Current status of novel antifibrotic therapies in patients with chronic liver disease

Brief Communication: The Relationship of Regression of Cirrhosis to Outcome in Chronic Hepatitis C

(2013) Vincent Mallet et al.   ANNALS OF INTERNAL MEDICINE

A New Combination of Blood Test and Fibroscan for Accurate Non-Invasive Diagnosis of Liver Fibrosis Stages in Chronic Hepatitis C

(2011) Jérôme Boursier et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C

(2011) Julien Vergniol et al.   GASTROENTEROLOGY

Oltipraz therapy in patients with liver fibrosis or cirrhosis: a randomized, double-blind, placebo-controlled phase II trial

(2011) Sang Geon Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Circulating markers of liver fibrosis progression

(2010) Peter Jarčuška et al.   CLINICA CHIMICA ACTA

Complication Rate of Percutaneous Liver Biopsies Among Persons With Advanced Chronic Liver Disease in the HALT-C Trial

(2010) Leonard B. Seeff et al.   Clinical Gastroenterology and Hepatology

The Effects of Angiotensin Blocking Agents on the Progression of Liver Fibrosis in the HALT-C Trial Cohort

(2010) Barham K. Abu Dayyeh et al.   DIGESTIVE DISEASES AND SCIENCES

Pentoxifylline Does Not Decrease Short-term Mortality but Does Reduce Complications in Patients With Advanced Cirrhosis

(2010) Didier Lebrec et al.   GASTROENTEROLOGY

Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

(2010) David Scholten et al.   GASTROENTEROLOGY

Liver X Receptor Signaling Is a Determinant of Stellate Cell Activation and Susceptibility to Fibrotic Liver Disease

(2010) Simon W. Beaven et al.   GASTROENTEROLOGY

Institute of Medicine recommendations for the prevention and control of hepatitis B and C

(2010) Abigail E. Mitchell et al.   HEPATOLOGY

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

(2010) Christoph Roderburg et al.   HEPATOLOGY

Leptin Promotes the Myofibroblastic Phenotype in Hepatic Stellate Cells by Activating the Hedgehog Pathway

(2010) Steve S. Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caffeine, a drug for all seasons

(2010) Bruce N. Cronstein   JOURNAL OF HEPATOLOGY

Adenosine: Tipping the balance towards hepatic steatosis and fibrosis

(2010) Simon C. Robson et al.   JOURNAL OF HEPATOLOGY

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

(2010) Yan Wang et al.   JOURNAL OF HEPATOLOGY

S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats

(2010) Rafael Vercelino et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Transcriptional regulation of hepatic stellate cells

(2009) Jelena Mann et al.   ADVANCED DRUG DELIVERY REVIEWS

Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

(2009) Jordi Colmenero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis

(2009) Fiona Oakley et al.   GASTROENTEROLOGY

Farglitazar Lacks Antifibrotic Activity in Patients With Chronic Hepatitis C Infection

(2009) John McHutchison et al.   GASTROENTEROLOGY

Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression

(2009) Gary L. Davis et al.   GASTROENTEROLOGY

Toll-like receptors as targets in chronic liver diseases

(2009) A Mencin et al.   GUT

Increased caffeine consumption is associated with reduced hepatic fibrosis

(2009) Apurva A. Modi et al.   HEPATOLOGY

Bone marrow transplantation demonstrates medullar origin of CD34+ fibrocytes and ameliorates hepatic fibrosis in Abcb4−/− mice

(2009) Martin Roderfeld et al.   HEPATOLOGY

Liver stiffness identifies two different patterns of fibrosis progression in patients with hepatitis C virus recurrence after liver transplantation

(2009) José A. Carrión et al.   HEPATOLOGY

Portal fibroblasts: Underappreciated mediators of biliary fibrosis

(2009) Jonathan A. Dranoff et al.   HEPATOLOGY

Epithelial-to-mesenchymal transitions in the liver

(2009) Steve S. Choi et al.   HEPATOLOGY

Prognostic value of Ishak fibrosis stage: Findings from the hepatitis C antiviral long-term treatment against cirrhosis trial

(2009) James E. Everhart et al.   HEPATOLOGY

Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C

(2009) Neal D. Freedman et al.   HEPATOLOGY

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

(2009) Kojiro Taura et al.   HEPATOLOGY

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

(2009) Montserrat Moreno et al.   HEPATOLOGY

Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases

(2009) B. Gao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection

(2009) S. A. Gonzalez et al.   JOURNAL OF VIRAL HEPATITIS

The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C

(2009) Kathleen E. Corey et al.   LIVER INTERNATIONAL

Angiotensin II antagonists in patients with recurrent hepatitis C virus infection after liver transplantation

(2009) Evangelos Cholongitas et al.   LIVER INTERNATIONAL

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis

(2009) Vanessa Deveaux et al.   PLoS One

Liver Fibrosis in Viral Hepatitis: Noninvasive Assessment with Acoustic Radiation Force Impulse Imaging versus Transient Elastography

(2009) Mireen Friedrich-Rust et al.   RADIOLOGY

Advances in antifibrotic therapy

(2009) Zahra Ghiassi-Nejad et al.   Expert Review of Gastroenterology & Hepatology

A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells

(2008) Bernd Schnabl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Liver fibrosis

(2008) Karen Wallace et al.   BIOCHEMICAL JOURNAL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Current and Future Anti-Fibrotic Therapies for Chronic Liver Disease

(2008) Don C. Rockey   Clinics in Liver Disease

Liver transplantation: an update 2008

(2008) Adnan Said et al.   CURRENT OPINION IN GASTROENTEROLOGY

A Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial of Etanercept in the Treatment of Alcoholic Hepatitis

(2008) Nicholas C. Boetticher et al.   GASTROENTEROLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of toll-like receptor 4 to hepatic stellate cell responses

(2008) Jinsheng Guo et al.   HEPATOLOGY

Hepatoprotective Effect of Infliximab, an Anti-TNF-α Agent, on Carbon Tetrachloride-Induced Hepatic Fibrosis

(2008) Ibrahim Halil Bahcecioglu et al.   INFLAMMATION

Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis

(2008) Haruko Sugino et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways

(2008) Olav A. Gressner et al.   JOURNAL OF HEPATOLOGY

Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: Therapeutic implications for hepatitis C

(2008) Inga Wedemeyer et al.   JOURNAL OF HEPATOLOGY

Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats

(2008) Olga Ohayon et al.   LABORATORY INVESTIGATION

Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

(2008) Adrian M. Di Bisceglie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Curcumin: potential for hepatic fibrosis therapy?

(2007) M A O'Connell et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo

(2007) S De Minicis et al.   GUT