Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

(2011) Marco Tafani et al.   Journal of Neuroinflammation

Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

(2010) Marco Tafani et al.   CANCER SCIENCE

Hmgb1 Promotes Wound Healing of 3T3 Mouse Fibroblasts via Rage-Dependent ERK1/2 Activation

(2010) Elia Ranzato et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons

(2010) Felipe Ortega et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent

(2009) Xiujun Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice

(2009) Wen Fu et al.   BMC CANCER

The receptor RAGE: Bridging inflammation and cancer

(2009) Astrid Riehl et al.   Cell Communication and Signaling

Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction

(2009) Katsuhisa Ohashi et al.   CLINICAL IMMUNOLOGY

Regulation of glucose metabolism-related genes and VEGF by HIF-1α and HIF-1β, but not HIF-2α, in gastric cancer

(2009) In-Sung Song et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

P2X7-mediated chemoprevention of epithelial cancers

(2009) George I Gorodeski   EXPERT OPINION ON THERAPEUTIC TARGETS

The NF-κB activation pathways, emerging molecular targets for cancer prevention and therapy

(2009) Yong Lin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A potential role for reactive oxygen species and the HIF-1α–VEGF pathway in hypoxia-induced pulmonary vascular leak

(2009) David C. Irwin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Expression of the P2X7Receptor Increases the Ca2+Content of the Endoplasmic Reticulum, Activates NFATc1, and Protects from Apoptosis

(2009) Elena Adinolfi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAGE: therapeutic target and biomarker of the inflammatory response-the evidence mounts

(2009) Ravichandran Ramasamy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The sour side of neurodegenerative disorders: the effects of protein glycation

(2009) Hugo Vicente Miranda et al.   JOURNAL OF PATHOLOGY

RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation

(2009) Louis J Sparvero et al.   Journal of Translational Medicine

Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma

(2009) Linda Ravenna et al.   PROSTATE

P2X7: a growth-promoting receptor—implications for cancer

(2009) Francesco Di Virgilio et al.   Purinergic Signalling

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Receptor for advanced glycation end-products (RAGE) modulates neutrophil adhesion and migration on glycoxidated extracellular matrix

(2008) Fatouma Touré et al.   BIOCHEMICAL JOURNAL

AGE-RAGE System and Carcinogenesis

(2008) Riichiro Abe et al.   CURRENT PHARMACEUTICAL DESIGN

IκB kinase β (IKKβ/IKK2/IKBKB)—A key molecule in signaling to the transcription factor NF-κB

(2008) Johannes A. Schmid et al.   CYTOKINE & GROWTH FACTOR REVIEWS

RAGE signaling sustains inflammation and promotes tumor development

(2008) Christoffer Gebhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Statins and ATP regulate nuclear pAkt via the P2X7 purinergic receptor in epithelial cells

(2007) Oras Mistafa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression and function of the P2X7 receptor in rat C6 glioma cells

(2007) Wei Wei et al.   CANCER LETTERS

Increased P2X7Receptor Expression and Function in Thyroid Papillary Cancer: A New Potential Marker of the Disease?

(2007) Anna Solini et al.   ENDOCRINOLOGY