Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality

An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells

(2017) Scott G. Canfield et al.   JOURNAL OF NEUROCHEMISTRY

Blood-Brain Barrier Changes in High Altitude

(2016) José V. Lafuente et al.   CNS & Neurological Disorders-Drug Targets

In vitro blood–brain barrier models for drug research: state-of-the-art and new perspectives on reconstituting these models on artificial basement membrane platforms

(2016) Jayati Banerjee et al.   DRUG DISCOVERY TODAY

Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation

(2016) Miguel Alejandro Lopez-Ramirez et al.   FASEB JOURNAL

Functional Promoter Polymorphisms of MMP-2 C-735T and MMP-9 C-1562T and Their Synergism with MMP-7 A-181G in Multiple Sclerosis

(2016) Zohreh Rahimi et al.   IMMUNOLOGICAL INVESTIGATIONS

P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain

(2016) Margaret E Tome et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The blood–brain barrier after stroke: Structural studies and the role of transcytotic vesicles

(2016) Michael J Haley et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

(2016) Hans C Helms et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood–Brain Barrier Model

(2016) Jennifer L. Mantle et al.   MOLECULAR PHARMACEUTICS

Raising the standards of stem cell line quality

(2016) Michael P. Yaffe et al.   NATURE CELL BIOLOGY

Modeling Ischemic Stroke In Vitro: Status Quo and Future Perspectives

(2016) Paul M. Holloway et al.   STROKE

Stem Cell-Based Human Blood–Brain Barrier Models for Drug Discovery and Delivery

(2016) S. Aday et al.   TRENDS IN BIOTECHNOLOGY

A Review of the Mechanisms of Blood-Brain Barrier Permeability by Tissue-Type Plasminogen Activator Treatment for Cerebral Ischemia

(2016) Yasuhiro Suzuki et al.   Frontiers in Cellular Neuroscience

Human Brain Microvascular Endothelial Cells Derived from the BC1 iPS Cell Line Exhibit a Blood-Brain Barrier Phenotype

(2016) Moriah E. Katt et al.   PLoS One

Disrupted vasculature and blood-brain barrier in Huntington disease

(2015) Henry J. Waldvogel et al.   ANNALS OF NEUROLOGY

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

(2015) Janelle Drouin-Ouellet et al.   ANNALS OF NEUROLOGY

The Influence of C3435T Polymorphism of the ABCB1 Gene on Genetic Susceptibility to Depression and Treatment Response in Polish Population - Preliminary Report

(2015) Agnieszka Maria Jeleń et al.   International Journal of Medical Sciences

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

Misoprostol-induced fever and genetic polymorphisms in drug transporters SLCO1B1 and ABCC4 in women of Latin American and European ancestry

(2015) Ana Alfirevic et al.   PHARMACOGENOMICS

Blood–brain barrier dysfunction, seizures and epilepsy

(2015) E.A. van Vliet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans

(2015) Cara L. Carty et al.   STROKE

Research Progress on the Role of ABC Transporters in the Drug Resistance Mechanism of Intractable Epilepsy

(2015) Jie Xiong et al.   Biomed Research International

Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis

(2014) Steffen Mayerl et al.   JOURNAL OF CLINICAL INVESTIGATION

Compounds with species and cell type specific toxicity identified in a 2000 compound drug screen of neural stem cells and rat mixed cortical neurons

(2014) Nasir Malik et al.   NEUROTOXICOLOGY

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

(2014) Ethan S. Lippmann et al.   Scientific Reports

Transport of Thyroid Hormone in Brain

(2014) Eva K. Wirth et al.   Frontiers in Endocrinology

Inherited defects in thyroid hormone cell-membrane transport and metabolism

(2013) Jiao Fu et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Phenotypic Spectrum of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

(2013) Toni S. Pearson et al.   Current Neurology and Neuroscience Reports

GLUT1 deficiency syndrome: An update

(2013) D. Gras et al.   REVUE NEUROLOGIQUE

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells

(2013) Yiping Yan et al.   Stem Cells Translational Medicine

Insight into the Cooperation of P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) at the Blood–Brain Barrier: A Case Study Examining Sorafenib Efflux Clearance

(2012) Sagar Agarwal et al.   MOLECULAR PHARMACEUTICS

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

Classical resistance mechanisms

(2011) W. Jäger   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY