Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease

Control of IFN- A by CD73: Implications for Mucosal Inflammation

(2014) N. A. Louis et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Hypoxia signaling during intestinal ischemia and inflammation

(2012) Almut Grenz et al.   Current Opinion in Critical Care

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice

(2012) Almut Grenz et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

(2012) Li Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Adora2b Adenosine Receptor Signaling Protects during Acute Kidney Injury via Inhibition of Neutrophil-Dependent TNF-α Release

(2012) Almut Grenz et al.   JOURNAL OF IMMUNOLOGY

Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury

(2012) M Koeppen et al.   Mucosal Immunology

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia

(2012) Tobias Eckle et al.   NATURE MEDICINE

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

(2012) E. T. Clambey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery

(2011) Sean P. Colgan et al.   Annual Review of Physiology

Adenosine and ATP Receptors in the Brain

(2011) Geoffrey Burnstock et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis

(2011) Carol M Aherne et al.   GUT

Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor

(2011) Melanie L. Hart et al.   JOURNAL OF IMMUNOLOGY

Adenosine Generation and Signaling during Acute Kidney Injury

(2011) J. D. Bauerle et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Partial Netrin-1 Deficiency Aggravates Acute Kidney Injury

(2011) Almut Grenz et al.   PLoS One

Netrin-1 Dampens Pulmonary Inflammation during Acute Lung Injury

(2010) Valbona Mirakaj et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The resurgence of A2B adenosine receptor signaling

(2010) Carol M. Aherne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Selective induction of endothelial P2Y6 nucleotide receptor promotes vascular inflammation

(2010) A.-K. Riegel et al.   BLOOD

Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function

(2010) Murtaza M. Tambuwala et al.   GASTROENTEROLOGY

The cellular response to hypoxia: tuning the system with microRNAs

(2010) Joseph Loscalzo   JOURNAL OF CLINICAL INVESTIGATION

SP1-Dependent Induction of CD39 Facilitates Hepatic Ischemic Preconditioning

(2010) M. L. Hart et al.   JOURNAL OF IMMUNOLOGY

Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

(2010) U. Schingnitz et al.   JOURNAL OF IMMUNOLOGY

Netrin-1 Signaling Dampens Inflammatory Peritonitis

(2010) V. Mirakaj et al.   JOURNAL OF IMMUNOLOGY

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Adenosine: An Old Drug Newly Discovered

(2009) Holger K. Eltzschig   ANESTHESIOLOGY

Oxygen Sensors at the Crossroad of Metabolism

(2009) Julián Aragonés et al.   Cell Metabolism

Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation

(2009) Holger K Eltzschig et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cutting Edge: A2B Adenosine Receptor Signaling Provides Potent Protection during Intestinal Ischemia/Reperfusion Injury

(2009) M. L. Hart et al.   JOURNAL OF IMMUNOLOGY

Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis

(2009) J.-S. Frick et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia

(2009) Peter Rosenberger et al.   NATURE IMMUNOLOGY

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Role of Extracellular Adenosine in Acute Lung Injury

(2009) Tobias Eckle et al.   PHYSIOLOGY

Adenosine A2A receptor is a unique angiogenic target of HIF-2  in pulmonary endothelial cells

(2009) A. Ahmad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease

(2009) D. J. Friedman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of a hanging-weight system for liver ischemic preconditioning in mice

(2008) Melanie L. Hart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Direct Treatment of Mouse or Human Blood With Soluble 5′-Nucleotidase Inhibits Platelet Aggregation

(2008) Melanie L. Hart et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak

(2008) J. C. Morote-Garcia et al.   BLOOD

Central role of Sp1-regulated CD39 in hypoxia/ischemia protection

(2008) H. K. Eltzschig et al.   BLOOD

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury

(2008) Melanie L. Hart et al.   FASEB JOURNAL

Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs

(2008) Jörg Reutershan et al.   FASEB JOURNAL

Hypoxia-Independent Activation of HIF-1 by Enterobacteriaceae and Their Siderophores

(2008) Hanna Hartmann et al.   GASTROENTEROLOGY

Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia

(2008) Julio C. Morote–Garcia et al.   GASTROENTEROLOGY

Emerging role of adipose tissue hypoxia in obesity and insulin resistance

(2008) J Ye   INTERNATIONAL JOURNAL OF OBESITY

Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation

(2008) Cormac T. Taylor   JOURNAL OF PHYSIOLOGY-LONDON

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia

(2008) Marion Faigle et al.   PLoS One

Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection

(2008) Helene A. Haeberle et al.   PLoS One

Neutrophils as Sources of Extracellular Nucleotides: Functional Consequences at the Vascular Interface

(2008) Holger K. Eltzschig et al.   TRENDS IN CARDIOVASCULAR MEDICINE

The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia

(2008) Almut Grenz et al.   PLOS MEDICINE

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY