标题
TRPM channels in health and disease
作者
关键词
-
出版物
Nature Reviews Nephrology
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2023-10-18
DOI
10.1038/s41581-023-00777-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gain-of-function variants in the ion channel gene TRPM3 underlie a spectrum of neurodevelopmental disorders
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- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
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- TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival
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- Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
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- Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel
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- Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity
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- Chanzyme TRPM7 Mediates the Ca 2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation
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- Mutations in the voltage-sensing domain affect the alternative ion permeation pathway in the TRPM3 channel
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- Structure of full-length human TRPM4
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- Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
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- 8-Br-cADPR, a TRPM2 ion channel antagonist, inhibits renal ischemia-reperfusion injury
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- Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
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- Structure of the mammalian TRPM7, a magnesium channel required during embryonic development
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- Structures and gating mechanism of human TRPM2
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- Polycystic kidney disease
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- The TRPM7 channel kinase regulates store-operated calcium entry
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- Structures of the calcium-activated, non-selective cation channel TRPM4
- (2017) Jiangtao Guo et al. NATURE
- Electron cryo-microscopy structure of a human TRPM4 channel
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- Histone phosphorylation by TRPM6’s cleaved kinase attenuates adjacent arginine methylation to regulate gene expression
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- TRPM7 senses oxidative stress to release Zn2+from unique intracellular vesicles
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- Structure of the cold- and menthol-sensing ion channel TRPM8
- (2017) Ying Yin et al. SCIENCE
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut
- (2017) Andrea Romagnani et al. Nature Communications
- Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels
- (2017) Sandeep Dembla et al. eLife
- TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP
- (2017) Silvia Ferioli et al. Scientific Reports
- The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis
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- Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation
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- Transient Receptor Potential Melastatin 7 Cation Channel KinaseNovelty and Significance
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- TRPM7 kinase activity regulates murine mast cell degranulation
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- The TRPM2 ion channel is required for sensitivity to warmth
- (2016) Chun-Hsiang Tan et al. NATURE
- The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
- (2016) K. Song et al. SCIENCE
- Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg2+ homeostasis and cytoskeletal architecture
- (2016) Simon Stritt et al. Nature Communications
- Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival
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- The TRPM1 channel in ON-bipolar cells is gated by both the α and the βγ subunits of the G-protein Go
- (2016) Ying Xu et al. Scientific Reports
- Properties and functions of TRPM1 channels in the dendritic tips of retinal ON-bipolar cells
- (2015) Franziska M. Schneider et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Essential Role of Transient Receptor Potential M8 (TRPM8) in a Model of Acute Cold-induced Urinary Urgency
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- Cholinergic urethral brush cells are widespread throughout placental mammals
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- Regulation of the transient receptor potential channel TRPM3 by phosphoinositides
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- N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation
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- The TRPM7 Chanzyme Is Cleaved to Release a Chromatin-Modifying Kinase
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- TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions
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- The TRPM6 Kinase Domain Determines the Mg·ATP Sensitivity of TRPM7/M6 Heteromeric Ion Channels
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- Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes
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- The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury
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- Timing of Myocardial Trpm7 Deletion During Cardiogenesis Variably Disrupts Adult Ventricular Function, Conduction, and Repolarization
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- Modulation of NMDAR Subunit Expression by TRPM2 Channels Regulates Neuronal Vulnerability to Ischemic Cell Death
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- TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
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- Molecular Genetics and Functional Anomalies in a Series of 248 Brugada Cases with 11 Mutations in the TRPM4 Channel
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- Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity
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- Cleavage of TRPM7 Releases the Kinase Domain from the Ion Channel and Regulates Its Participation in Fas-Induced Apoptosis
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- TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice
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- TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis
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- TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat
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- The channel kinase, TRPM7, is required for early embryonic development
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- Phosphatidylinositol 4,5-bisphosphate (PIP2) controls magnesium gatekeeper TRPM6 activity
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- Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice
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- Methionine Sulfoxide Reductase B1 (MsrB1) Recovers TRPM6 Channel Activity during Oxidative Stress
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- Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice
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- Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea
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- Polycystins and renovascular mechanosensory transduction
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- TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
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- TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells
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- Mutations in TRPM1 Are a Common Cause of Complete Congenital Stationary Night Blindness
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- TRPM1 Is Mutated in Patients with Autosomal-Recessive Complete Congenital Stationary Night Blindness
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- Recessive Mutations of the Gene TRPM1 Abrogate ON Bipolar Cell Function and Cause Complete Congenital Stationary Night Blindness in Humans
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- Mice defective in Trpm6 show embryonic mortality and neural tube defects
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- Regulation of the Epithelial Mg2+Channel TRPM6 by Estrogen and the Associated Repressor Protein of Estrogen Receptor Activity (REA)
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- Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I
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- A Transient Receptor Potential-Like Channel Mediates Synaptic Transmission in Rod Bipolar Cells
- (2009) Y. Shen et al. JOURNAL OF NEUROSCIENCE
- De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury
- (2009) Volodymyr Gerzanich et al. NATURE MEDICINE
- The role of transient receptor potential channels in kidney disease
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- TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells
- (2009) Catherine W. Morgans et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes
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- RACK1 Inhibits TRPM6 Activity via Phosphorylation of the Fused α-Kinase Domain
- (2008) Gang Cao et al. CURRENT BIOLOGY
- TRPM7 Regulates Myosin IIA Filament Stability and Protein Localization by Heavy Chain Phosphorylation
- (2008) Kristopher Clark et al. JOURNAL OF MOLECULAR BIOLOGY
- Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells
- (2008) Thomas F.J. Wagner et al. NATURE CELL BIOLOGY
- The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells
- (2008) Gaëtan Barbet et al. NATURE IMMUNOLOGY
- TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
- (2008) Shinichiro Yamamoto et al. NATURE MEDICINE
- Massive Autophosphorylation of the Ser/Thr-Rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7
- (2008) Kristopher Clark et al. PLoS One
- Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg2+ Homeostasis
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