAHEDRON LETTERS
- Synthesis and antibacterial evaluation of 2–substituted–4,5–diphenyl–N–alkyl imidazole derivatives
- (2010) Abhishek K Jain et al. Asian Pacific Journal of Tropical Medicine
- Antivascular and anticancer activity of dihalogenated A-ring analogues of combretastatin A-4
- (2010) Thomas M. Beale et al. MedChemComm
- First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases
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- Effect of Sequence and Structural Properties on 14-Helical β-Peptide Activity againstCandida albicansPlanktonic Cells and Biofilms
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- Synthesis and Cytotoxic Activity of Novel Amidine Analogues of Bis(2-chloroethyl)amine
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- 3-Imidazolyl-Substituted Flavans as Potential Antifungal Agents: Synthesis, Stereochemical Properties, and Antifungal Activity
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- Synthesis andIn-VitroAnti-Hepatitis-B Virus Activity of 6H-[1]Benzothiopyrano[4,3-b] quinolin-10-ols
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- Synthesis, Antibacterial and Antifungal Activities of Novel 1,2,4-Triazolium Derivatives
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- Synthesis and evaluation of imidazole–dioxolane compounds as selective heme oxygenase inhibitors: Effect of substituents at the 4-position of the dioxolane ring
- (2009) Jason Z. Vlahakis et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of novel phthalazinone derivatives as topically active phosphodiesterase 4 inhibitors
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- Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity
- (2009) Rita C. Santos et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors
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- Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: Synthesis, pharmacological evaluation, and cross-target QSAR studies
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- Bulky 1,4-benzoxazine derivatives with antifungal activity
- (2009) Renata Fringuelli et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis, biological evaluation and molecular modelling studies of novel quinoline derivatives against Mycobacterium tuberculosis
- (2009) Ram Shankar Upadhayaya et al. BIOORGANIC & MEDICINAL CHEMISTRY
- 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A2α and fatty acid amide hydrolase
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- Cell permeability of Py–Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content
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- Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues
- (2009) Stéphanie Duez et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs
- (2009) Kouatli Omar et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design and synthesis of selective inhibitors of Placental Alkaline Phosphatase
- (2009) Marion Lanier et al. BIOORGANIC & MEDICINAL CHEMISTRY
- New small-size peptides possessing antifungal activity
- (2009) Francisco M. Garibotto et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes
- (2009) Perumal Rajakumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- (2-Aryl-5-methylimidazol-4-ylcarbonyl)guanidines and (2-aryl-5-methyloxazol-4-ylcarbonyl)guanidines as NHE-1 inhibitors
- (2009) Sunkyung Lee et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and cytotoxic activities of novel phenacylimidazolium bromides
- (2009) Xiao-Dong Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Small molecule antagonists of the gonadotropin-releasing hormone (GnRH) receptor: Structure–activity relationships of small heterocyclic groups appended to the 2-phenyl-4-piperazinyl-benzimidazole template
- (2009) Diane B. Hauze et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates
- (2009) Dorota Łażewska et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties
- (2009) Neil Moss et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17α-hydroxylase/17,20-lyase (P-45017α)
- (2009) Sabbir Ahmed et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: Potent, orally-active 1,4-disubstituted imidazoles
- (2009) Robert L. Dow et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer’s disease
- (2009) Christopher J. Helal et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model
- (2009) Barbara Attenni et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles and 1,3,5-trisubstituted pyrazoles as inhibitors of transforming growth factor β type 1 receptor (ALK5)
