The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

Thermoregulatory disorders and illness related to heat and cold stress

(2016) William P. Cheshire   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Central neural control of thermoregulation and brown adipose tissue

(2016) Shaun F. Morrison   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Therapeutic hypothermia and targeted temperature management in traumatic brain injury: Clinical challenges for successful translation

(2016) W. Dalton Dietrich et al.   BRAIN RESEARCH

The molecular and cellular basis of thermosensation in mammals

(2015) Radhika Palkar et al.   CURRENT OPINION IN NEUROBIOLOGY

Hypothalamic POMC neurons promote cannabinoid-induced feeding

(2015) Marco Koch et al.   NATURE

Hypothermia for acute ischaemic stroke

(2013) Tzu-Ching Wu et al.   LANCET NEUROLOGY

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Diagnosis and treatment of drug-induced hyperthermia

(2012) M. E. Musselman et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation

(2012) Heather Knowles et al.   IMMUNOLOGIC RESEARCH

Neural circuitry engaged by prostaglandins during the sickness syndrome

(2012) Clifford B Saper et al.   NATURE NEUROSCIENCE

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

(2012) M. Kashio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The thermo-TRP ion channel family: properties and therapeutic implications

(2011) Laura Vay et al.   BRITISH JOURNAL OF PHARMACOLOGY

Temperature-dependent STIM1 activation induces Ca2+ influx and modulates gene expression

(2011) Bailong Xiao et al.   Nature Chemical Biology

The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

(2011) Anke Di et al.   NATURE IMMUNOLOGY

TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat

(2011) Joris Vriens et al.   NEURON

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Effects of ZD7288 on firing pattern of thermosensitive neurons isolated from hypothalamus

(2011) Chunqing Cai et al.   NEUROSCIENCE LETTERS

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system

(2011) K. Zimmermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fever

(2011) Tamas Bartfai et al.   TheScientificWorldJOURNAL

A transgenic mouse line for molecular genetic analysis of excitatory glutamatergic neurons

(2010) Lotta Borgius et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response

(2010) James Eberwine et al.   PHARMACOLOGY & THERAPEUTICS

Neurons in the paraventricular nucleus of the hypothalamus inhibit sympathetic outflow to brown adipose tissue

(2009) C. J. Madden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Multiple thermoregulatory effectors with independent central controls

(2009) Robin M. McAllen et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Interleukin (IL)-6 and IL-1β act synergistically within the brain to induce sickness behavior and fever in rats

(2008) Lois M. Harden et al.   BRAIN BEHAVIOR AND IMMUNITY

Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB)

(2008) K Togashi et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

(2008) Shinichiro Yamamoto et al.   NATURE MEDICINE

Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect

(2005) Shang-Zhong Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY