Overexpression of Sirtuin 6 Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis

Sirtuin 6 protects cardiomyocytes from hypertrophyin vitrovia inhibition of NF-κB-dependent transcriptional activity

(2012) Shan-Shan Yu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

(2012) Rachel Grimley et al.   PLoS One

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

(2011) F. Niederer et al.   ANNALS OF THE RHEUMATIC DISEASES

SPA0355, a thiourea analogue, inhibits inflammatory responses and joint destruction in fibroblast-like synoviocytes and mice with collagen-induced arthritis

(2011) YR Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6

(2011) Eriko Michishita et al.   CELL CYCLE

The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

(2011) Bo Yang et al.   CELL CYCLE

Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells

(2011) Mehdi Shakibaei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor-  Activity in Dendritic Cells

(2011) A. Legutko et al.   JOURNAL OF IMMUNOLOGY

A20 suppresses inflammatory responses and bone destruction in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis

(2010) Young-Sool Hah et al.   ARTHRITIS AND RHEUMATISM

Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis

(2010) Benoit Le Goff et al.   JOINT BONE SPINE

SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310

(2010) K. M. Rothgiesser et al.   JOURNAL OF CELL SCIENCE

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

(2010) T. T. Schug et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

The nuclear signaling of NF-κB: current knowledge, new insights and future perspectives

(2009) Fengyi Wan et al.   CELL RESEARCH

Involvement of sirtuin 1 in airway inflammation and hyperresponsiveness of allergic airway disease

(2009) So Ri Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

(2009) Peter C. Taylor et al.   Nature Reviews Rheumatology

Inhibition of IL-1β-mediated inflammatory responses by the IκBα super-repressor in human fibroblast-like synoviocytes

(2008) Young-Rae Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of SIRT1 Protects Pancreatic  -Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor- B Signaling Pathway

(2008) J.-H. Lee et al.   DIABETES

Regulation of SIRT6 protein levels by nutrient availability

(2008) Yariv Kanfi et al.   FEBS LETTERS

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

(2008) Keith D Brown et al.   ARTHRITIS RESEARCH & THERAPY