- (2009) Xingzhou Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of imidazole derivatives as novel NOP/ORL1 receptor antagonists: Exploration and optimization of alternative pyrazole structure
- (2009) Yuichi Sugimoto et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis
- (2009) Daniele Castagnolo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors
- (2009) Kohsuke Asoh et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of biaryl inhibitors of H+/K+ ATPase
- (2009) Neil Garton et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies
- (2009) Jos H.M. Lange et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of C-imidazole azaheptapyridine FPT inhibitors
- (2009) Hugh Y. Zhu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2
- (2009) Marie Grimstrup et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis of substituted aryloxy alkyl and aryloxy aryl alkyl imidazoles as antileishmanial agents
- (2009) Kalpana Bhandari et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A profile of the in vitro anti-tumor activity of imidazolium-based ionic liquids
- (2009) Sanjay V. Malhotra et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The role of histamine H4 receptor in immune and inflammatory disorders
- (2009) E Zampeli et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel Microtubule Polymerization Inhibitor with Potent Antiproliferative and Antitumor Activity
- (2009) S. Arora et al. CANCER RESEARCH
- Design of Conformationally Constrained Azole Antifungals: Efficient Synthesis and Antifungal Activity oftrans-3-Imidazolylflavanones
- (2009) Saeed Emami et al. Chemical Biology & Drug Design
- Chemistry and Biology of Synthetic and Naturally Occurring Antiamoebic Agents†
- (2009) Shailendra Singh et al. CHEMICAL REVIEWS
- DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
- (2009) Yves Pommier CHEMICAL REVIEWS
- The Medicinal Applications of Imidazolium Carbene−Metal Complexes
- (2009) Khadijah M. Hindi et al. CHEMICAL REVIEWS
- Platinum Drug Distribution in Cancer Cells and Tumors
- (2009) Alice V. Klein et al. CHEMICAL REVIEWS
- Impact of Natural Products on Developing New Anti-Cancer Agents†
- (2009) Gordon M. Cragg et al. CHEMICAL REVIEWS
- (Thio)urea organocatalysis—What can be learnt from anion recognition?
- (2009) Zhiguo Zhang et al. CHEMICAL SOCIETY REVIEWS
- 2-Acylaminopyridin-4-ylimidazoles as p38 MAP Kinase Inhibitors: Design, Synthesis, and Biological and Metabolic Evaluations
- (2009) Katharina Ziegler et al. ChemMedChem
- New Antimicrobial Hexapeptides: Synthesis, Antimicrobial Activities, Cytotoxicity, and Mechanistic Studies
- (2009) Rohitâ K. Sharma et al. ChemMedChem
- Study on the synthesis and antimicrobial activity of novel cationic porphyrins
- (2009) Ke Gui Yu et al. CHINESE CHEMICAL LETTERS
- Role of Copper in Angiogenesis and Its Medicinal Implications
- (2009) Huiqi Xie et al. CURRENT MEDICINAL CHEMISTRY
- Copper Compounds in Anticancer Strategies
- (2009) Saverio Tardito et al. CURRENT MEDICINAL CHEMISTRY
- Antifungal Carbazoles
- (2009) Karin Thevissen et al. CURRENT MEDICINAL CHEMISTRY
- Metal Complexes, their Cellular Targets and Potential for Cancer Therapy
- (2009) Di Chen et al. CURRENT PHARMACEUTICAL DESIGN
- Imidazole-based phosphane gold(I) complexes as potential agents for cancer treatment: Synthesis, structural studies and antitumour activity
- (2009) Peter C. Kunz et al. DALTON TRANSACTIONS
- Areneruthenium complexes as anticancer agents
- (2009) Georg Süss-Fink DALTON TRANSACTIONS
- Synthesis and in vitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide(sulfonamide)-2-methyl-4-nitro-1H-imidazoles☆
- (2009) Emanuel Hernández-Núñez et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, spectral and biological evaluation of some new thiazolidinones and thiazoles based on t-3-alkyl-r-2,c-6-diarylpiperidin-4-ones
- (2009) G. Aridoss et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anti-oxidant, anti-fungal and anti-leishmanial activities of novel 3-[4-(1H-imidazol-1-yl) phenyl]prop-2-en-1-ones
- (2009) Tanvir Hussain et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N3,N5-bisaryl-1,4-dihydropyridine-3,5-dicarboxamides
- (2009) Afshin Fassihi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antitubercular screening of imidazole derivatives☆
- (2009) Jyoti Pandey et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives
- (2009) Sham M. Sondhi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety
- (2009) M.A. Gouda et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Histamine H3and H4receptors as novel drug targets
- (2009) Ekaterini Tiligada et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer
- (2009) Jean-Marc Nabholtz et al. EXPERT OPINION ON PHARMACOTHERAPY
- Increased potency of a novel d-β-naphthylalanine-substituted antimicrobial peptide against âfluconazole-resistant âfungal pathogens
- (2009) Chih-Wei Wang et al. FEMS YEAST RESEARCH
- [OsIVCl5(Hazole)]−Complexes: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity
- (2009) Gabriel E. Büchel et al. INORGANIC CHEMISTRY
- Synthesis and Quantitative Structure−Antifungal Activity Relationships of Clovane Derivatives against Botrytis cinerea†
- (2009) Liane Saiz-Urra et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Studies on mode of action of hexaammine co(III) chloride against diethylnitrosamine-induced hepatocarcinogenesis in mice
- (2009) Amarjit S. Naura et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Anion effects on anti-microbial activity of poly[1-vinyl-3-(2-sulfoethyl imidazolium betaine)]
- (2009) Godawari Garg et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Imidazole-containing farnesyltransferase inhibitors: 3D quantitative structure–activity relationships and molecular docking
- (2009) Aihua Xie et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Synthesis of imidazole-containing analogues of farnesyl pyrophosphate and evaluation of their biological activity on protein farnesyltransferase
- (2009) Laëtitia Coudray et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- New imidazole derivatives of 2(3H)-benzazolones as potential antifungal agents
- (2009) Ognyan Petrov et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Spectroscopic study of the interaction of NiII-5-triethyl ammonium methyl salicylidene ortho-phenylendiiminate with native DNA
- (2009) Giampaolo Barone et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Synthesis, characterization and biological activities of mononuclear Co(III) complexes as potential bioreductively activated prodrugs
- (2009) Elizabeth Teixeira Souza et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4Receptor Agonists§
- (2009) Patrick Igel et al. JOURNAL OF MEDICINAL CHEMISTRY
- Vascular Disrupting Activity of Tubulin-Binding 1,5-Diaryl-1H-imidazoles†
- (2009) Katiuscia Bonezzi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships
- (2009) Yan Lu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel, Potent, and Selective Quinoxaline-Based 5-HT3Receptor Ligands. 1. Further Structure−Activity Relationships and Pharmacological Characterization
- (2009) Stefania Butini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of 2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an Active Metabolite. A Novel, Potent and Selective Cannabinoid-1 Receptor Inverse Agonist with High Antiobesity Efficacy in DIO Mice
- (2009) Chien-Huang Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Role of the Hydrogen Bonding Heteroatom−Lys53 Interaction between the p38α Mitogen-Activated Protein (MAP) Kinase and Pyridinyl-Substituted 5-Membered Heterocyclic Ring Inhibitors
- (2009) Bassam Abu Thaher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Electrochemistry of 2-Ethenyl and 2-Ethanyl Derivatives of 5-Nitroimidazole and Antimicrobial Activity againstGiardia lamblia
- (2009) Carlos A. Valdez et al. JOURNAL OF MEDICINAL CHEMISTRY
- A DFT study on the hydrolysis mechanism of the potential antitumor Ru(III) complex TzNAMI
- (2009) Jin-Can Chen et al. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
- Determination of the Förster Distance in Polymer Films by Fluorescence Decay for Donor Dyes with a Nonexponential Decay Profile
- (2009) Neda Felorzabihi et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Pharmacophore Searching of Benzofuran Derivatives for Selective CYP19 Aromatase Inhibition
- (2009) Shuchi Nagar et al. Letters in Drug Design & Discovery
- Synthesis and Biochemical Evaluation of a Range of 2-, 3- and 4-Substituted Derivatives of Benzyl Imidazole-Based Compounds as Probes of the Active Site of 17α-hydroxylase/17,20-Lyase (P45017α)
- (2009) Sabbir Ahmed et al. Letters in Drug Design & Discovery
- A Submarine Journey: The Pyrrole-Imidazole Alkaloids
- (2009) Barbara Forte et al. Marine Drugs
- In vitroantifungal activities of luliconazole, a new topical imidazole
- (2009) Hiroyasu Koga et al. MEDICAL MYCOLOGY
- Synthesis of novel Hantzsch dihydropyridines and Biginelli dihydropyrimidines of biological interest: a 3D-QSAR study on their cytotoxicity
- (2009) B. R. Prashantha Kumar et al. MEDICINAL CHEMISTRY RESEARCH
- Recent developments in anti-inflammatory natural products
- (2009) Raju Gautam et al. MEDICINAL RESEARCH REVIEWS
- Antibiotics: Natural products essential to human health
- (2009) Arnold L. Demain MEDICINAL RESEARCH REVIEWS
- Recent developments in ruthenium anticancer drugs
- (2009) Aviva Levina et al. Metallomics
- The indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives
- (2009) Y. Pommier et al. MOLECULAR CANCER THERAPEUTICS
- Classical and 3D-QSAR studies of cytochrome 17 inhibitor imidazole-substituted biphenyls
- (2009) Partha Pratim Roy et al. MOLECULAR SIMULATION
- Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
- (2009) Abdul Jabar Kh. Atia MOLECULES
- Muscarine, imidazole, oxazole and thiazole alkaloids
- (2009) Zhong Jin NATURAL PRODUCT REPORTS
- Porphyrin-linked nitroimidazole antibiotics targeting Porphyromonas gingivalis
- (2009) Benjamin C.-M. Yap et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites
- (2009) Alessandro Baliani et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- New asymmetric synthesis of protein farnesyltransferase inhibitors via palladium-catalyzed cross-coupling reactions of 2-iodo-imidazoles
- (2009) Jennifer Kerhervé et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Mercury Complexes of N-Heterocyclic Carbenes Derived from Imidazolium-Linked Cyclophanes: Synthesis, Structure, and Reactivity
- (2009) Murray V. Baker et al. ORGANOMETALLICS
- Evaluation of the antimicrobial activity of some chloro complexes of imidazole-2-carbaldehyde semicarbazone: X-ray crystal structure of cis-NiCl2(H2L)(H2O)
- (2009) María C. Rodríguez-Argüelles et al. POLYHEDRON
- Synthesis, characterization, DNA interaction studies and anticancer activity of platinum–clotrimazole complexes
- (2009) Maribel Navarro et al. TRANSITION METAL CHEMISTRY
- Review on supermolecules as chemical drugs
- (2009) ChengHe Zhou et al. Science in China. Series B, Chemistry
- Antifungal and Antibacterial Activity of the Newly Synthesized 2-Xanthone Derivatives
- (2008) Henryk Marona et al. ARCHIV DER PHARMAZIE
- Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors
- (2008) Rosanna Filosa et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and antitumor activity of novel 20s-camptothecin analogues
- (2008) Qingyong Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists
- (2008) Jong Yup Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Aryloxy cyclohexyl imidazoles: A novel class of antileishmanial agents
- (2008) Nagarapu Srinivas et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity
- (2008) Stephen P. East et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Anion receptors that contain metals as structural units
- (2008) Valeria Amendola et al. CHEMICAL COMMUNICATIONS
- From Natural Products to Small Molecule Ketone Histone Deacetylase Inhibitors: Development of New Class Specific Agents
- (2008) Philip Jones et al. CURRENT PHARMACEUTICAL DESIGN
- Topical Fenticonazole in Dermatology and Gynaecology
- (2008) Stefano Veraldi et al. DRUGS
- Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents
- (2008) Perumal Rajakumar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Convenient one-pot synthesis of novel 2-substituted benzimidazoles, tetrahydrobenzimidazoles and imidazoles and evaluation of their in vitro antibacterial and antifungal activities
- (2008) Shweta Sharma et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Penetratin and derivatives acting as antifungal agents
- (2008) Marcelo F. Masman et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: Antimicrobial, analgesic and antipyretic studies
- (2008) G. Aridoss et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives
- (2008) Arijit Basu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors
- (2008) Dae-Kee Kim et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Tetrahydronaphthyl azole oxime ethers: The conformationally rigid analogues of oxiconazole as antibacterials☆
- (2008) Kalpana Bhandari et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives
- (2008) Deepika Sharma et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, characterization and antimicrobial activity of transition metal complexes with the Schiff base derived from imidazole-2-carboxaldehyde and glycylglycine
- (2008) R. Selwin Joseyphus et al. JOURNAL OF COORDINATION CHEMISTRY
- Design and synthesis of substituted imidazole and triazoleN-phenylbenzo[d]oxazolamine inhibitors of retinoic acid metabolizing enzyme CYP26
- (2008) Stephane Pautus et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
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