Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding

Amyloid-associated activity contributes to the severity and toxicity of a prion phenotype

(2014) John A. Pezza et al.   Nature Communications

Potential Involvement of N-Terminal Acetylation in the Quantitative Regulation of the ε Subunit of Chloroplast ATP Synthase under Drought Stress

(2013) Saki HOSHIYASU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The N-Terminal Methionine of Cellular Proteins as a Degradation Signal

(2013) Heon-Ki Kim et al.   CELL

The nascent polypeptide-associated complex is a key regulator of proteostasis

(2013) Janine Kirstein-Miles et al.   EMBO JOURNAL

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle

(2013) Nadia Arnaudo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nα-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain

(2013) Dongxue Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein

(2013) Theodore A. Sarafian et al.   PLoS One

Mechanistic Insight into the Relationship between N-Terminal Acetylation of α-Synuclein and Fibril Formation Rates by NMR and Fluorescence

(2013) Lijuan Kang et al.   PLoS One

N-alpha-terminal Acetylation of Histone H4 Regulates Arginine Methylation and Ribosomal DNA Silencing

(2013) Vassia Schiza et al.   PLoS Genetics

Characterization of Semisynthetic and NaturallyNα-Acetylated α-Synucleinin Vitroand in Intact Cells

(2012) Bruno Fauvet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SPINE-D: Accurate Prediction of Short and Long Disordered Regions by a Single Neural-Network Based Method

(2012) Tuo Zhang et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Linking Post-Translational Modifications and Variation of Phenotypic Traits

(2012) Warren Albertin et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein N-terminal acetyltransferases in cancer

(2012) T V Kalvik et al.   ONCOGENE

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

(2012) Lijuan Kang et al.   PROTEIN SCIENCE

Protein N-terminal acetyltransferases: when the start matters

(2012) Kristian K. Starheim et al.   TRENDS IN BIOCHEMICAL SCIENCES

Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency

(2011) Alan F. Rope et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival

(2011) Caroline H. Yi et al.   CELL

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

(2011) Tim Bartels et al.   NATURE

Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

(2011) Susanne DiSalvo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method

(2011) Annika Öhrfelt et al.   NEUROCHEMICAL RESEARCH

Towards a Functional Understanding of Protein N-Terminal Acetylation

(2011) Thomas Arnesen   PLOS BIOLOGY

N-Terminal Acetylation Inhibits Protein Targeting to the Endoplasmic Reticulum

(2011) Gabriella M. A. Forte et al.   PLOS BIOLOGY

The prion hypothesis: from biological anomaly to basic regulatory mechanism

(2010) Mick F. Tuite et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The effect of N-terminal acetylation on the structure of an N-terminal tropomyosin peptide and αα-tropomyosin

(2010) Norma J. Greenfield et al.   PROTEIN SCIENCE

A Size Threshold Limits Prion Transmission and Establishes Phenotypic Diversity

(2010) Aaron Derdowski et al.   SCIENCE

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

(2009) T. Arnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

(2009) Sandra Goetze et al.   PLOS BIOLOGY

The NatA Acetyltransferase Couples Sup35 Prion Complexes to the [PSI+] Phenotype

(2008) John A. Pezza et al.   MOLECULAR BIOLOGY OF THE CELL

Implementation of GenePattern within the Stanford Microarray Database

(2008) J. Hubble et al.   NUCLEIC ACIDS RESEARCH

Extent of N-terminal modifications in cytosolic proteins from eukaryotes

(2008) Aude Martinez et al.   PROTEOMICS

Non-functional phosphorylations?

(2008) Gustav E. Lienhard   TRENDS IN BIOCHEMICAL SCIENCES