The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

(2015) Jin Huang et al.   AGEING RESEARCH REVIEWS

DAMPs activating innate immune responses in sepsis

(2015) Jung-Woo Kang et al.   AGEING RESEARCH REVIEWS

Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex

(2015) Minho Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intracellular ROS Generation Mediates Maleimide-induced Cytotoxicity in Leukemia Cells

(2015) Daiane Rosolen et al.   Anti-Cancer Agents in Medicinal Chemistry

ROS and energy metabolism in cancer cells: alliance for fast growth

(2015) Sang Won Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Glutaminolysis and autophagy in cancer

(2015) Victor H Villar et al.   Autophagy

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

Molecular dynamics simulations of the transport of reactive oxygen species by mammalian and plant aquaporins

(2015) Rodrigo M. Cordeiro   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

On the effect of serum on the transport of reactive oxygen species across phospholipid membranes

(2015) Endre J. Szili et al.   Biointerphases

SIRT2 suppresses non-small cell lung cancer growth by targeting JMJD2A

(2015) Weihua Xu et al.   BIOLOGICAL CHEMISTRY

Role of the interaction between galectin-3 and cell adhesion molecules in cancer metastasis

(2015) Ming Xin et al.   BIOMEDICINE & PHARMACOTHERAPY

Tumour-suppressive function of SIRT4 in human colorectal cancer

(2015) M Miyo et al.   BRITISH JOURNAL OF CANCER

Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells

(2015) V O Okoh et al.   BRITISH JOURNAL OF CANCER

Sirtuin 6 promotes transforming growth factor-β1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence

(2015) Xin-Xia Feng et al.   CANCER SCIENCE

SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner

(2015) Zhu Xu et al.   CELL CYCLE

NADPH oxidases and cancer

(2015) Krishnendu Roy et al.   CLINICAL SCIENCE

Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure

(2015) R. Pagliarini et al.   EMBO REPORTS

Sirtuin 6 protects the heart from hypoxic damage

(2015) Anna Maksin-Matveev et al.   EXPERIMENTAL CELL RESEARCH

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

(2015) Shashi Kiran et al.   EXPERIMENTAL CELL RESEARCH

DNA damage checkpoint recovery and cancer development

(2015) Haiyong Wang et al.   EXPERIMENTAL CELL RESEARCH

Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment

(2015) Eui Jung Moon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress induced by cadmium in the plasma, erythrocytes and lymphocytes of rats

(2015) B Nazima et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes

(2015) Kyle G. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Damage to RPA Limits the Nucleotide Excision Repair Capacity of Human Cells

(2015) Melisa Guven et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Primary breast cancer induces pulmonary vascular hyperpermeability and promotes metastasis via the VEGF-PKC pathway

(2015) Man Jiang et al.   MOLECULAR CARCINOGENESIS

Oxidative and nitrative stress in neurodegeneration

(2015) Catherine A. Cobb et al.   NEUROBIOLOGY OF DISEASE

The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia

(2015) M.-K. Chung et al.   NEUROSCIENCE

Expanding on Exosomes and Ectosomes in Cancer

(2015) Lorraine O’Driscoll   NEW ENGLAND JOURNAL OF MEDICINE

Causality and Chance in the Development of Cancer

(2015) Lucio Luzzatto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enhancement of SOX-2 expression and ROS accumulation by culture of A172 glioblastoma cells under non-adherent culture conditions

(2015) CHANG-NIM IM et al.   ONCOLOGY REPORTS

New Insights for Oxidative Stress and Diabetes Mellitus

(2015) Kenneth Maiese   Oxidative Medicine and Cellular Longevity

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism

(2015) Emelyn H. Shroff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway

(2015) Sasidharan Padmaja Divya et al.   TOXICOLOGICAL SCIENCES

Cancer cell-derived IL-8 induces monocytic THP1 cells to secrete IL-8 via the mitogen-activated protein kinase pathway

(2015) Yukina Nishio et al.   TUMOR BIOLOGY

Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells

(2015) Sapna Singh et al.   TUMOR BIOLOGY

Inhibition of ROS and inflammation by an imidazopyridine derivative X22 attenuate high fat diet-induced arterial injuries

(2015) Weixin Li et al.   VASCULAR PHARMACOLOGY

On the effect of serum on the transport of reactive oxygen species across phospholipid membranes

(2015) Endre J. Szili et al.   Biointerphases

Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway

(2015) Yizhou Quan et al.   Scientific Reports

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

(2015) Shivani Malik et al.   Scientific Reports

One Special Question to Start with: Can HIF/NFkB be a Target in Inflammation?

(2015) Matteo Russo et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Hyaluronan, Inflammation, and Breast Cancer Progression

(2015) Kathryn L. Schwertfeger et al.   Frontiers in Immunology

Oxygen in human health from life to death – An approach to teaching redox biology and signaling to graduate and medical students

(2015) Margaret M. Briehl   Redox Biology

The Histone Deacetylase SIRT6: At the Crossroads Between Epigenetics, Metabolism and Disease

(2015) Jean-Pierre Etchegaray et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Expression of Sirtuin 1 and 2 Is Associated with Poor Prognosis in Non-Small Cell Lung Cancer Patients

(2015) Ivana Grbesa et al.   PLoS One

HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer

(2015) Wenjing Zhang et al.   PLoS One

SIRT2 ameliorates lipopolysaccharide-induced inflammation in macrophages

(2014) Ae Sin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia

(2014) Anne H.-H. Tseng et al.   BIOCHEMICAL JOURNAL

The Basic Biology of Redoxosomes in Cytokine-Mediated Signal Transduction and Implications for Disease-Specific Therapies

(2014) Netanya Y. Spencer et al.   BIOCHEMISTRY

C-reactive protein level is a prognostic indicator for survival and improves the predictive ability of the R-IPI score in diffuse large B-cell lymphoma patients

(2014) K T Troppan et al.   BRITISH JOURNAL OF CANCER

Activin Upregulation by NF- B Is Required to Maintain Mesenchymal Features of Cancer Stem-like Cells in Non-Small Cell Lung Cancer

(2014) J. J. Wamsley et al.   CANCER RESEARCH

FSL-1 Induces MMP-9 Production through TLR-2 and NF-κB /AP-1 Signaling Pathways in Monocytic THP-1 Cells

(2014) Rasheed Ahmad et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress

(2014) G. Saretzki   CURRENT PHARMACEUTICAL DESIGN

Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming

(2014) B. M. M. Zwaans et al.   Disease Models & Mechanisms

Serum amyloid A promotes osteosarcoma invasion via upregulating αvβ3 integrin

(2014) PENG REN et al.   Molecular Medicine Reports

Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

(2014) Apolinar Maya-Mendoza et al.   Molecular Oncology

Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model

(2014) Lingling Zeng et al.   PLoS One

Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H2O2-Induced 5-Lipoxygenase

(2014) Kristi M. Porter et al.   PLoS One

HIF-1α Inhibition Reverses Multidrug Resistance in Colon Cancer Cells via Downregulation of MDR1/P-Glycoprotein

(2014) Jianfang Chen et al.   PLoS One

A novel NF-κB/MMP-3 signal pathway involves in the aggressivity of glioma promoted by Bmi-1

(2014) Piyun Sun et al.   TUMOR BIOLOGY

Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-κB pathway

(2014) Wenwen Zhao et al.   VASCULAR PHARMACOLOGY

SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth

(2014) L Ma et al.   Cell Death & Disease

RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer

(2014) R Kang et al.   Cell Death & Disease

Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6

(2014) Rong Liu et al.   Biomed Research International

Overexpression of Sirtuin 6 Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis

(2013) Hwa-Suk Lee et al.   ARTHRITIS AND RHEUMATISM

Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism

(2013) Amrita Ahluwalia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT5 desuccinylates and activates SOD1 to eliminate ROS

(2013) Zhi-Feng Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

(2013) Seung Min Jeong et al.   CANCER CELL

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

PEP-1–SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages

(2013) Mi Jin Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT4 Protein Suppresses Tumor Formation in Genetic Models of Myc-induced B Cell Lymphoma

(2013) Seung Min Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species activation of MAPK pathway results in VEGF upregulation as an undesired irradiation response

(2013) Martynas Drigotas et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

The Nexus between VEGF and NFκB Orchestrates a Hypoxia-Independent Neovasculogenesis

(2013) Michael DeNiro et al.   PLoS One

Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment

(2013) Miyako Kondoh et al.   PLoS One

Proteomic analysis of seminal fluid from men exhibiting oxidative stress

(2013) Rakesh Sharma et al.   Reproductive Biology and Endocrinology

Altered expression of SIRT gene family in head and neck squamous cell carcinoma

(2013) Chi-Chih Lai et al.   TUMOR BIOLOGY

Exosomes as nucleic acid nanocarriers

(2012) Jasper G. van den Boorn et al.   ADVANCED DRUG DELIVERY REVIEWS

Redox modulation of the DNA damage response

(2012) Fanny Caputo et al.   BIOCHEMICAL PHARMACOLOGY

RETRACTED: Sirtuin-4 modulates sensitivity to induction of the mitochondrial permeability transition pore

(2012) Manish Verma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Overexpression of pro-inflammatory genes and down-regulation of SOCS-1 in human PTC and in hypoxic BCPAP cells

