标题
Lysophospholipid Signaling in the Epithelial Ovarian Cancer Tumor Microenvironment
作者
关键词
-
出版物
Cancers
Volume 10, Issue 7, Pages 227
出版商
MDPI AG
发表日期
2018-07-09
DOI
10.3390/cancers10070227
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Platelets, autotaxin and lysophosphatidic acid signalling: win-win factors for cancer metastasis
- (2018) Raphael Leblanc et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation
- (2018) Xinyuan Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of LPA1 and LPA6 on the regulation of colony formation activity in colon cancer cells treated with anticancer drugs
- (2018) Kaede Takahashi et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Exosome Theranostics: Biology and Translational Medicine
- (2018) Chuanjiang He et al. Theranostics
- Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation
- (2018) Matthew Benesch et al. Cancers
- Autotaxin inhibitors: a patent review (2012-2016)
- (2017) Aikaterini Nikolaou et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity
- (2017) Katrina Hurst et al. HIPPOCAMPUS
- Paradoxical Association of Postoperative Plasma Sphingosine-1-Phosphate with Breast Cancer Aggressiveness and Chemotherapy
- (2017) Rajesh Ramanathan et al. MEDIATORS OF INFLAMMATION
- Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment
- (2017) Thomas Worzfeld et al. MOLECULAR & CELLULAR PROTEOMICS
- Gene regulatory networking reveals the molecular cue to lysophosphatidic acid-induced metabolic adaptations in ovarian cancer cells
- (2017) Upasana Ray et al. Molecular Oncology
- Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6
- (2017) Reiya Taniguchi et al. NATURE
- Reciprocal links between venous thromboembolism, coagulation factors and ovarian cancer progression
- (2017) Nathalie Swier et al. THROMBOSIS RESEARCH
- A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies
- (2017) Lin Cheng et al. Journal of Ovarian Research
- Sphingosine kinase 1/sphingosine-1-phosphate (S1P)/S1P receptor axis is involved in ovarian cancer angiogenesis
- (2017) Lan Dai et al. Oncotarget
- The novel ZIP4 regulation and its role in ovarian cancer
- (2017) Qipeng Fan et al. Oncotarget
- Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling
- (2017) Qianlan Fan et al. Oncotarget
- Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget
- (2017) Diana Hatoum et al. Oncotarget
- Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism
- (2017) Anna Halama et al. Scientific Reports
- Ligand chain length drives activation of lipid G protein-coupled receptors
- (2017) Anastassia Troupiotis-Tsaïlaki et al. Scientific Reports
- The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment
- (2017) Manuel Varas-Godoy et al. Stem Cells International
- Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
- (2017) Alessandro Cannavo et al. Frontiers in Pharmacology
- The Roles of Glycodelin in Cancer Development and Progression
- (2017) Juan Cui et al. Frontiers in Immunology
- Preoperative elevated platelet count and thrombocytosis in gynecologic malignancies
- (2016) Joseph Menczer ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell ActivationHighlights
- (2016) Xinyuan Li et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study
- (2016) Tilman Kühn et al. BMC Medicine
- The Emerging Role of Tyrosine Kinase Inhibitors in Ovarian Cancer Treatment: A Systematic Review
- (2016) Ioannis Ntanasis-Stathopoulos et al. CANCER INVESTIGATION
- Tumor microenvironment: The culprit for ovarian cancer metastasis?
- (2016) Zhongyue Luo et al. CANCER LETTERS
- Mammary Adipose Tissue-Derived Lysophospholipids Promote Estrogen Receptor-Negative Mammary Epithelial Cell Proliferation
- (2016) P. A. Volden et al. Cancer Prevention Research
- Metabolomics of biomarker discovery in ovarian cancer: a systematic review of the current literature
- (2016) Onur Turkoglu et al. Metabolomics
- Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism
- (2016) Eun Jin Seo et al. STEM CELLS
- High resolution mass spectrometry coupled with multivariate data analysis revealing plasma lipidomic alteration in ovarian cancer in Asian women
- (2016) Yangyang Zhang et al. TALANTA
- The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined
- (2016) Lei Jin et al. World Journal of Surgical Oncology
- Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus
- (2016) Ji Hee Ha et al. Oncotarget
- Metabolic phenotyping for monitoring ovarian cancer patients
- (2016) Chaofu Ke et al. Scientific Reports
- Synergistic COX2 Induction by IFN and TNF Self-Limits Type-1 Immunity in the Human Tumor Microenvironment
- (2016) J. L. Wong et al. Cancer Immunology Research
- The molecular mechanism by which saturated lysophosphatidylcholine attenuates the metastatic capacity of melanoma cells
- (2016) Thomas Ross et al. FEBS Open Bio
- Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment
- (2016) Yamila I. Rodriguez et al. Frontiers in Oncology
- Diverse effects of LPA4, LPA5 and LPA6 on the activation of tumor progression in pancreatic cancer cells
- (2015) Shuhei Ishii et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Promising Pharmacological Directions in the World of Lysophosphatidic Acid Signaling
- (2015) Nicole C. Stoddard et al. Biomolecules & Therapeutics
- A review of HER2-targeted therapy in breast and ovarian cancer: lessons from antiquity – CLEOPATRA and PENELOPE
- (2015) Melissa Hodeib et al. Future Oncology
- Diagnostic Value of Total Plasma Lysophosphatidic Acid in Ovarian Cancer
- (2015) Zhaolian Lu et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma
- (2015) Rebecca J. Burkhalter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical significance of plasma lysophosphatidic acid levels in the differential diagnosis of ovarian cancer
- (2015) Yun-Jie Zhang et al. Journal of Cancer Research and Therapeutics
- Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage
- (2015) Meta Michels et al. JOURNAL OF INFECTION
- Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate
- (2015) Matthew G. K. Benesch et al. JOURNAL OF LIPID RESEARCH
- Lysophosphatidic acid signaling in ovarian cancer
- (2015) Anna Jesionowska et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Venous thrombosis and cancer: from mouse models to clinical trials
- (2015) Y. Hisada et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The Lipidomic Analyses in Low and Highly Aggressive Ovarian Cancer Cell Lines
- (2015) Zhenwen Zhao et al. LIPIDS
- Plasma levels of lysophosphatidic acid in ovarian cancer versus controls: a meta-analysis
- (2015) Yi-Yang Li et al. Lipids in Health and Disease
- MicroRNA-148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine-1-phosphate receptor 1
- (2015) ZHENGFANG WEN et al. Molecular Medicine Reports
- Decreased Peritoneal Ovarian Cancer Growth in Mice Lacking Expression of Lipid Phosphate Phosphohydrolase 1
- (2015) John Nakayama et al. PLoS One
- Decreased expression of lysophosphatidylcholine (16:0/OH) in high resolution imaging mass spectrometry independently predicts biochemical recurrence after surgical treatment for prostate cancer
- (2015) Takayuki Goto et al. PROSTATE
- Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer
- (2015) Jessica A. Beach et al. Oncotarget
- FOXM1 is a downstream target of LPA and YAP oncogenic signaling pathways in high grade serous ovarian cancer
- (2015) Qipeng Fan et al. Oncotarget
- In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
- (2015) Venkatesh Krishnan et al. Jove-Journal of Visualized Experiments
- Paraneoplastic thrombocytosis: the secrets of tumor self-promotion
- (2014) R. J. Lin et al. BLOOD
- Sphingosine 1-phosphate: A Potential Molecular Target for Ovarian Cancer Therapy?
- (2014) Lan Dai et al. CANCER INVESTIGATION
- Tumor-derived exosomes in oncogenic reprogramming and cancer progression
- (2014) Sarmad N. Saleem et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Autotaxin-LPA Axis Emerges as a Novel Regulator of Lymphocyte Homing and Inflammation
- (2014) S. Knowlden et al. JOURNAL OF IMMUNOLOGY
- LPA receptor signaling: pharmacology, physiology, and pathophysiology
- (2014) Yun C. Yung et al. JOURNAL OF LIPID RESEARCH
- Anoikis resistance is a critical feature of highly aggressive ovarian cancer cells
- (2014) Q Cai et al. ONCOGENE
- Regulation of T Cell Motility In Vitro and In Vivo by LPA and LPA2
- (2014) Sara A. Knowlden et al. PLoS One
- Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of In Vitro Morphological Subtypes
- (2014) Corine M. Beaufort et al. PLoS One
- Exosomes: an overview of biogenesis, composition and role in ovarian cancer
- (2014) Allison Beach et al. Journal of Ovarian Research
- Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
- (2014) Masayuki Nagahashi et al. Biomed Research International
- Effect of alkyl glycerophosphate on the activation of peroxisome proliferator-activated receptor gamma and glucose uptake in C2C12 cells
- (2013) Tamotsu Tsukahara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition
- (2013) Benoît Thibault et al. CANCER AND METASTASIS REVIEWS
- The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells
- (2013) Hui Cai et al. Cell Communication and Signaling
- Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond
- (2013) Gregory T. Kunkel et al. NATURE REVIEWS DRUG DISCOVERY
- Elevated Phospholipase A2 Activities in Plasma Samples from Multiple Cancers
- (2013) Hui Cai et al. PLoS One
- Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation
- (2013) Alan Brito Carneiro et al. PLoS One
- Evaluating cell lines as tumour models by comparison of genomic profiles
- (2013) Silvia Domcke et al. Nature Communications
- Elevated and secreted phospholipase A2 activities as new potential therapeutic targets in human epithelial ovarian cancer
- (2012) Qingchun Cai et al. FASEB JOURNAL
- Serum Autotaxin is not a Useful Biomarker for Ovarian Cancer
- (2012) Kazuhiro Nakamura et al. LIPIDS
- Combination Therapy of an Inhibitor of Group VIA Phospholipase A 2 with Paclitaxel Is Highly Effective in Blocking Ovarian Cancer Development
- (2011) Hui Li et al. AMERICAN JOURNAL OF PATHOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid
- (2011) Rodolphe Dusaulcy et al. JOURNAL OF LIPID RESEARCH
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation
- (2010) Ashley J. Snider et al. BIOCHIMIE
- S1P2, the G Protein-Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth In vivo in Mice
- (2010) W. Du et al. CANCER RESEARCH
- Endothelial Functions of Sphingosine-1-phosphate
- (2010) Susann Lucke et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development
- (2010) Hui Li et al. FASEB JOURNAL
- Sphingosine Kinase Mediates Resistance to the Synthetic RetinoidN-(4-Hydroxyphenyl)retinamide in Human Ovarian Cancer Cells
- (2010) Giuditta Illuzzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain
- (2010) L. Ma et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- An update on sphingosine-1-phosphate and other sphingolipid mediators
- (2010) Henrik Fyrst et al. Nature Chemical Biology
- Roles of LPA in ovarian cancer development and progression
- (2009) Tarah L Pua et al. Future Oncology
- The Absence of LPA2 Attenuates Tumor Formation in an Experimental Model of Colitis-Associated Cancer
- (2009) Songbai Lin et al. GASTROENTEROLOGY
- Highlights of a new type of intercellular communication: microvesicle-based information transfer
- (2009) E. Pap et al. INFLAMMATION RESEARCH
- Measurement of endogenous lysophosphatidic acid by ESI-MS/MS in plasma samples requires pre-separation of lysophosphatidylcholine
- (2009) Zhenwen Zhao et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Inhibitory Role of Sphingosine 1-Phosphate Receptor 2 in Macrophage Recruitment during Inflammation
- (2009) J. Michaud et al. JOURNAL OF IMMUNOLOGY
- An extremely simple method for extraction of lysophospholipids and phospholipids from blood samples
- (2009) Zhenwen Zhao et al. JOURNAL OF LIPID RESEARCH
- Lysophosphatidic acid stimulates cell migration, invasion, and colony formation as well as tumorigenesis/metastasis of mouse ovarian cancer in immunocompetent mice
- (2009) H. Li et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
- (2009) N. C. Hait et al. SCIENCE
- Inhibition of Lysophosphatidic Acid Receptor-2 Expression by RNA Interference Decreases Lysophosphatidic Acid-induced Urokinase Plasminogen Activator Activation, Cell Invasion, and Migration in Ovarian Cancer SKOV-3 Cells
- (2008) Gui-li Wang et al. CROATIAN MEDICAL JOURNAL
- Targeting SphK1 as a New Strategy against Cancer
- (2008) Dai Shida et al. CURRENT DRUG TARGETS
- S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment are mediated by Gi and Rac
- (2008) Kathleen M. Devine et al. GYNECOLOGIC ONCOLOGY
- MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
- (2008) Douglas D. Taylor et al. GYNECOLOGIC ONCOLOGY
- LPA receptor 2 mediates LPA-induced endometrial cancer invasion
- (2008) Joanie Mayer Hope et al. GYNECOLOGIC ONCOLOGY
- Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1α and the PI3K pathway
- (2008) Kun Yang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Update of the LIPID MAPS comprehensive classification system for lipids
- (2008) Eoin Fahy et al. JOURNAL OF LIPID RESEARCH
- S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells
- (2008) D. Wang et al. MOLECULAR CANCER THERAPEUTICS
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