In-vitro blood–brain barrier modeling: A review of modern and fast-advancing technologies

3D-printed gelatin scaffolds of differing pore geometry modulate hepatocyte function and gene expression

(2018) Phillip L. Lewis et al.   Acta Biomaterialia

Fabricating smooth PDMS microfluidic channels from low-resolution 3D printed molds using an omniphobic lubricant-infused coating

(2018) Martin Villegas et al.   ANALYTICA CHIMICA ACTA

Stem cells and combination therapy for the treatment of traumatic brain injury

(2018) AmiraSan Dekmak et al.   BEHAVIOURAL BRAIN RESEARCH

3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues

(2018) Lobat Tayebi et al.   MATERIALS LETTERS

3D printed microfluidics and microelectronics

(2018) Ryan D. Sochol et al.   MICROELECTRONIC ENGINEERING

3D printed microfluidic device with integrated optical sensing for particle analysis

(2018) S.M. Hampson et al.   SENSORS AND ACTUATORS B-CHEMICAL

Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells

(2017) Chaitali Ghosh et al.   EPILEPSIA

Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality

(2017) Ronak Patel et al.   JOURNAL OF NEUROCHEMISTRY

Simplified fabrication of integrated microfluidic devices using fused deposition modeling 3D printing

(2017) Gabriel Gaal et al.   SENSORS AND ACTUATORS B-CHEMICAL

Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury

(2017) Anwarul Hasan et al.   Frontiers in Neurology

Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

(2017) Shikha Prasad et al.   Redox Biology

Remodeling the blood–brain barrier microenvironment by natural products for brain tumor therapy

(2017) Xiao Zhao et al.   Acta Pharmaceutica Sinica B

Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier

(2017) Xiaohe Tian et al.   Scientific Reports

Immortalized endothelial cell lines for in vitro blood–brain barrier models: A systematic review

(2016) Nurul Adhwa Rahman et al.   BRAIN RESEARCH

New experimental models of the blood-brain barrier for CNS drug discovery

(2016) Mohammad A. Kaisar et al.   Expert Opinion on Drug Discovery

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

(2016) Hans C Helms et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Stem Cell-Based Human Blood–Brain Barrier Models for Drug Discovery and Delivery

(2016) S. Aday et al.   TRENDS IN BIOTECHNOLOGY

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

(2015) Jacquelyn A. Brown et al.   Biomicrofluidics

Conductive 3D microstructures by direct 3D printing of polymer/carbon nanotube nanocomposites via liquid deposition modeling

(2015) Giovanni Postiglione et al.   COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING

3D printed microfluidics for biological applications

(2015) Chee Meng Benjamin Ho et al.   LAB ON A CHIP

Inkjet printing for biosensor fabrication: combining chemistry and technology for advanced manufacturing

(2015) Jia Li et al.   LAB ON A CHIP

Anatomy and physiology of the blood–brain barrier

(2015) Yonatan Serlin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

3D printed molds for non-planar PDMS microfluidic channels

(2015) Yongha Hwang et al.   SENSORS AND ACTUATORS A-PHYSICAL

3D Printed Unibody Lab-on-a-Chip: Features Survey and Check-Valves Integration

(2015) Germán Comina et al.   Micromachines

Bench-to-Bedside and Bedside Back to the Bench; Seeking a Better Understanding of the Acute Pathophysiological Process in Severe Traumatic Brain Injury

(2015) Denes V. Agoston   Frontiers in Neurology

Fiber Encapsulation Additive Manufacturing: An Enabling Technology for 3D Printing of Electromechanical Devices and Robotic Components

(2015) Matt Saari et al.   3D Printing and Additive Manufacturing

3D Optical Printing of Piezoelectric Nanoparticle–Polymer Composite Materials

(2014) Kanguk Kim et al.   ACS Nano

Enhancement of Blood-Brain Barrier Permeability and Reduction of Tight Junction Protein Expression Are Modulated by Chemokines/Cytokines Induced by Rabies Virus Infection

(2014) Q. Chai et al.   JOURNAL OF VIROLOGY

Mechanical properties of components fabricated with open-source 3-D printers under realistic environmental conditions

