Zebrafish embryos and larvae: A new generation of disease models and drug screens

Use of a High-Throughput Screening Approach Coupled with In Vivo Zebrafish Embryo Screening To Develop Hazard Ranking for Engineered Nanomaterials

(2011) Saji George et al.   ACS Nano

Patterns of avoidance behaviours in the light/dark preference test in young juvenile zebrafish: A pharmacological study

(2011) Peter J. Steenbergen et al.   BEHAVIOURAL BRAIN RESEARCH

Labelling cell structures and tracking cell lineage in zebrafish using SNAP-tag

(2011) Cláudia Campos et al.   DEVELOPMENTAL DYNAMICS

A High-Throughput Screen for Tuberculosis Progression

(2011) Ralph Carvalho et al.   PLoS One

Large-Scale Analysis of Acute Ethanol Exposure in Zebrafish Development: A Critical Time Window and Resilience

(2011) Shaukat Ali et al.   PLoS One

Pharmacological analysis of zebrafish (Danio rerio) scototaxis

(2011) Caio Maximino et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish

(2011) Caroline Gray et al.   THROMBOSIS AND HAEMOSTASIS

Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies

(2011) Sanne A.B. Hermsen et al.   TOXICOLOGY IN VITRO

Zebrafish Preference for Light or Dark Is Dependent on Ambient Light Levels and Olfactory Stimulation

(2011) Jessica F. Stephenson et al.   Zebrafish

Zebrafish: An in vivo model for the study of neurological diseases

(2011) Jonathan Best   Neuropsychiatric Disease and Treatment

Translating rodent behavioral repertoire to zebrafish (Danio rerio): Relevance for stress research

(2010) Danielle L. Champagne et al.   BEHAVIOURAL BRAIN RESEARCH

Parametric analyses of anxiety in zebrafish scototaxis

(2010) Caio Maximino et al.   BEHAVIOURAL BRAIN RESEARCH

Characterization of behavioral and endocrine effects of LSD on zebrafish

(2010) Leah Grossman et al.   BEHAVIOURAL BRAIN RESEARCH

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Zebrafish: A tool for chemical screens

(2010) Michael Tsang   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish

(2010) F. Ellett et al.   BLOOD

Phenotypic analysis of images of zebrafish treated with Alzheimer's gamma-secretase inhibitors

(2010) Dilyara Arslanova et al.   BMC BIOTECHNOLOGY

Separation and aquatic toxicity of enantiomers of the organophosphorus insecticide O-ethyl O-4-nitrophenyl phenylphosphonothioate (EPN)

(2010) Jianqiang Sun et al.   CHEMOSPHERE

Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen

(2010) David S. Peal et al.   CIRCULATION

Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1frc/frc mice

(2010) B. K. Y. Wong et al.   GENES BRAIN AND BEHAVIOR

Zebrafish models of collagen VI-related myopathies

(2010) W.R. Telfer et al.   HUMAN MOLECULAR GENETICS

In vivo analysis of gut function and disease changes in a zebrafish larvae model of inflammatory bowel disease

(2010) Angeleen Fleming et al.   INFLAMMATORY BOWEL DISEASES

Ccm1 Regulates Microvascular Morphogenesis during Angiogenesis

(2010) Huiling Liu et al.   JOURNAL OF VASCULAR RESEARCH

Big ideas for small brains: what can psychiatry learn from worms, flies, bees and fish?

(2010) T Burne et al.   MOLECULAR PSYCHIATRY

High-Throughput Behavioral Screens: the First Step towards Finding Genes Involved in Vertebrate Brain Function Using Zebrafish

(2010) Robert Gerlai   MOLECULES

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

(2010) David Kokel et al.   Nature Chemical Biology

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

(2010) Joachim Goedhart et al.   NATURE METHODS

Fast, high-contrast imaging of animal development with scanned light sheet–based structured-illumination microscopy

(2010) Philipp J Keller et al.   NATURE METHODS

Measuring behavioral and endocrine responses to novelty stress in adult zebrafish

(2010) Jonathan Cachat et al.   Nature Protocols

Scototaxis as anxiety-like behavior in fish

(2010) Caio Maximino et al.   Nature Protocols

Cross-species assessments of motor and exploratory behavior related to bipolar disorder

(2010) Brook L. Henry et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Locomotor activity in zebrafish embryos: A new method to assess developmental neurotoxicity

(2010) Ingrid W.T. Selderslaghs et al.   NEUROTOXICOLOGY AND TERATOLOGY

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

Cardiac conduction is required to preserve cardiac chamber morphology

(2010) N. C. Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of the zebrafish model in stress research

(2010) Peter J. Steenbergen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models

(2010) Adam Stewart et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

(2010) J. Rihel et al.   SCIENCE

An Information-Rich Alternative, Chemicals Testing Strategy Using a High Definition Toxicogenomics and Zebrafish (Danio rerio) Embryos

(2010) Ashley D. Sawle et al.   TOXICOLOGICAL SCIENCES

Evaluation of cytotoxicity, genotoxicity and teratogenicity of marine sediments from Qingdao coastal areas using in vitro fish cell assay, comet assay and zebrafish embryo test

(2010) Fan Yang et al.   TOXICOLOGY IN VITRO

Long-Term Behavioral Changes in Response to Early Developmental Exposure to Ethanol in Zebrafish

(2009) Yohaan Fernandes et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

A Reverse-Translational Study of Dysfunctional Exploration in Psychiatric Disorders

(2009) William Perry et al.   ARCHIVES OF GENERAL PSYCHIATRY

Zebrafish antipredatory responses: A future for translational research?

