标题
Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 28, Issue 7, Pages 604-613
出版商
Springer Science and Business Media LLC
发表日期
2021-06-25
DOI
10.1038/s41594-021-00607-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Extracellular cap domain is an essential component of the TRPV1 gating mechanism
- (2021) Kirill D. Nadezhdin et al. Nature Communications
- Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
- (2020) Katherine E Huffer et al. eLife
- A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel
- (2020) Chang Liu et al. NEURON
- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
- (2019) Ying Yin et al. SCIENCE
- TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2
- (2019) Soichiro Yamaguchi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural insights into TRPM8 inhibition and desensitization
- (2019) Melinda M. Diver et al. SCIENCE
- Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
- (2019) Yihe Huang et al. eLife
- Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
- (2019) Tristan Bepler et al. NATURE METHODS
- Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
- (2018) Taylor E. T. Hughes et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of full-length human TRPM4
- (2018) Jingjing Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
- (2018) Taylor E. T. Hughes et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
- (2018) Zhe Zhang et al. eLife
- Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
- (2018) Yihe Huang et al. NATURE
- New tools for the analysis and validation of cryo-EM maps and atomic models
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Structures and gating mechanism of human TRPM2
- (2018) Longfei Wang et al. SCIENCE
- A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
- (2018) Jasenko Zivanov et al. IUCrJ
- Structures of the calcium-activated, non-selective cation channel TRPM4
- (2017) Jiangtao Guo et al. NATURE
- Electron cryo-microscopy structure of a human TRPM4 channel
- (2017) Paige A. Winkler et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
- (2017) Koenraad Philippaert et al. Nature Communications
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
- (2016) Yuan Gao et al. NATURE
- Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut
- (2016) M. R. Howitt et al. SCIENCE
- GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
- (2015) Makoto Shigeto et al. JOURNAL OF CLINICAL INVESTIGATION
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- L596–W733 bond between the start of the S4–S5 linker and the TRP box stabilizes the closed state of TRPV4 channel
- (2015) Jinfeng Teng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sampling the conformational space of the catalytic subunit of human γ-secretase
- (2015) Xiao-chen Bai et al. eLife
- Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation
- (2014) Lucia Gregorio-Teruel et al. JOURNAL OF GENERAL PHYSIOLOGY
- Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
- (2014) April Goehring et al. Nature Protocols
- CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes
- (2013) Akiyuki Taruno et al. NATURE
- Structural basis for Ca2+ selectivity of a voltage-gated calcium channel
- (2013) Lin Tang et al. NATURE
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- A Study of the Hydration of the Alkali Metal Ions in Aqueous Solution
- (2011) Johan Mähler et al. INORGANIC CHEMISTRY
- The transient receptor potential family of ion channels
- (2011) Bernd Nilius et al. GENOME BIOLOGY
- TRPM5 regulates glucose-stimulated insulin secretion
- (2010) Lili R. Brixel et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice
- (2010) B. Colsoul et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I
- (2008) Pierluigi Valente et al. FASEB JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now