Synthesis of Two Estradiol-Imidazole C-Ribonucleoside Hybrid Compounds Exhibiting Inhibitory Effects against Type 1 17β-Hydroxysteroid Dehydrogenase

Efficient Synthesis of 2’-O-Cyanoethylated Imidazole C-Ribonucleoside Phosphoramidite: A Practical Building Block for Probing the Catalytic Mechanism of Ribozymes

(2010) Shinya Harusawa et al.   HETEROCYCLES

Design, chemical synthesis, and in vitro biological evaluation of simplified estradiol–adenosine hybrids as inhibitors of 17β-hydroxysteroid dehydrogenase type 1

(2009) Marie Bérubé et al.   CANADIAN JOURNAL OF CHEMISTRY

Synthesis of Novel C4-Linked C2-Imidazole Ribonucleoside Phosphoramidite and Its Application to Probing the Catalytic Mechanism of a Ribozyme

(2009) Lisa Araki et al.   JOURNAL OF ORGANIC CHEMISTRY

Expression, Purification, and Characterization of a Human Recombinant 17β-Hydroxysteroid Dehydrogenase Type 1 in Escherichia coli

(2009) Yi-Hsun Chang et al.   MOLECULAR BIOTECHNOLOGY

Design and validation of specific inhibitors of 17 -hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis

(2008) J. M Day et al.   ENDOCRINE-RELATED CANCER

Design and synthesis of bisubstrate inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Overview and perspectives

(2008) D. Fournier et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Improved synthesis of EM-1745, preparation of its C17-ketone analogue and comparison of their inhibitory potency on 17β-hydroxysteroid dehydrogenase type 1

(2008) Marie Bérubé et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY