Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743

The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation

(2014) Mulchand S. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uniting the classification of cultured and uncultured bacteria and archaea using 16S rRNA gene sequences

(2014) Pablo Yarza et al.   NATURE REVIEWS MICROBIOLOGY

Host Control of Symbiont Natural Product Chemistry in Cryptic Populations of the Tunicate Lissoclinum patella

(2014) Jason C. Kwan et al.   PLoS One

Core Assembly Mechanism of Quinocarcin/SF-1739: Bimodular Complex Nonribosomal Peptide Synthetases for Sequential Mannich-type Reactions

(2013) Tomoshige Hiratsuka et al.   CHEMISTRY & BIOLOGY

Defensive Bacteriome Symbiont with a Drastically Reduced Genome

(2013) Atsushi Nakabachi et al.   CURRENT BIOLOGY

IMG/M 4 version of the integrated metagenome comparative analysis system

(2013) Victor M. Markowitz et al.   NUCLEIC ACIDS RESEARCH

IMG 4 version of the integrated microbial genomes comparative analysis system

(2013) Victor M. Markowitz et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides

(2013) Auke J. van Heel et al.   NUCLEIC ACIDS RESEARCH

Bacterial Endosymbiosis in a Chordate Host: Long-Term Co-Evolution and Conservation of Secondary Metabolism

(2013) Jason C. Kwan et al.   PLoS One

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly line

(2012) C. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome streamlining and chemical defense in a coral reef symbiosis

(2012) J. C. Kwan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meta-omic Characterization of the Marine Invertebrate Microbial Consortium That Produces the Chemotherapeutic Natural Product ET-743

(2011) Christopher M. Rath et al.   ACS Chemical Biology

Evolution of an endofungal Lifestyle: Deductions from the Burkholderia rhizoxinica Genome

(2011) Gerald Lackner et al.   BMC GENOMICS

From hormones to secondary metabolism: the emergence of metabolic gene clusters in plants

(2011) Hoi Yee Chu et al.   PLANT JOURNAL

Automated genome mining for natural products

(2009) Michael HT Li et al.   BMC BIOINFORMATICS

Deletional Bias across the Three Domains of Life

(2009) Chih-Horng Kuo et al.   Genome Biology and Evolution

The consequences of genetic drift for bacterial genome complexity

(2009) C.-H. Kuo et al.   GENOME RESEARCH

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

(2009) T. Weber et al.   JOURNAL OF BIOTECHNOLOGY

Endosymbiotic Bacteria in Insects: Their Diversity and Culturability

(2009) Yoshitomo Kikuchi   MICROBES AND ENVIRONMENTS

Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem

(2009) Carmen Cuevas et al.   NATURAL PRODUCT REPORTS

Host cell-free growth of the Q fever bacterium Coxiella burnetii

(2009) A. Omsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Community-wide analysis of microbial genome sequence signatures

(2009) Gregory J Dick et al.   GENOME BIOLOGY

Genomics and Evolution of Heritable Bacterial Symbionts

(2008) Nancy A. Moran et al.   Annual Review of Genetics

Metabolites from symbiotic bacteria

(2008) Jörn Piel   NATURAL PRODUCT REPORTS