Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
出版年份 2019 全文链接
标题
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
作者
关键词
-
出版物
SCIENCE
Volume 363, Issue 6430, Pages eaav9334
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2019-02-08
DOI
10.1126/science.aav9334
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TRPM channels come into focus
- (2018) Chanhyung Bae et al. SCIENCE
- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Discovery of TRPM8 Antagonist (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine
- (2018) Daniel B. Horne et al. JOURNAL OF MEDICINAL CHEMISTRY
- Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
- (2018) Yihe Huang et al. NATURE
- Conformational ensemble of the human TRPV3 ion channel
- (2018) Lejla Zubcevic et al. Nature Communications
- Structural insights on TRPV5 gating by endogenous modulators
- (2018) Taylor E. T. Hughes et al. Nature Communications
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
- (2018) Jasenko Zivanov et al. IUCrJ
- Structures of the calcium-activated, non-selective cation channel TRPM4
- (2017) Jiangtao Guo et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Structure of the cold- and menthol-sensing ion channel TRPM8
- (2017) Ying Yin et al. SCIENCE
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
- (2016) Yuan Gao et al. NATURE
- Phosphoinositides regulate ion channels
- (2015) Bertil Hille et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain
- (2015) Mark D. Andrews et al. ACS Medicinal Chemistry Letters
- Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
- (2014) April Goehring et al. Nature Protocols
- A Sensory-Labeled Line for Cold: TRPM8-Expressing Sensory Neurons Define the Cellular Basis for Cold, Cold Pain, and Cooling-Mediated Analgesia
- (2013) W. M. Knowlton et al. JOURNAL OF NEUROSCIENCE
- TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
- (2013) Boyi Liu et al. PAIN
- TRPM channels: same ballpark, different players, and different rules in immunogenetics
- (2011) Ammad Ahmad Farooqi et al. IMMUNOGENETICS
- Ligand stoichiometry of the cold- and menthol-activated channel TRPM8
- (2011) Annelies Janssens et al. JOURNAL OF PHYSIOLOGY-LONDON
- Genome-wide association study reveals three susceptibility loci for common migraine in the general population
- (2011) Daniel I Chasman et al. NATURE GENETICS
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Gating of Transient Receptor Potential Melastatin 8 (TRPM8) Channels Activated by Cold and Chemical Agonists in Planar Lipid Bilayers
- (2010) E. Zakharian et al. JOURNAL OF NEUROSCIENCE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Differential Role of the Menthol-Binding Residue Y745 in the Antagonism of Thermally Gated TRPM8 Channels
- (2009) Annika Malkia et al. Molecular Pain
- Inhibition of TRPM8 by Icilin Distinct from Desensitization Induced by Menthol and Menthol Derivatives
- (2008) Frank J. P. Kühn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started