Global profiling of co- and post-translationally N-myristoylated proteomes in human cells

Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6

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The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes

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(2013) Dana Marcus et al.   MOLECULAR MEDICINE

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

(2013) Megan H. Wright et al.   Nature Chemistry

Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins

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Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite

(2013) B. Poulin et al.   Biology Open

Functional Interplay between Caspase Cleavage and Phosphorylation Sculpts the Apoptotic Proteome

(2012) Melissa M. Dix et al.   CELL

The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes

(2012) Alessia Indrieri et al.   EMBO Molecular Medicine

Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases

(2012) Maneka A. Perinpanayagam et al.   FASEB JOURNAL

The Mitochondrial Amidoxime-reducing Component (mARC1) Is a Novel Signal-anchored Protein of the Outer Mitochondrial Membrane

(2012) Julian M. Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation

(2012) Dominic Alibhai et al.   Journal of Biophotonics

Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression

(2012) S Braig et al.   ONCOGENE

Linking Crystallographic Model and Data Quality

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Bioorthogonal Chemical Reporters for Analyzing Protein Lipidation and Lipid Trafficking

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A fluorescence-based assay for N-myristoyltransferase activity

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Dynamic Monitoring of Newly Synthesized Proteomes: Up-Regulation of Myristoylated Protein Kinase A During Butyric Acid Induced Apoptosis

(2011) Kai Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Apoptosis Inhibitor ARC Promotes Breast Tumorigenesis, Metastasis, and Chemoresistance

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Bioorthogonal chemical tagging of protein cholesterylation in living cells

(2011) William P. Heal et al.   CHEMICAL COMMUNICATIONS

Chemical genetics

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A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension

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Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1

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The Batten disease gene CLN3 is required for the response to oxidative stress

(2011) Richard I. Tuxworth et al.   HUMAN MOLECULAR GENETICS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics

(2011) Tamar Geiger et al.   Nature Protocols

Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry

(2011) William P Heal et al.   Nature Protocols

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

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Post-translational myristoylation: Fat matters in cellular life and death

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Quantitative Proteomics Reveals Subset-Specific Viral Recognition in Dendritic Cells

(2010) Christian A. Luber et al.   IMMUNITY

Proteomic Analysis of Fatty-acylated Proteins in Mammalian Cells with Chemical Reporters RevealsS-Acylation of Histone H3 Variants

(2010) John P. Wilson et al.   MOLECULAR & CELLULAR PROTEOMICS

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Nestin expression in human tumors and tumor cell lines.

(2010) O. Krupkova_Jr et al.   NEOPLASMA

Mouse Cytoplasmic Dynein Intermediate Chains: Identification of New Isoforms, Alternative Splicing and Tissue Distribution of Transcripts

(2010) Anna Kuta et al.   PLoS One

A possible role of myristoylated alanine-rich C kinase substrate in endocytic pathway of Alzheimer’s disease

(2010) Rui Su et al.   Neuroscience Bulletin

xia2: an expert system for macromolecular crystallography data reduction

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N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

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Robust Fluorescent Detection of Protein Fatty-Acylation with Chemical Reporters

(2009) Guillaume Charron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

(2009) Viviana Cordeddu et al.   NATURE GENETICS

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

(2009) Jürgen Cox et al.   Nature Protocols

CRL4s: the CUL4-RING E3 ubiquitin ligases

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Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

(2008) Yusuke Sato et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

N-Myristoyl transferase-mediated protein labelling in vivo

(2008) William P. Heal et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef

(2007) K. E. Seaton et al.   JOURNAL OF GENERAL VIROLOGY