Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr−/− mice

Altered hepatic gene expression in nonalcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids

(2015) Bianca M. Arendt et al.   HEPATOLOGY

Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat–cholesterol–sugar diet model in mice

(2015) Michal Ganz et al.   Journal of Translational Medicine

Notch signaling as a novel regulator of metabolism

(2015) Pengpeng Bi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis

(2014) Joseph J Lee et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the WELCOME* study

(2014) Eleonora Scorletti et al.   HEPATOLOGY

Gut microbiota and liver disease

(2014) Amit Goel et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice

(2014) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

(2014) S. A. Joyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty Acid–Regulated Transcription Factors in the Liver

(2013) Donald B. Jump et al.   Annual Review of Nutrition

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

(2013) Takuji Ishimoto et al.   HEPATOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Docosahexaenoic Acid Attenuates Hepatic Inflammation, Oxidative Stress, and Fibrosis without Decreasing Hepatosteatosis in a Ldlr−/− Mouse Model of Western Diet-Induced Nonalcoholic Steatohepatitis

(2013) Christopher M. Depner et al.   JOURNAL OF NUTRITION

Fructose-induced stress signaling in the liver involves methylglyoxal

(2013) Yuren Wei et al.   Nutrition & Metabolism

SATgenɛ dietary model to implement diets of differing fat composition in prospectively genotyped groups (apoE) using commercially available foods

(2012) Stacey Lockyer et al.   BRITISH JOURNAL OF NUTRITION

Mechanisms of Simple Hepatic Steatosis

(2012) Scott C. Matherly et al.   Clinics in Liver Disease

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Non-alcoholic steatohepatitis: The role of oxidized low-density lipoproteins

(2012) Sofie M.A. Walenbergh et al.   JOURNAL OF HEPATOLOGY

Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepaticcis-vaccenic acid synthesis in diet-induced obese mice

(2012) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Menhaden Oil Decreases High-Fat Diet–Induced Markers of Hepatic Damage, Steatosis, Inflammation, and Fibrosis in Obese Ldlr−/− Mice

(2012) Christopher M. Depner et al.   JOURNAL OF NUTRITION

The role of dietary fatty acids in the pathology of metabolic syndrome

(2012) Ana Maria Lottenberg et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Low Docosahexaenoic Acid Content in Plasma Phospholipids is Associated with Increased Non-alcoholic Fatty Liver Disease in China

(2012) Ju-Sheng Zheng et al.   LIPIDS

Role of ceramides in nonalcoholic fatty liver disease

(2012) Mangesh Pagadala et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease

(2012) Matteo Nicola Dario Di Minno   WORLD JOURNAL OF GASTROENTEROLOGY

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

(2011) Michael Charlton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial

(2011) V. Nobili et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes

(2011) J.M. Petit et al.   CLINICAL NUTRITION

A High-Cholesterol Diet Exacerbates Liver Fibrosis in Mice via Accumulation of Free Cholesterol in Hepatic Stellate Cells

(2011) Toshiaki Teratani et al.   GASTROENTEROLOGY

Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase

(2011) David A. Brenner et al.   HEPATOLOGY RESEARCH

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence

(2011) Shira Zelber-Sagi   WORLD JOURNAL OF GASTROENTEROLOGY

Does vitamin E cure nonalcoholic steatohepatitis?

(2011) Luigi E Adinolfi et al.   Expert Review of Gastroenterology & Hepatology

Current status of novel antifibrotic therapies in patients with chronic liver disease

(2011) Michal Cohen-Naftaly et al.   Therapeutic Advances in Gastroenterology

The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver disease

(2010) Haim Shapiro et al.   CLINICAL NUTRITION

Intake of Added Sugars and Selected Nutrients in the United States, National Health and Nutrition Examination Survey (NHANES) 2003—2006

(2010) Bernadette P. Marriott et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Epidemiology of Non-Alcoholic Fatty Liver Disease

(2010) Stefano Bellentani et al.   DIGESTIVE DISEASES

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

(2010) Kristiaan Wouters et al.   FEBS LETTERS

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Epidemiology of the metabolic syndrome in the USA

(2010) Arthur J McCULLOUGH   Journal of Digestive Diseases

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice

(2010) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation

(2010) Fabienne Laugerette et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Changes in Intakes of Total and Added Sugar and their Contribution to Energy Intake in the U.S.

(2010) Ock K. Chun et al.   Nutrients

Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome

(2009) C. H. KIM et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up

(2009) Cecilia Söderberg et al.   HEPATOLOGY

Effectiveness of Combined Statin Plus Omega-3 Fatty Acid Therapy for Mixed Dyslipidemia

(2008) Philip Barter et al.   AMERICAN JOURNAL OF CARDIOLOGY

Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent

(2008) Laura H. Tetri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Fructose-induced structural and functional modifications of hemoglobin: Implication for oxidative stress in diabetes mellitus

(2008) Tania Bose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Competitive inhibition of leptin signaling results in amelioration of liver fibrosis through modulation of stellate cell function

(2008) Eran Elinav et al.   HEPATOLOGY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Nutritional investigation of non-obese patients with non-alcoholic fatty liver disease: The significance of dietary cholesterol

(2008) Kenichiro Yasutake et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

(2008) Fabio Marra et al.   TRENDS IN MOLECULAR MEDICINE