(2014) B.M. Tymrak et al.   MATERIALS & DESIGN

In Vitro Models of the Blood–Brain Barrier for the Study of Drug Delivery to the Brain

(2014) Imola Wilhelm et al.   MOLECULAR PHARMACEUTICS

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

Active origami by 4D printing

(2014) Qi Ge et al.   Smart Materials and Structures

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling

(2014) Xiaojun Lian et al.   Stem Cell Reports

Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound

(2013) Jessica F. Jordão et al.   EXPERIMENTAL NEUROLOGY

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Design and additive manufacture for flow chemistry

(2013) Andrew J. Capel et al.   LAB ON A CHIP

From Blood to the Brain: Can Systemically Transplanted Mesenchymal Stem Cells Cross the Blood-Brain Barrier?

(2013) Linan Liu et al.   Stem Cells International

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering

(2012) Thomas Billiet et al.   BIOMATERIALS

Reliable permeability assay system in a microfluidic device mimicking cerebral vasculatures

(2012) Ju Hun Yeon et al.   BIOMEDICAL MICRODEVICES

On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices

(2012) Mandy Brigitte Esch et al.   BIOMEDICAL MICRODEVICES

BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function

(2012) L. M. Griep et al.   BIOMEDICAL MICRODEVICES

Organs-on-chips: breaking the in vitro impasse

(2012) Andries D. van der Meer et al.   Integrative Biology

Additive manufacturing and its societal impact: a literature review

(2012) Samuel H. Huang et al.   INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY

Laser additive manufacturing of metallic components: materials, processes and mechanisms

(2012) D D Gu et al.   INTERNATIONAL MATERIALS REVIEWS

Mesenchymal stem cells as therapeutic agents and potential targeted gene delivery vehicle for brain diseases

(2012) Bing Huang et al.   JOURNAL OF CONTROLLED RELEASE

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

Adult Neural Stem Cells: Response to Stroke Injury and Potential for Therapeutic Applications

(2012) Basam Z. Barkho et al.   Current Stem Cell Research & Therapy

Characterization of rapid PDMS casting technique utilizing molding forms fabricated by 3D rapid prototyping technology (RPT)

(2012) Attila Bonyár et al.   International Journal of Material Forming

The role of shear stress in Blood-Brain Barrier endothelial physiology

(2011) Luca Cucullo et al.   BMC NEUROSCIENCE

Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

(2011) Kathryn Hatherell et al.   JOURNAL OF NEUROSCIENCE METHODS

In Vitro Blood–Brain Barrier Models: Current and Perspective Technologies

(2011) Pooja Naik et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Co-culture Based Blood-brain Barrier In Vitro Model, a Tissue Engineering Approach using Immortalized Cell Lines for Drug Transport Study

(2010) Zhiqi Zhang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Position Statement: Definition of Traumatic Brain Injury

(2010) David K. Menon et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

A review on stereolithography and its applications in biomedical engineering

(2010) Ferry P.W. Melchels et al.   BIOMATERIALS

Pattern of P450 expression at the human blood-brain barrier: Roles of epileptic condition and laminar flow

(2010) Chaitali Ghosh et al.   EPILEPSIA

Murine in vitro model of the blood–brain barrier for evaluating drug transport

(2010) Gilda Shayan et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function

(2010) Yasuteru Sano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nuclear reprogramming to a pluripotent state by three approaches

(2010) Shinya Yamanaka et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease

(2010) Jessica F. Jordão et al.   PLoS One

Processing of a Polyamide-12/carbon nanofibre composite by laser sintering

(2010) R.D. Goodridge et al.   POLYMER TESTING

Print-and-Peel Fabrication for Microfluidics: What’s in it for Biomedical Applications?

(2009) Marlon S. Thomas et al.   ANNALS OF BIOMEDICAL ENGINEERING

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Dual response of BDNF to sublethal concentrations of β-amyloid peptides in cultured cortical neurons

(2009) E. Aliaga et al.   NEUROBIOLOGY OF DISEASE

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS

All MSCs Are Pericytes?

(2008) Arnold I. Caplan   Cell Stem Cell

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell