Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling

(2013) Marja Driessen et al.   ARCHIVES OF TOXICOLOGY

Real-time imaging and genetic dissection of host-microbe interactions in zebrafish

(2013) Annemarie H. Meijer et al.   CELLULAR MICROBIOLOGY

Adipose Dipeptidyl Peptidase-4 and Obesity: Correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

(2013) H. Sell et al.   DIABETES CARE

The emerging use of zebrafish to model metabolic disease

(2013) A. Seth et al.   Disease Models & Mechanisms

Hepatocyte-specificPtpn6deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: Potential role of PPARγ

(2013) Elaine Xu et al.   HEPATOLOGY

Deficiency in Hematopoietic Phosphatase Ptpn6/Shp1 Hyperactivates the Innate Immune System and Impairs Control of Bacterial Infections in Zebrafish Embryos

(2013) Z. Kanwal et al.   JOURNAL OF IMMUNOLOGY

Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance

(2013) Elaine Xu et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance

(2012) E. Xu et al.   DIABETES

Hooked! Modeling human disease in zebrafish

(2012) Cristina Santoriello et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Zebrafish Models for Cancer

(2011) Shu Liu et al.   Annual Review of Pathology-Mechanisms of Disease

Zebrafish embryos and larvae: A new generation of disease models and drug screens

(2011) Shaukat Ali et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Host-Pathogen Interactions Made Transparent with the Zebrafish Model

(2011) Annemarie H. Meijer et al.   CURRENT DRUG TARGETS

Hypermethylation of Hepatic Glucokinase and L-Type Pyruvate Kinase Promoters in High-Fat Diet–Induced Obese Rats

(2011) Minghong Jiang et al.   ENDOCRINOLOGY

Refeeding after Fasting Elicits Insulin-Dependent Regulation of Per2 and Rev-erbα with Shifts in the Liver Clock

(2011) Yu Tahara et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

(2011) Susumu Seino et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish

(2010) Agata Jurczyk et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels

(2009) Ulrike Lorenz   IMMUNOLOGICAL REVIEWS

Current views on type 2 diabetes

(2009) Yi Lin et al.   JOURNAL OF ENDOCRINOLOGY

Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution

(2009) Marnix Gorissen et al.   JOURNAL OF ENDOCRINOLOGY

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

(2009) V. T. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Resistance and Hyperinsulinemia: Is hyperinsulinemia the cart or the horse?

(2008) M. H. Shanik et al.   DIABETES CARE

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1

(2008) Huazhang An et al.   NATURE IMMUNOLOGY

Correction for Bissell and Inman et al., Reprogramming stem cells is a microenvironmental task

(2008)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA