Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes
出版年份 2016 全文链接
标题
Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes
作者
关键词
-
出版物
Marine Drugs
Volume 14, Issue 4, Pages 80
出版商
MDPI AG
发表日期
2016-04-18
DOI
10.3390/md14040080
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Engineering Biosynthesis of Non-ribosomal Peptides and Polyketides by Directed Evolution
- (2016) Zhe Rui et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Isolation and Biosynthetic Analysis of Haliamide, a New PKS-NRPS Hybrid Metabolite from the Marine Myxobacterium Haliangium ochraceum
- (2016) Yuwei Sun et al. MOLECULES
- Unique marine derived cyanobacterial biosynthetic genes for chemical diversity
- (2016) Karin Kleigrewe et al. NATURAL PRODUCT REPORTS
- Recent advances in engineering nonribosomal peptide assembly lines
- (2016) M. Winn et al. NATURAL PRODUCT REPORTS
- Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology
- (2016) Kira J. Weissman NATURAL PRODUCT REPORTS
- Biosynthesis of polyketides by trans-AT polyketide synthases
- (2016) Eric J. N. Helfrich et al. NATURAL PRODUCT REPORTS
- In Vitro Cultivation of ‘Unculturable’ Oral Bacteria, Facilitated by Community Culture and Media Supplementation with Siderophores
- (2016) Sonia R. Vartoukian et al. PLoS One
- Phosphate Limitation Induces Drastic Physiological Changes, Virulence-Related Gene Expression, and Secondary Metabolite Production in Pseudovibrio sp. Strain FO-BEG1
- (2015) Stefano Romano et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria
- (2015) Henrique Machado et al. BMC GENOMICS
- From cultured to uncultured genome sequences: metagenomics and modeling microbial ecosystems
- (2015) Daniel R. Garza et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Molecular Networking and Pattern-Based Genome Mining Improves Discovery of Biosynthetic Gene Clusters and their Products from Salinispora Species
- (2015) Katherine R. Duncan et al. CHEMISTRY & BIOLOGY
- Genomic insights into the distribution, genetic diversity and evolution of polyketide synthases and nonribosomal peptide synthetases
- (2015) Hao Wang et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743
- (2015) Michael M. Schofield et al. ENVIRONMENTAL MICROBIOLOGY
- New Drugs from Marine Organisms in Alzheimer’s Disease
- (2015) Patrizia Russo et al. Marine Drugs
- Emerging Concepts Promising New Horizons for Marine Biodiscovery and Synthetic Biology
- (2015) F. Reen et al. Marine Drugs
- The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine Microorganisms
- (2015) F. Reen et al. Marine Drugs
- A new antibiotic kills pathogens without detectable resistance
- (2015) Losee L. Ling et al. NATURE
- Twenty years of bacterial genome sequencing
- (2015) Nicholas J. Loman et al. NATURE REVIEWS MICROBIOLOGY
- Discovery of microbial natural products by activation of silent biosynthetic gene clusters
- (2015) Peter J. Rutledge et al. NATURE REVIEWS MICROBIOLOGY
- Norine, the knowledgebase dedicated to non-ribosomal peptides, is now open to crowdsourcing
- (2015) Areski Flissi et al. NUCLEIC ACIDS RESEARCH
- antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
- (2015) Tilmann Weber et al. NUCLEIC ACIDS RESEARCH
- The Pfam protein families database: towards a more sustainable future
- (2015) Robert D. Finn et al. NUCLEIC ACIDS RESEARCH
- Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology
- (2015) Christian Hertweck TRENDS IN BIOCHEMICAL SCIENCES
- Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates
- (2015) Marla Trindade et al. Frontiers in Microbiology
- The Road to Metagenomics: From Microbiology to DNA Sequencing Technologies and Bioinformatics
- (2015) Alejandra Escobar-Zepeda et al. Frontiers in Genetics
- Detection of polyketide synthase and nonribosomal peptide synthetase biosynthetic genes from antimicrobial coral-associated actinomycetes
- (2014) Jie Li et al. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY
- Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases
- (2014) M. Till et al. BIOTECHNOLOGY LETTERS
- Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products
- (2014) Mark J. Calcott et al. BIOTECHNOLOGY LETTERS
- Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria
- (2014) Alexandra Calteau et al. BMC GENOMICS
- Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
- (2014) Peter Cimermancic et al. CELL
- Acyl-Homoserine Lactone Quorum Sensing in the Roseobacter Clade
- (2014) Jindong Zan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Scrutinizing the Scaffolds of Marine Biosynthetics from Different Source Organisms: Gram-Negative Cultured Bacterial Products Enter Center Stage
- (2014) Patrick C. Still et al. JOURNAL OF NATURAL PRODUCTS
- Polyketide Synthases in the Microbiome of the Marine Sponge Plakortis halichondrioides: A Metagenomic Update
- (2014) Gerardo Della Sala et al. Marine Drugs
- Diversity, abundance and natural products of marine sponge-associated actinomycetes
- (2014) Usama Ramadan Abdelmohsen et al. NATURAL PRODUCT REPORTS
- The Genomes OnLine Database (GOLD) v.5: a metadata management system based on a four level (meta)genome project classification
- (2014) T.B.K. Reddy et al. NUCLEIC ACIDS RESEARCH
- Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes
- (2014) H. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora
- (2014) N. Ziemert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges
- (2013) Jason N Woodhouse et al. ISME Journal
- Identification of micromonolactam, a new polyene macrocyclic lactam from two marine Micromonospora strains using chemical and molecular methods: clarification of the biosynthetic pathway from a glutamate starter unit
- (2013) Elizabeth Julia Skellam et al. JOURNAL OF ANTIBIOTICS
- Antagonistic Interactions Mediated by Marine Bacteria: The Role of Small Molecules
- (2013) Matthias Wietz et al. JOURNAL OF CHEMICAL ECOLOGY
- Challenges and triumphs to genomics-based natural product discovery
- (2013) Paul R. Jensen et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides
- (2013) Christopher N. Boddy JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
- (2013) Brian O. Bachmann et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Genome mining of Streptomyces ambofaciens
- (2013) Bertrand Aigle et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Apratoxin H and Apratoxin A Sulfoxide from the Red Sea Cyanobacterium Moorea producens
- (2013) Christopher C. Thornburg et al. JOURNAL OF NATURAL PRODUCTS
- Molecular Networking as a Dereplication Strategy
- (2013) Jane Y. Yang et al. JOURNAL OF NATURAL PRODUCTS
- Antimicrobial Peptides from Marine Proteobacteria
- (2013) Florie Desriac et al. Marine Drugs
- IMG/M 4 version of the integrated metagenome comparative analysis system
- (2013) Victor M. Markowitz et al. NUCLEIC ACIDS RESEARCH
- IMG 4 version of the integrated microbial genomes comparative analysis system
- (2013) Victor M. Markowitz et al. NUCLEIC ACIDS RESEARCH
- Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models
- (2013) Barzan I. Khayatt et al. PLoS One
- Polyketide genes in the marine spongePlakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts
- (2013) Gerardo Della Sala et al. Environmental Microbiology Reports
- Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics
- (2012) Katerina Nikolouli et al. BIOTECHNOLOGY LETTERS
- Diverse Secondary Metabolites Produced by Marine-Derived Fungus Nigrospora sp. MA75 on Various Culture Media
- (2012) Zhuo Shang et al. CHEMISTRY & BIODIVERSITY
- Combinatorial biosynthesis of polyketides—a perspective
- (2012) Fong T Wong et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Growing Unculturable Bacteria
- (2012) E. J. Stewart JOURNAL OF BACTERIOLOGY
- Genomic Mining for Novel FADH2-Dependent Halogenases in Marine Sponge-Associated Microbial Consortia
- (2012) Kristina Bayer et al. MARINE BIOTECHNOLOGY
- Diversity of Nonribosomal Peptide Synthetase Genes in the Microbial Metagenomes of Marine Sponges
- (2012) Sheila Marie Pimentel-Elardo et al. Marine Drugs
- Transforming clinical microbiology with bacterial genome sequencing
- (2012) Xavier Didelot et al. NATURE REVIEWS GENETICS
- Genomic insights into the marine sponge microbiome
- (2012) Ute Hentschel et al. NATURE REVIEWS MICROBIOLOGY
- ClusterMine360: a database of microbial PKS/NRPS biosynthesis
- (2012) Kyle R. Conway et al. NUCLEIC ACIDS RESEARCH
- The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity
- (2012) Nadine Ziemert et al. PLoS One
- Meta-omic Characterization of the Marine Invertebrate Microbial Consortium That Produces the Chemotherapeutic Natural Product ET-743
- (2011) Christopher M. Rath et al. ACS Chemical Biology
- Landscape of Next-Generation Sequencing Technologies
- (2011) Thomas P. Niedringhaus et al. ANALYTICAL CHEMISTRY
- The great screen anomaly—a new frontier in product discovery through functional metagenomics
- (2011) David Matthias Ekkers et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Assessing the complex sponge microbiota: core, variable and species-specific bacterial communities in marine sponges
- (2011) Susanne Schmitt et al. ISME Journal
- Production of Bioactive Secondary Metabolites by Marine Vibrionaceae
- (2011) Maria Mansson et al. Marine Drugs
- The sequence read archive: explosive growth of sequencing data
- (2011) Y. Kodama et al. NUCLEIC ACIDS RESEARCH
- NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity
- (2011) Marc Röttig et al. NUCLEIC ACIDS RESEARCH
- Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage
- (2011) Rashel V. Grindberg et al. PLoS One
- tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics
- (2011) W. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and genetics of circular bacteriocins
- (2011) Marco J. van Belkum et al. TRENDS IN MICROBIOLOGY
- Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity
- (2011) Qi-Yin Chen et al. ACS Medicinal Chemistry Letters
- Expanding Small-Molecule Functional Metagenomics through Parallel Screening of Broad-Host-Range Cosmid Environmental DNA Libraries in Diverse Proteobacteria
- (2010) J. W. Craig et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Use of Ichip for High-Throughput In Situ Cultivation of "Uncultivable" Microbial Species
- (2010) D. Nichols et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Recent progress and new challenges in metagenomics for biotechnology
- (2010) Ludmila Chistoserdova BIOTECHNOLOGY LETTERS
- The Discovery of Salinosporamide K from the Marine Bacterium “Salinispora pacifica” by Genome Mining Gives Insight into Pathway Evolution
- (2010) Alessandra S. Eustáquio et al. CHEMBIOCHEM
- Horizontal Transfer of a Large and Highly Toxic Secondary Metabolic Gene Cluster between Fungi
- (2010) Jason C. Slot et al. CURRENT BIOLOGY
- Nonribosomal peptide synthetases: structures and dynamics
- (2010) Matthias Strieker et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Uncultured microorganisms as a source of secondary metabolites
- (2010) Kim Lewis et al. JOURNAL OF ANTIBIOTICS
- Marine Myxobacteria as a Source of Antibiotics—Comparison of Physiology, Polyketide-Type Genes and Antibiotic Production of Three New Isolates of Enhygromyxa salina
- (2010) Till F. Schäberle et al. Marine Drugs
- Marine Metagenomics: New Tools for the Study and Exploitation of Marine Microbial Metabolism
- (2010) Jonathan Kennedy et al. Marine Drugs
- SBSPKS: structure based sequence analysis of polyketide synthases
- (2010) Swadha Anand et al. NUCLEIC ACIDS RESEARCH
- Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource
- (2010) S. Sun et al. NUCLEIC ACIDS RESEARCH
- Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
- (2010) M. Mocibob et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hollow-Fiber Membrane Chamber as a Device for In Situ Environmental Cultivation
- (2009) Y. Aoi et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Achievements and new knowledge unraveled by metagenomic approaches
- (2009) Carola Simon et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Automated genome mining for natural products
- (2009) Michael HT Li et al. BMC BIOINFORMATICS
- Strategies for the Discovery of New Natural Products by Genome Mining
- (2009) Malek Zerikly et al. CHEMBIOCHEM
- Evolution of metabolic diversity: Insights from microbial polyketide synthases
- (2009) Holger Jenke-Kodama et al. PHYTOCHEMISTRY
- The metagenomics RAST server – a public resource for the automatic phylogenetic and functional analysis of metagenomes
- (2008) F Meyer et al. BMC BIOINFORMATICS
- Evolution and taxonomic distribution of nonribosomal peptide and polyketide synthases
- (2008) Grigoris D Amoutzias et al. Future Microbiology
- Genome Mining for Novel Natural Product Discovery
- (2008) Gregory L. Challis JOURNAL OF MEDICINAL CHEMISTRY
- The evolution of gene collectives: How natural selection drives chemical innovation
- (2008) M. A. Fischbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase
- (2008) A. Tanovic et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started