Phosphorylation of IRS proteins, insulin action, and insulin resistance

siRNA-Mediated Reduction of Inhibitor of Nuclear Factor- B Kinase Prevents Tumor Necrosis Factor- -Induced Insulin Resistance in Human Skeletal Muscle

(2008) R. L. Austin et al.   DIABETES

Muscle-Specific IRS-1 Ser->Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

(2008) K. Morino et al.   DIABETES

mTOR Inhibition by Rapamycin Prevents  -Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

(2008) M. Fraenkel et al.   DIABETES

Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1, -3, and -4 But Not -2: Isoform Specific Determinants of Specificity in Insulin Signaling

(2008) Sihoon Lee et al.   ENDOCRINOLOGY

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2

(2008) Jinhua Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SIK2 Can be Activated by Deprivation of Nutrition and It Inhibits Expression of Lipogenic Genes in Adipocytes

(2008) Jing Du et al.   Obesity

Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling

(2007) Hadar Sharfi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM