Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

(2014) Kuok Teong Ong et al.   JOURNAL OF LIPID RESEARCH

Fatty Acid–Regulated Transcription Factors in the Liver

(2013) Donald B. Jump et al.   Annual Review of Nutrition

High-Fat Diet-Mediated Lipotoxicity and Insulin Resistance Is Related to Impaired Lipase Expression in Mouse Skeletal Muscle

(2013) Pierre-Marie Badin et al.   ENDOCRINOLOGY

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

(2013) Pooja Jha et al.   HEPATOLOGY

Docosahexaenoic Acid Attenuates Hepatic Inflammation, Oxidative Stress, and Fibrosis without Decreasing Hepatosteatosis in a Ldlr−/− Mouse Model of Western Diet-Induced Nonalcoholic Steatohepatitis

(2013) Christopher M. Depner et al.   JOURNAL OF NUTRITION

A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

(2013) Christopher M. Depner et al.   PLoS One

Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation

(2013) Heriberto Rodríguez-Hernández et al.   International Journal of Endocrinology

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat-Fed Mice but Not in Leptin-Deficient Mice

(2012) S. Boudina et al.   DIABETES

Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet

(2012) Byounghoon Hwang et al.   FEBS Journal

Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling

(2012) Sascha Obrowsky et al.   JOURNAL OF LIPID RESEARCH

Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepaticcis-vaccenic acid synthesis in diet-induced obese mice

(2012) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Menhaden Oil Decreases High-Fat Diet–Induced Markers of Hepatic Damage, Steatosis, Inflammation, and Fibrosis in Obese Ldlr−/− Mice

(2012) Christopher M. Depner et al.   JOURNAL OF NUTRITION

Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice

(2012) Xin Guo et al.   PLoS One

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

(2011) Mark A. Cole et al.   BASIC RESEARCH IN CARDIOLOGY

Liver triacylglycerol lipases

(2011) Ariel D. Quiroga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes

(2011) J.M. Petit et al.   CLINICAL NUTRITION

Feed restriction up-regulates uncoupling protein 3 (UCP3) gene expression in heart and red muscle tissues of gilthead sea bream (Sparus aurata L.)

(2011) Azucena Bermejo-Nogales et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage

(2011) C V Musa et al.   INTERNATIONAL JOURNAL OF OBESITY

Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)

(2011) Ramy R. Attia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet

(2011) Takashi Uebanso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes

(2011) Zhi-Hong Yang et al.   Lipids in Health and Disease

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

(2011) Guenter Haemmerle et al.   NATURE MEDICINE

Viscous Dietary Fiber Reduces Adiposity and Plasma Leptin and Increases Muscle Expression of Fat Oxidation Genes in Rats

(2011) Ajmila Islam et al.   Obesity

Interactions between the consumption of a high-fat diet and fasting in the regulation of fatty acid oxidation enzyme gene expression: an evaluation of potential mechanisms

(2010) Bruce C. Frier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation

(2010) Donald B. Jump et al.   BIOCHEMICAL PHARMACOLOGY

Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling

(2010) Sara Violante et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis

(2010) J. Huang et al.   DIABETES

Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

(2010) P. Chakrabarti et al.   DIABETES

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

(2010) Kuok Teong Ong et al.   HEPATOLOGY

Mitochondrial fatty acid oxidation disorders: pathophysiological studies in mouse models

(2010) Ute Spiekerkoetter et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice

(2010) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species

(2010) Christopher D. Green et al.   JOURNAL OF LIPID RESEARCH

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways

(2010) Rosalba Senese et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

(2010) Y. Ohno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoxO1 Controls Insulin-dependent Adipose Triglyceride Lipase (ATGL) Expression and Lipolysis in Adipocytes

(2009) Partha Chakrabarti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice

(2008) Nam Ho Jeoung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training

(2008) Thomas J. Alsted et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Recent advances in nonalcholic fatty liver disease

(2008) Victoria Greenfield et al.   CURRENT OPINION IN GASTROENTEROLOGY

Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

(2008) Brendan N. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

(2008) Hideaki Miyoshi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

(2008) Rudolf Zechner et al.   JOURNAL OF LIPID RESEARCH

Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition

(2008) Yun Wang et al.   JOURNAL OF LIPID RESEARCH

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

(2008) Young-Ah Moon et al.   JOURNAL OF LIPID RESEARCH

Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling

(2008) Christine T. Ferrara et al.   PLoS Genetics