(2009) Robert Gerlai   BEHAVIOURAL BRAIN RESEARCH

Modeling withdrawal syndrome in zebrafish

(2009) Jonathan Cachat et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral measures of anxiety in zebrafish (Danio rerio)

(2009) R.E. Blaser et al.   BEHAVIOURAL BRAIN RESEARCH

Biophysical properties of zebrafish ether-à-go-go related gene potassium channels

(2009) Eberhard P. Scholz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Rapidly Maturing Far-Red Derivative of DsRed-Express2 for Whole-Cell Labeling

(2009) Rita L. Strack et al.   BIOCHEMISTRY

Single-Molecule Microscopy Reveals Membrane Microdomain Organization of Cells in a Living Vertebrate

(2009) Marcel J.M. Schaaf et al.   BIOPHYSICAL JOURNAL

Deciphering the role of Shh signaling in axial defects produced by ethanol exposure

(2009) Evyn J. Loucks et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A novel zebrafish jak2aV581F model shared features of human JAK2V617F polycythemia vera

(2009) Alvin C.H. Ma et al.   EXPERIMENTAL HEMATOLOGY

Using zebrafish to assess the impact of drugs on neural development and function

(2009) Su Guo   Expert Opinion on Drug Discovery

Zebrafish development and regeneration: new tools for biomedical research

(2009) Sebastiaan A. Brittijn et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

How to make a teleost adenohypophysis: Molecular pathways of pituitary development in zebrafish

(2009) Hans-Martin Pogoda et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Acute neuroactive drug exposures alter locomotor activity in larval zebrafish

(2009) T.D. Irons et al.   NEUROTOXICOLOGY AND TERATOLOGY

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals

(2009) Lixin Yang et al.   REPRODUCTIVE TOXICOLOGY

Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo

(2009) Ingrid W.T. Selderslaghs et al.   REPRODUCTIVE TOXICOLOGY

A Student Team in a University of Michigan Biomedical Engineering Design Course Constructs a Microfluidic Bioreactor for Studies of Zebrafish Development

(2009) Yu-Chi Shen et al.   Zebrafish

Shuttle box learning in zebrafish (Danio rerio)

(2008) Shalini Pather et al.   BEHAVIOURAL BRAIN RESEARCH

Zebrafish: an emerging technology forin vivopharmacological assessment to identify potential safety liabilities in early drug discovery

(2008) T P Barros et al.   BRITISH JOURNAL OF PHARMACOLOGY

Deficient Zebrafish Ether-à-Go-Go –Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants

(2008) David Hassel et al.   CIRCULATION

A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle

(2008) K. Dutton et al.   Disease Models & Mechanisms

Zebrafish: a predictive model for assessing drug-induced toxicity

(2008) Patricia McGrath et al.   DRUG DISCOVERY TODAY

montalcino, A zebrafish model for variegate porphyria

(2008) Kimberly A. Dooley et al.   EXPERIMENTAL HEMATOLOGY

In vivo long-term continuous observation of gene expression in zebrafish embryo nerve systems by using harmonic generation microscopy and morphant technology

(2008) Cho-Shuen Hsieh et al.   JOURNAL OF BIOMEDICAL OPTICS

Three-dimensional (3D) backward and forward second harmonic generation (SHG) microscopy of biological tissues

(2008) Paolo Bianchini et al.   Journal of Biophotonics

The function of wall-following behaviors in the Mexican blind cavefish and a sighted relative, the Mexican tetra (Astyanax)

(2008) Saurabh Sharma et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY

Zebrafish as a new animal model for movement disorders

(2008) Laura Flinn et al.   JOURNAL OF NEUROCHEMISTRY

Locomotion in larval zebrafish: Influence of time of day, lighting and ethanol

(2008) R.C. MacPhail et al.   NEUROTOXICOLOGY

Zebrafish as a Developmental Model Organism for Pediatric Research

(2008) Matthew B Veldman et al.   PEDIATRIC RESEARCH

Gender differences in zebrafish responses to cocaine withdrawal

(2008) Marcos A. López Patiño et al.   PHYSIOLOGY & BEHAVIOR

The link between childhood trauma and depression: Insights from HPA axis studies in humans

(2008) Christine Heim et al.   PSYCHONEUROENDOCRINOLOGY

The effects of ethanol on CNS development in the chick embryo

(2008) Seamus Giles et al.   REPRODUCTIVE TOXICOLOGY

Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy

(2008) P. J. Keller et al.   SCIENCE

Fundamental aspects of the impact of glucocorticoids on the (immature) brain

(2008) Danielle L. Champagne et al.   Seminars in Fetal & Neonatal Medicine

Development of a New Screening Assay to Identify Proteratogenic Substances using Zebrafish Danio rerio Embryo Combined with an Exogenous Mammalian Metabolic Activation System (mDarT)

(2008) François Busquet et al.   TOXICOLOGICAL SCIENCES

Zebrafish assays as early safety pharmacology screens: Paradigm shift or red herring?

(2008) William S. Redfern et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Validation of the use of zebrafish larvae in visual safety assessment

(2008) F.M. Richards et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery

(2008) Stéphane Berghmans et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs

(2008) Matthew J. Winter et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

(2008) Neil C Chi et al.   PLOS BIOLOGY

Discovery of a Functional Glucocorticoid Receptor β-Isoform in Zebrafish

(2007) Marcel J. M. Schaaf et al.   ENDOCRINOLOGY

Fast screening of paramagnetic molecules in zebrafish embryos by MRI

(2007) Laurence Canaple et al.   NMR IN BIOMEDICINE

Anxiogenic effects of cocaine withdrawal in zebrafish

(2007) Marcos A. López-Patiño et al.   PHYSIOLOGY & BEHAVIOR

Evaluation of zebrafish embryos as a model for assessing inhibition of hERG

(2007) S.W. Mittelstadt et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS