Engineering of obligate intracellular bacteria: progress, challenges and paradigms

Molecular Genetic Analysis ofChlamydiaSpecies

(2016) Barbara S. Sixt et al.   Annual Review of Microbiology

Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread

(2016) Rebecca L. Lamason et al.   CELL

Nonselective Persistence of a Rickettsia conorii Extrachromosomal Plasmid during Mammalian Infection

(2016) Sean P. Riley et al.   INFECTION AND IMMUNITY

The Chlamydia-Secreted Protease CPAF Promotes Chlamydial Survival in the Mouse Lower Genital Tract

(2016) Zhangsheng Yang et al.   INFECTION AND IMMUNITY

Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis

(2016) Edgar Sanchez et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interrogating Genes That Mediate Chlamydia trachomatis Survival in Cell Culture Using Conditional Mutants and Recombination

(2016) Julie A. Brothwell et al.   JOURNAL OF BACTERIOLOGY

AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

(2016) Daniel Prantner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen

(2016) Robert J. Bastidas et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Chlamydia cell biology and pathogenesis

(2016) Cherilyn Elwell et al.   NATURE REVIEWS MICROBIOLOGY

Endemic Scrub Typhus in South America

(2016) Thomas Weitzel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fluorescence Activated Cell Sorting of Rickettsia prowazekii-Infected Host Cells Based on Bacterial Burden and Early Detection of Fluorescent Rickettsial Transformants

(2016) Lonnie O. Driskell et al.   PLoS One

Gene Deletion by Fluorescence-Reported Allelic Exchange Mutagenesis in Chlamydia trachomatis

(2016) Konrad E. Mueller et al.   mBio

Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation

(2016) Michael John Patton et al.   mBio

TheRickettsiatype IV secretion system: unrealized complexity mired by gene family expansion

(2016) Joseph J. Gillespie et al.   Pathogens and Disease

Integrating Chemical Mutagenesis and Whole-Genome Sequencing as a Platform for Forward and Reverse Genetic Analysis of Chlamydia

(2015) Marcela Kokes et al.   Cell Host & Microbe

Coxiella burnetii: turning hostility into a home

(2015) Jennifer H. Moffatt et al.   CELLULAR MICROBIOLOGY

Human and Pathogen Factors Associated with Chlamydia trachomatis-Related Infertility in Women

(2015) S. Menon et al.   CLINICAL MICROBIOLOGY REVIEWS

Attenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host

(2015) Arathy D. S. Nair et al.   INFECTION AND IMMUNITY

Isolation of single Chlamydia-infected cells using laser microdissection

(2015) Oleg V. Podgorny et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Membrane Perturbation-Associated Ca2+Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry

(2015) David N. Hare et al.   JOURNAL OF VIROLOGY

Dendrimer-enabled transformation of Anaplasma phagocytophilum

(2015) Aminat T. Oki et al.   MICROBES AND INFECTION

Application of β-Lactamase Reporter Fusions as an Indicator of Effector Protein Secretion during Infections with the Obligate Intracellular Pathogen Chlamydia trachomatis

(2015) Konrad E. Mueller et al.   PLoS One

Targeted Knockout of the Rickettsia rickettsii OmpA Surface Antigen Does Not Diminish Virulence in a Mammalian Model System

(2015) Nicholas F. Noriea et al.   mBio

Which Way In? The RalF Arf-GEF Orchestrates Rickettsia Host Cell Invasion

(2015) Kristen E. Rennoll-Bankert et al.   PLoS Pathogens

Mutations in Ehrlichia chaffeensis Causing Polar Effects in Gene Expression and Differential Host Specificities

(2015) Chuanmin Cheng et al.   PLoS One

Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting

(2015) Lori Newman et al.   PLoS One

Knockout of an outer membrane protein operon of Anaplasma marginale by transposon mutagenesis

(2014) Francy L Crosby et al.   BMC GENOMICS

Genotyping, evolution and epidemiological findings of Rickettsia species

(2014) Vicky Merhej et al.   INFECTION GENETICS AND EVOLUTION

Expression and Targeting of Secreted Proteins from Chlamydia trachomatis

(2014) L. D. Bauler et al.   JOURNAL OF BACTERIOLOGY

Trachoma

(2014) Hugh R Taylor et al.   LANCET

Mechanisms of plasmid segregation: Have multicopy plasmids been overlooked?

(2014) Samuel Million-Weaver et al.   PLASMID

Site-Specific, Insertional Inactivation of incA in Chlamydia trachomatis Using a Group II Intron

(2014) Cayla M. Johnson et al.   PLoS One

Analysis of CPAF mutants: new functions, new questions (The ins and outs of a chlamydial protease)

(2014) Patrik M. Bavoil et al.   Pathogens and Disease

Reassessing the role of the secreted protease CPAF inChlamydia trachomatisinfection through genetic approaches

(2014) Emily A. Snavely et al.   Pathogens and Disease

Ankyrin domains across the Tree of Life

(2014) Kristin K. Jernigan et al.   PeerJ

Motility Characteristics Are Altered for Rickettsia bellii Transformed To Overexpress a HeterologousrickAGene

(2013) Jonathan D. Oliver et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rickettsia Actin-Based Motility Occurs in Distinct Phases Mediated by Different Actin Nucleators

(2013) Shawna C.O. Reed et al.   CURRENT BIOLOGY

Recent molecular insights into rickettsial pathogenesis and immunity

(2013) Sanjeev K Sahni et al.   Future Microbiology

Dendrimer-enabled DNA delivery and transformation of Chlamydia pneumoniae

(2013) Hervé C. Gérard et al.   Nanomedicine-Nanotechnology Biology and Medicine

Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii

(2013) Erin J. van Schaik et al.   NATURE REVIEWS MICROBIOLOGY

A C. trachomatis Cloning Vector and the Generation of C. trachomatis Strains Expressing Fluorescent Proteins under the Control of a C. trachomatis Promoter

(2013) Hervé Agaisse et al.   PLoS One

Conditional Gene Expression in Chlamydia trachomatis Using the Tet System

(2013) Jason Wickstrum et al.   PLoS One

Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

(2013) Victor H. Hu et al.   PLoS Neglected Tropical Diseases

Targeted and Random Mutagenesis of Ehrlichia chaffeensis for the Identification of Genes Required for In vivo Infection

(2013) Chuanmin Cheng et al.   PLoS Pathogens

Anaplasma phagocytophilum—a widespread multi-host pathogen with highly adaptive strategies

(2013) Snorre Stuen et al.   Frontiers in Cellular and Infection Microbiology

Approaches to vaccines against Orientia tsutsugamushi

(2013) Gustavo Valbuena et al.   Frontiers in Cellular and Infection Microbiology

Two Systems for Targeted Gene Deletion in Coxiella burnetii

(2012) Paul A. Beare et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Evolution and Conservation of Predicted Inclusion Membrane Proteins in Chlamydiae

(2012) Erika I. Lutter et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Anaplasma phagocytophilum Dihydrolipoamide Dehydrogenase 1 Affects Host-Derived Immunopathology during Microbial Colonization

(2012) Gang Chen et al.   INFECTION AND IMMUNITY

Dendrimer-Enabled Modulation of Gene Expression in Chlamydia trachomatis

(2012) Manoj K. Mishra et al.   MOLECULAR PHARMACEUTICS

Establishment of a Replicating Plasmid in Rickettsia prowazekii

(2012) David O. Wood et al.   PLoS One

Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches

(2012) B. D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPAF: A Chlamydial Protease in Search of an Authentic Substrate

(2012) Allan L. Chen et al.   PLoS Pathogens

The Capping Domain in RalF Regulates Effector Functions

(2012) Eric Alix et al.   PLoS Pathogens

Increasing Incidence of Ehrlichia chaffeensis and Anaplasma phagocytophilum in the United States, 2000–2007

(2011) F. Scott Dahlgren et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Worldwide detection and identification of new and old rickettsiae and rickettsial diseases: Figure 1

(2011) Allen L. Richards   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

The biological basis of severe outcomes inAnaplasma phagocytophiluminfection

(2011) J. Stephen Dumler   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Bacterial Virulence in the Moonlight: Multitasking Bacterial Moonlighting Proteins Are Virulence Determinants in Infectious Disease

(2011) Brian Henderson et al.   INFECTION AND IMMUNITY

The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates

(2011) D. E. Voth et al.   JOURNAL OF BACTERIOLOGY

TheRickettsiaSurface Cell Antigen 4 Applies Mimicry to Bind to and Activate Vinculin

(2011) HaJeung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subversion of host cell signaling by Orientia tsutsugamushi

(2011) Yan Ge et al.   MICROBES AND INFECTION

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Development of Shuttle Vectors for Transformation of Diverse Rickettsia Species

(2011) Nicole Y. Burkhardt et al.   PLoS One

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of targeted Chlamydia trachomatis null mutants

(2011) L. Kari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a Transformation System for Chlamydia trachomatis: Restoration of Glycogen Biosynthesis by Acquisition of a Plasmid Shuttle Vector

(2011) Yibing Wang et al.   PLoS Pathogens

Advances in Genetic Manipulation of Obligate Intracellular Bacterial Pathogens

(2011) Paul A. Beare et al.   Frontiers in Microbiology

Life on the Outside: The Rescue ofCoxiella burnetiifrom Its Host Cell

(2010) Anders Omsland et al.   Annual Review of Microbiology

Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins

(2010) Yasuko Rikihisa et al.   CURRENT OPINION IN MICROBIOLOGY

Immunology Taught by Bacteria

(2010) Russell E. Vance   JOURNAL OF CLINICAL IMMUNOLOGY

Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells

(2010) Yasuko Rikihisa   NATURE REVIEWS MICROBIOLOGY

Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii

(2010) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Group II Introns: Mobile Ribozymes that Invade DNA

(2010) A. M. Lambowitz et al.   Cold Spring Harbor Perspectives in Biology

Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain

(2009) Helena MB Seth-Smith et al.   BMC GENOMICS

Directed Mutagenesis of the Rickettsia prowazekii pld Gene Encoding Phospholipase D

(2009) L. O. Driskell et al.   INFECTION AND IMMUNITY

Transformation of Anaplasma marginale

(2009) Roderick F. Felsheim et al.   VETERINARY PARASITOLOGY

The Whole-genome Sequencing of the Obligate Intracellular Bacterium Orientia tsutsugamushi Revealed Massive Gene Amplification During Reductive Genome Evolution

(2008) K. Nakayama et al.   DNA RESEARCH

Characterization of a Coxiella burnetii ftsZ Mutant Generated by Himar1 Transposon Mutagenesis

(2008) P. A. Beare et al.   JOURNAL OF BACTERIOLOGY

Transformation and isolation of allelic exchange mutants of Chlamydia psittaci using recombinant DNA introduced by electroporation

(2008) R. Binet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA