Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepaticcis-vaccenic acid synthesis in diet-induced obese mice
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Title
Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepaticcis-vaccenic acid synthesis in diet-induced obese mice
Authors
Keywords
-
Journal
JOURNAL OF LIPID RESEARCH
Volume 54, Issue 1, Pages 71-84
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-10-25
DOI
10.1194/jlr.m028787
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- (2010) Jian Gong et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
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- mTOR and cancer: many loops in one pathway
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