AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling
出版年份 2016 全文链接
标题
AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 1, Pages 292-304
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2016-11-23
DOI
10.1074/jbc.m116.763268
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy
- (2015) Weili Tian et al. FEBS LETTERS
- RIG-I is required for VSV-induced cytokine production by murine glia and acts in combination with DAI to initiate responses to HSV-1
- (2015) Emma K. Crill et al. GLIA
- Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates
- (2015) Daniel F. Egan et al. MOLECULAR CELL
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses
- (2015) Zhe Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2
- (2013) Fiona McAlpine et al. Autophagy
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
- (2013) Pu Gao et al. CELL
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma
- (2013) L. Zheng et al. CLINICAL CANCER RESEARCH
- Species-specific detection of the antiviral small-molecule compound CMA by STING
- (2013) Taner Cavlar et al. EMBO JOURNAL
- Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease
- (2013) Lake Li et al. FOOD AND CHEMICAL TOXICOLOGY
- Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
- (2013) J. Conlon et al. JOURNAL OF IMMUNOLOGY
- AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling
- (2013) Kelly Casey Carroll et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells
- (2013) Angela Kwok-Fung Lo et al. JOURNAL OF PATHOLOGY
- Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade
- (2013) E. Lam et al. JOURNAL OF VIROLOGY
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- ELF4 is critical for induction of type I interferon and the host antiviral response
- (2013) Fuping You et al. NATURE IMMUNOLOGY
- Mitochondrial calcium uptake
- (2013) G. S. B. Williams et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
- (2013) D. Gao et al. SCIENCE
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization
- (2012) Hildegard I.D. Mack et al. Autophagy
- Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase
- (2012) Chan Sun Park et al. BIOCHEMICAL PHARMACOLOGY
- Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages
- (2012) Paolo S. Manzanillo et al. Cell Host & Microbe
- AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma
- (2012) Seoung Ju Park et al. INFLAMMATION RESEARCH
- 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
- (2012) Daniel Prantner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium/Calmodulin-dependent Protein Kinase Kinase 2: Roles in Signaling and Pathophysiology
- (2012) Luigi Racioppi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- AMP-activated protein kinase-α1 as an activating kinase of TGF-β-activated kinase 1 has a key role in inflammatory signals
- (2012) S Y Kim et al. Cell Death & Disease
- AMP-Activated Kinase Restricts Rift Valley Fever Virus Infection by Inhibiting Fatty Acid Synthesis
- (2012) Theresa S. Moser et al. PLoS Pathogens
- Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo
- (2011) Young Min Kim et al. ATHEROSCLEROSIS
- The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
- (2011) Markus Bach et al. BIOCHEMICAL JOURNAL
- MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
- (2011) L. Jin et al. JOURNAL OF IMMUNOLOGY
- Inhibition of hepatitis C virus replication through adenosine monophosphate-activated protein kinase-dependent and -independent pathways
- (2011) Kenji Nakashima et al. MICROBIOLOGY AND IMMUNOLOGY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors
- (2011) Jae-Min Yuk et al. NATURE IMMUNOLOGY
- MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection
- (2011) Leonardo A. de Almeida et al. PLoS One
- Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
- (2011) L. Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB
- (2010) Marina Katerelos et al. IMMUNOLOGY AND CELL BIOLOGY
- TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
- (2010) John-Demian Sauer et al. INFECTION AND IMMUNITY
- Stimulator of IFN Gene Is Critical for Induction of IFN-β during Chlamydia muridarum Infection
- (2010) Daniel Prantner et al. JOURNAL OF IMMUNOLOGY
- The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-β-mediated antiviral activity in vitro and in vivo
- (2010) Kari Ann Shirey et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
- (2010) J. W. Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- A Kinome RNAi Screen Identified AMPK as Promoting Poxvirus Entry through the Control of Actin Dynamics
- (2010) Theresa S. Moser et al. PLoS Pathogens
- AMPK: Lessons from transgenic and knockout animals
- (2009) Benoit Viollet Frontiers in Bioscience-Landmark
- Mapping the Phosphorylation Sites of Ulk1
- (2009) Frank C. Dorsey et al. JOURNAL OF PROTEOME RESEARCH
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
- (2009) T. Saitoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
- Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase
- (2007) Chih-Lin Kuo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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