Rethinking amide bond synthesis

Protein Chemical Synthesis by Ligation of Peptide Hydrazides

(2011) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalysed approaches to amide bond formation

(2011) C. Liana Allen et al.   CHEMICAL SOCIETY REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct Synthesis of Polyamides via Catalytic Dehydrogenation of Diols and Diamines

(2011) Hanxiang Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of human GLP-1 (7–36) by chemoselective α-ketoacid–hydroxylamine peptide ligation of unprotected fragments

(2011) Jian Wu et al.   Chemical Science

Total Chemical Synthesis of Di-ubiquitin Chains

(2010) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

(2010) Richard J. Clark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Insights into Direct Amide Bond Formation Catalyzed by Boronic Acids: Halogens as Lewis Bases

(2010) Tommaso Marcelli   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward fully synthetic, homogeneous glycoproteins: Advances in chemical ligation

(2010) Yu Yuan et al.   BIOPOLYMERS

Invited reviewligation-Desulfurization: A powerful combination in the synthesis of peptides and glycopeptides

(2010) Heike Rohde et al.   BIOPOLYMERS

The thermal and boron-catalysed direct amide formation reactions: mechanistically understudied yet important processes

(2010) Hayley Charville et al.   CHEMICAL COMMUNICATIONS

Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine

(2010) Renliang Yang et al.   CHEMICAL COMMUNICATIONS

Isolation, Sequencing, and Structure−Activity Relationships of Cyclotides

(2010) David C. Ireland et al.   JOURNAL OF NATURAL PRODUCTS

Direct Amide Synthesis from Either Alcohols or Aldehydes with Amines: Activity of Ru(II) Hydride and Ru(0) Complexes

(2010) Senthilkumar Muthaiah et al.   JOURNAL OF ORGANIC CHEMISTRY

Glycopolypeptides via Living Polymerization of Glycosylated-l-lysineN-Carboxyanhydrides

(2010) Jessica R. Kramer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Cyclosporine: Access to N-Methylated Peptides via Isonitrile Coupling Reactions

(2010) Xiangyang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Promising General Solution to the Problem of Ligating Peptides and Glycopeptides

(2010) Ping Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyamides - Still Strong After Seventy Years

(2010) Keith Marchildon   Macromolecular Reaction Engineering

Umpolung reactivity in amide and peptide synthesis

(2010) Bo Shen et al.   NATURE

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

(2010) Satpal Virdee et al.   Nature Chemical Biology

Nitrone protecting groups for enantiopure N-hydroxyamino acids: synthesis of N-terminal peptide hydroxylamines for chemoselective ligations

(2010) S. Irene Medina et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Oxidative Amidation and Azidation of Aldehydes by NHC Catalysis

(2010) Suman De Sarkar et al.   ORGANIC LETTERS

Salicylaldehyde Ester-Induced Chemoselective Peptide Ligations: Enabling Generation of Natural Peptidic Linkages at the Serine/Threonine Sites

(2010) Xuechen Li et al.   ORGANIC LETTERS

Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex-Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods

(2009) Kiriko Hirano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile synthesis of N-glycosyl amides using a N-glycosyl-2,4-dinitrobenzenesulfonamide and thioacids

(2009) Rommel S. Talan et al.   CARBOHYDRATE RESEARCH

Transition Metal-Catalyzed Living Radical Polymerization: Toward Perfection in Catalysis and Precision Polymer Synthesis

(2009) Makoto Ouchi et al.   CHEMICAL REVIEWS

Insights into the Biosynthesis and Stability of the Lasso Peptide Capistruin

(2009) Thomas A. Knappe et al.   CHEMISTRY & BIOLOGY

The Structure and Biological Aspects of Peptide Antibiotic Microcin J25

(2009) Paula Vincent et al.   CURRENT MEDICINAL CHEMISTRY

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

Synthesis of Small Glycopeptides by Decarboxylative Condensation and Insight into the Reaction Mechanism

(2009) Aditya K. Sanki et al.   JOURNAL OF ORGANIC CHEMISTRY

Thio FCMA Intermediates as Strong Acyl Donors: A General Solution to the Formation of Complex Amide Bonds

(2009) Yu Rao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Transamidation Reactions Compatible with Tertiary Amide Metathesis under Ambient Conditions

(2009) Nickeisha A. Stephenson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

What recent ribosome structures have revealed about the mechanism of translation

(2009) T. Martin Schmeing et al.   NATURE

Reaction of Thioacids with Isocyanates and Isothiocyanates: A Convenient Amide Ligation Process

(2009) David Crich et al.   ORGANIC LETTERS

Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods

(2009) Kalyaneswar Mandal et al.   PROTEIN SCIENCE

N-Methylation of Peptides: A New Perspective in Medicinal Chemistry

(2008) Jayanta Chatterjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

(2008) Juan B. Blanco-Canosa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Peptide Cyclization by Traceless Staudinger Ligation

(2008) Rolf Kleineweischede et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct and Waste-Free Amidations and Cycloadditions by Organocatalytic Activation of Carboxylic Acids at Room Temperature

(2008) Raed M. Al-Zoubi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Oxidative Esterification and Amidation of Aldehydes

(2008) Kekeli Ekoue-Kovi et al.   CHEMISTRY-A EUROPEAN JOURNAL

ChemoselectiveN-Acylation via Condensations ofN-(Benzoyloxy)amines and α-Ketophosphonic Acids under Aqueous Conditions

(2008) Jasbir Singh Arora et al.   JOURNAL OF ORGANIC CHEMISTRY

Mirror Image Forms of Snow Flea Antifreeze Protein Prepared by Total Chemical Synthesis Have Identical Antifreeze Activities

(2008) Brad L. Pentelute et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Chemistry with Old Functional Groups: On the Reaction of Isonitriles with Carboxylic Acids—A Route to Various Amide Types

(2008) Xuechen Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide Synthesis from Alcohols and Amines by the Extrusion of Dihydrogen

(2008) Lars Ulrik Nordstrøm et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dehydrative condensation catalyses

(2008) Kazuaki Ishihara   TETRAHEDRON