(2012) Elena De Santis et al.   BIOMEDICINE & PHARMACOTHERAPY

Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma

(2012) Cardin Romilda et al.   BMC CANCER

SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH

(2012) L Pellegrini et al.   CELL DEATH AND DIFFERENTIATION

High-Fat Diet Triggers Inflammation-Induced Cleavage of SIRT1 in Adipose Tissue To Promote Metabolic Dysfunction

(2012) Angeliki Chalkiadaki et al.   Cell Metabolism

Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF

(2012) Sae-Won Lee et al.   EMBO Molecular Medicine

Oxidative stress as a potential biomarker for determining disease activity in patients with Rheumatoid Arthritis

(2012) Sunanda Kundu et al.   FREE RADICAL RESEARCH

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Effects of hypoxia and HIFs on cancer metabolism

(2012) Vera Mucaj et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Anti-Inflammatory Properties of Sirtuin 6 in Human Umbilical Vein Endothelial Cells

(2012) Martha Lappas   MEDIATORS OF INFLAMMATION

Redox regulation of cancer cell migration and invasion

(2012) Lalchhandami Tochhawng et al.   MITOCHONDRION

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions

(2012) Alexander Laemmle et al.   PLoS One

Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue

(2012) Hassina Massudi et al.   PLoS One

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

(2012) Melanie Gertz et al.   PLoS One

Redox Regulation of Mitochondrial Function

(2011) Diane E. Handy et al.   ANTIOXIDANTS & REDOX SIGNALING

Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes

(2011) Mona Dvir-Ginzberg et al.   ARTHRITIS AND RHEUMATISM

ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells

(2011) Mahandranauth A. Chetram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation

(2011) Ya-ting Tina Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

(2011) Marco Tafani et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Telomerase activity in response to mild oxidative stress

(2011) Norma Edith López‑Diazguerrero et al.   CELL BIOLOGY INTERNATIONAL

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

(2011) L Qiang et al.   CELL DEATH AND DIFFERENTIATION

Cancer Stem Cells and Chemosensitivity

(2011) M. Maugeri-Sacca et al.   CLINICAL CANCER RESEARCH

Suppressor of cytokine signaling proteins as regulators of innate immune signaling

(2011) Julia Strebovsky   Frontiers in Bioscience-Landmark

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

Reactive Oxygen Species Released from Hypoxic Hepatocytes Regulates MMP-2 Expression in Hepatic Stellate Cells

(2011) Jing Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis

(2011) Seong-Hoon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ROS-induced ZNF580 expression: a key role for H2O2/NF-κB signaling pathway in vascular endothelial inflammation

(2011) Ren DangLi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reactive Oxygen Species (ROS)––Induced genetic and epigenetic alterations in human carcinogenesis

(2011) Dominique Ziech et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair

(2011) F. Jiang et al.   PHARMACOLOGICAL REVIEWS

Targeting DNA damage and repair: Embracing the pharmacological era for successful cancer therapy

(2011) K. Aziz et al.   PHARMACOLOGY & THERAPEUTICS

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Regulation of SIRT1 in cellular functions: Role of polyphenols

(2010) Sangwoon Chung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glutaminolysis yields a metabolic by-product that stimulates autophagy

(2010) Christina H. Eng et al.   Autophagy

Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

(2010) Marco Tafani et al.   CANCER SCIENCE

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Suppressor of cytokine signaling 1 (SOCS1) limits NFκB signaling by decreasing p65 stability within the cell nucleus

(2010) Julia Strebovsky et al.   FASEB JOURNAL

Reactive oxygen species: A radical role in development?

(2010) David Hernández-García et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

NF-κ B-dependent upregulation of ICAM-1 by HPV16-E6/E7 facilitates NK cell/target cell interaction

(2010) Sonja Textor et al.   INTERNATIONAL JOURNAL OF CANCER

Roles of SIRT1 in the Acute and Restorative Phases following Induction of Inflammation

(2010) Zhiyong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310

(2010) K. M. Rothgiesser et al.   JOURNAL OF CELL SCIENCE

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion

(2010) Nicolas Tobar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

An Essential Role of the HIF-1α-c-Myc Axis in Malignant Progression

(2009) Young-Gun Yoo et al.   Annals of the New York Academy of Sciences

Inflammation, Microenvironment, and the Immune System in Cancer Progression

(2009) Andrew Keibel et al.   CURRENT PHARMACEUTICAL DESIGN

Chemokine (C-C Motif) Ligand 2 Engages CCR2+Stromal Cells of Monocytic Origin to Promote Breast Cancer Metastasis to Lung and Bone

(2009) Xin Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma

(2009) Linda Ravenna et al.   PROSTATE

Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

(2009) D. J. Gough et al.   SCIENCE

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCɛ signaling axis in pulmonary artery smooth muscle cells

(2008) R RATHORE et al.   FREE RADICAL BIOLOGY AND MEDICINE

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE)

(2008) Constantin Dallas et al.   PHYTOMEDICINE