Targeting NF-κB and HIF-1 Pathways for the Treatment of Cancer: Part II

The cross-talk between NF-κB and HIF-1: further evidence for a significant liaison: Figure 1

(2015) Agnes Görlach et al.   BIOCHEMICAL JOURNAL

IFN-  Induces Transcription of Hypoxia-Inducible Factor-1  to Inhibit Proliferation of Human Endothelial Cells

(2014) S. A. Gerber et al.   JOURNAL OF IMMUNOLOGY

A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma

(2010) Brian M. Slomovitz et al.   CANCER

Suppression of Hypoxia-Inducible Factor 2  Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells

(2009) A. M. Roberts et al.   CANCER RESEARCH

Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes

(2009) Guoliang Qing et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

JunD and HIF-1α mediate transcriptional activation of angiotensinogen by TGF-β1 in human lung fibroblasts

(2009) Amal Abdul-Hafez et al.   FASEB JOURNAL

Reactive Oxygen Species-independent Oxidation of Thioredoxin in Hypoxia

(2009) Harish Muniyappa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF at a glance

(2009) M. C. Brahimi-Horn et al.   JOURNAL OF CELL SCIENCE

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Human cancers converge at the HIF-2α oncogenic axis

(2009) Aleksandra Franovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF-2  maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

(2009) A. Pietras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner

(2008) Kenichiro Nishi et al.   ANTIOXIDANTS & REDOX SIGNALING

Stem cell factor induces HIF-1α at normoxia in hematopoietic cells

(2008) Malin Pedersen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HIF-1  regulates epithelial inflammation by cell autonomous NF B activation and paracrine stromal remodeling

(2008) M. Scortegagna et al.   BLOOD

ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

(2008) Christian Moser et al.   BMC CANCER

Targeting tumour hypoxia in breast cancer

(2008) Manuela Milani et al.   EUROPEAN JOURNAL OF CANCER

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1  and -2 

(2008) M. Puppo et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia-inducible Factor-1α Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion

(2007) Elisabeth L. Pagé et al.   MOLECULAR BIOLOGY OF THE CELL