N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects
Authors
Keywords
-
Journal
PROTEOMICS
Volume 15, Issue 14, Pages 2385-2401
Publisher
Wiley
Online
2015-04-24
DOI
10.1002/pmic.201400619
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases
- (2015) Petra Van Damme et al. PROTEOMICS
- Developmental roles of protein N-terminal acetylation
- (2015) Rui D. Silva et al. PROTEOMICS
- The Molecular Basis for Histone H4- and H2A-Specific Amino-Terminal Acetylation by NatD
- (2015) Robert S. Magin et al. STRUCTURE
- An Organellar Nα-Acetyltransferase, Naa60, Acetylates Cytosolic N Termini of Transmembrane Proteins and Maintains Golgi Integrity
- (2015) Henriette Aksnes et al. Cell Reports
- De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females
- (2014) Bernt Popp et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects
- (2014) Line M. Myklebust et al. HUMAN MOLECULAR GENETICS
- α-N-Methylation of Damaged DNA-binding Protein 2 (DDB2) and Its Function in Nucleotide Excision Repair
- (2014) Qian Cai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A splice donor mutation inNAA10results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome
- (2014) Taraneh Esmailpour et al. JOURNAL OF MEDICAL GENETICS
- ASaccharomyces cerevisiaeModel RevealsIn VivoFunctional Impairment of the Ogden Syndrome N-Terminal Acetyltransferase NAA10 Ser37Pro Mutant
- (2014) Petra Van Damme et al. MOLECULAR & CELLULAR PROTEOMICS
- Wagging a tail at ubiquitin
- (2014) Tanja Mittag et al. Nature Chemical Biology
- Intrinsic disorder drives N-terminal ubiquitination by Ube2w
- (2014) Vinayak Vittal et al. Nature Chemical Biology
- New roles for old modifications: Emerging roles of N-terminal post-translational modifications in development and disease
- (2014) John G. Tooley et al. PROTEIN SCIENCE
- The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions
- (2014) Daniel J. Gibbs et al. TRENDS IN CELL BIOLOGY
- Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding
- (2014) William M. Holmes et al. Nature Communications
- Global profiling of co- and post-translationally N-myristoylated proteomes in human cells
- (2014) Emmanuelle Thinon et al. Nature Communications
- Design, Synthesis, and Kinetic Characterization of Protein N-Terminal Acetyltransferase Inhibitors
- (2013) Håvard Foyn et al. ACS Chemical Biology
- NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
- (2013) Janusz J. Petkowski et al. BIOCHEMICAL JOURNAL
- Ube2W conjugates ubiquitin to α-amino groups of protein N-termini
- (2013) Michael H. Tatham et al. BIOCHEMICAL JOURNAL
- The complexity of recognition of ubiquitinated substrates by the 26S proteasome
- (2013) Aaron Ciechanover et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The N-Terminal Methionine of Cellular Proteins as a Degradation Signal
- (2013) Heon-Ki Kim et al. CELL
- The Ubiquitin-conjugating Enzyme (E2) Ube2w Ubiquitinates the N Terminus of Substrates
- (2013) Kenneth Matthew Scaglione et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-terminal Acetylation Stabilizes N-terminal Helicity in Lipid- and Micelle-bound α-Synuclein and Increases Its Affinity for Physiological Membranes
- (2013) Igor Dikiy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Novel α-N-Methylation of CENP-B That Regulates Its Binding to the Centromeric DNA
- (2013) Xiaoxia Dai et al. JOURNAL OF PROTEOME RESEARCH
- Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway
- (2013) Anna Shemorry et al. MOLECULAR CELL
- Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
- (2013) Glen Liszczak et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog
- (2013) Glen Liszczak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Posttranslational modification of CENP-A influences the conformation of centromeric chromatin
- (2013) A. O. Bailey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- N-Terminal methylation of proteasome subunit Rpt1 in yeast
- (2013) Yayoi Kimura et al. PROTEOMICS
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- N-alpha-terminal Acetylation of Histone H4 Regulates Arginine Methylation and Ribosomal DNA Silencing
- (2013) Vassia Schiza et al. PLoS Genetics
- The N-End Rule Pathway
- (2012) Takafumi Tasaki et al. Annual Review of Biochemistry
- The Ubiquitin System, an Immense Realm
- (2012) Alexander Varshavsky Annual Review of Biochemistry
- HUWE1 ubiquitinates MyoD and targets it for proteasomal degradation
- (2012) Tahel Noy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Substrate Specificity of Mammalian N-Terminal α-Amino Methyltransferase NRMT
- (2012) Janusz J. Petkowski et al. BIOCHEMISTRY
- Human Protein N-terminal Acetyltransferase hNaa50p (hNAT5/hSAN) Follows Ordered Sequential Catalytic Mechanism
- (2012) Rune H. Evjenth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein N-terminal Acetyltransferases Act as N-terminal PropionyltransferasesIn VitroandIn Vivo
- (2012) Håvard Foyn et al. MOLECULAR & CELLULAR PROTEOMICS
- Protein N-terminal acetyltransferases in cancer
- (2012) T V Kalvik et al. ONCOGENE
- N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB
- (2012) P. Van Damme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein N-terminal acetyltransferases: when the start matters
- (2012) Kristian K. Starheim et al. TRENDS IN BIOCHEMICAL SCIENCES
- Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency
- (2011) Alan F. Rope et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation
- (2011) Glen Liszczak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bioinformatics Analysis of aSaccharomyces cerevisiaeN-Terminal Proteome Provides Evidence of Alternative Translation Initiation and Post-Translational N-Terminal Acetylation
- (2011) Kenny Helsens et al. JOURNAL OF PROTEOME RESEARCH
- Proteome-derived Peptide Libraries Allow Detailed Analysis of the Substrate Specificities of Nα-acetyltransferases and Point to hNaa10p as the Post-translational Actin Nα-acetyltransferase
- (2011) Petra Van Damme et al. MOLECULAR & CELLULAR PROTEOMICS
- The Human N-Alpha-Acetyltransferase 40 (hNaa40p/hNatD) Is Conserved from Yeast and N-Terminally Acetylates Histones H2A and H4
- (2011) Kristine Hole et al. PLoS One
- The N-end rule pathway and regulation by proteolysis
- (2011) Alexander Varshavsky PROTEIN SCIENCE
- N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex
- (2011) D. C. Scott et al. SCIENCE
- N-Terminal Acetylation Inhibits Protein Targeting to the Endoplasmic Reticulum
- (2011) Gabriella M. A. Forte et al. PLOS BIOLOGY
- NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation
- (2011) Petra Van Damme et al. PLoS Genetics
- Identification of Protein N-Terminal Methyltransferases in Yeast and Humans
- (2010) Kristofor J. Webb et al. BIOCHEMISTRY
- Protein N-Terminal Processing: Substrate Specificity ofEscherichia coliand Human Methionine Aminopeptidases
- (2010) Qing Xiao et al. BIOCHEMISTRY
- Post-translational myristoylation: Fat matters in cellular life and death
- (2010) Dale D.O. Martin et al. BIOCHIMIE
- Suppression of Human Immunodeficiency Virus Type-1 Production by Coexpression of Catalytic-Region-Deleted N-Myristoyltransferase Mutants
- (2010) Nobutoki Takamune et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Profiling ofN-Acetylated Protein Termini Provides In-depth Insights into the N-terminal Nature of the Proteome
- (2010) Andreas O. Helbig et al. MOLECULAR & CELLULAR PROTEOMICS
- The Chaperone-Like Protein HYPK Acts Together with NatA in Cotranslational N-Terminal Acetylation and Prevention of Huntingtin Aggregation
- (2010) T. Arnesen et al. MOLECULAR AND CELLULAR BIOLOGY
- NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein
- (2010) Christine E. Schaner Tooley et al. NATURE
- N-myristoylated proteins, key components in intracellular signal transduction systems enabling rapid and flexible cell responses
- (2010) Nobuhiro HAYASHI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system
- (2010) Takashi Suzuki et al. PROTEOMICS
- N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals
- (2010) C.-S. Hwang et al. SCIENCE
- Human Naa50p (Nat5/San) Displays Both ProteinNα- andNϵ-Acetyltransferase Activity
- (2009) Rune Evjenth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A proteomics approach to study in vivo protein Nα-modifications
- (2009) Xumin Zhang et al. Journal of Proteomics
- Knockdown of Human N -Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization
- (2009) K. K. Starheim et al. MOLECULAR AND CELLULAR BIOLOGY
- Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
- (2009) T. Arnesen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cotranslational processing mechanisms: towards a dynamic 3D model
- (2009) Carmela Giglione et al. TRENDS IN BIOCHEMICAL SCIENCES
- Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster
- (2009) Sandra Goetze et al. PLOS BIOLOGY
- Identification of the humanNα-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression
- (2008) Kristian K. Starheim et al. BIOCHEMICAL JOURNAL
- Hhat Is a Palmitoylacyltransferase with Specificity forN-Palmitoylation of Sonic Hedgehog
- (2008) John A. Buglino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1
- (2008) Yi Hao et al. JOURNAL OF CELL BIOLOGY
- Crystal structure of RimI fromSalmonella typhimurium LT2, the GNAT responsible for Nα-acetylation of ribosomal protein S18
- (2008) Matthew W. Vetting et al. PROTEIN SCIENCE
- Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog
- (2007) Dale D. O. Martin et al. FASEB JOURNAL
- Yeast Nα-terminal acetyltransferases are associated with ribosomes
- (2007) Bogdan Polevoda et al. JOURNAL OF CELLULAR BIOCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now